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Materias / palabras clave: Genome; Genotyping; Computational biology; Reference genome; Haplotype; Search engine indexing; Population; Biology; Computer science; Genomics; Genetics; Human genome

Materias / palabras clave: Population stratification; Spurious relationship; Biology; Principal component analysis; Allele frequency; Genetic association; Genome-wide association study; Population; Evolutionary biology; Computational biology; Geno...

BACKGROUND: The evolutionary analysis of molecular sequence variation is a statistical enterprise. This is reflected in the increased use of probabilistic models for phylogenetic inference, multiple sequence alignment, a...

The identification of genetically homogeneous groups of individuals is a long standing issue in population genetics. A recent Bayesian algorithm implemented in the software STRUCTURE allows the identification of such gro...

The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report comp...

Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although di...

Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. Here we describe the aggregation and analysis of high-quality exome (protein-...

UNLABELLED: Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particularly in the context of medical genetic association studies, i...

The relationship between the two estimates of genetic variation at the DNA level, namely the number of segregating sites and the average number of nucleotide differences estimated from pairwise comparison, is investigate...

Abstract Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that are crucial for the function of an organism will be dep...

Part 1 Introduction - preliminary demarcation of a type of Bourgeois Public Sphere: the initial question remarks on the type representative publicness on the genesis of the Bourgois Public Sphere. Part 2 Social structure...

MOTIVATION: Chimeric DNA sequences often form during polymerase chain reaction amplification, especially when sequencing single regions (e.g. 16S rRNA or fungal Internal Transcribed Spacer) to assess diversity or compare...

BACKGROUND: VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data. It is designed as an alternative to...

Genetic algorithms have been used in science and engineering as adaptive algorithms for solving practical problems and as computational models of natural evolutionary systems. This brief, accessible introduction describe...

Biogeography was stuck in a "natural history phase" dominated by the collection of data, the young Princeton biologists Robert H. MacArthur and Edward O. Wilson argued in 1967. In this book, the authors developed a gener...

Materias / palabras clave: gene, rna, genetic diseases, livestock and population genetics, epigenomics; Science: Biology (General): Genetics

Materias / palabras clave: gene discovery, population genetics, genome projects, comparative genomics, functional genomics, medical genetics; Science: Biology (General): Genetics

Materias / palabras clave: population genetics, functional genetics, genetic disease, pharmacogenetics; Medicine: Medicine (General); Science: Biology (General): Genetics

Materias / palabras clave: zoology, evolutionary biology, population genetics, systematic zoology; Science: Zoology; Science: Biology (General): Evolution

Materias / palabras clave: human biology, population biology, human genetics, human development, human body, human physiology; Science: Biology (General); Science: Human anatomy; Science: Physiology

Materias / palabras clave: genome and sequence analysis, gene and protein expression, genetics and population analysis, comparative genomics, computational functional genomics, protein dynamics and function; Medicine: Internal medicine: Neuroscien...

Materias / palabras clave: bioinformatics, computational biology, genomics, gene expression, genetic and population analysis, data and text mining; Science: Biology (General): Genetics