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To test the hypothesis that lecturing maximizes learning and course performance, we metaanalyzed 225 studies that reported data on examination scores or failure rates when comparing student performance in undergraduate s...

We demonstrate a composite medium, based on a periodic array of interspaced conducting nonmagnetic split ring resonators and continuous wires, that exhibits a frequency region in the microwave regime with simultaneously ...

Developments in genome-wide association studies and the increasing availability of summary genetic association data have made application of Mendelian randomization relatively straightforward. However, obtaining reliable...

Using the freedom of design that metamaterials provide, we show how electromagnetic fields can be redirected at will and propose a design strategy. The conserved fields-electric displacement field D, magnetic induction f...

Materias / palabras clave: DNA ligase; DNA; Exonuclease; DNA polymerase; DNA clamp; Ligase chain reaction; Biology; In vitro recombination; Computational biology; Gene; Chemistry; Genetics

We present experimental scattering data at microwave frequencies on a structured metamaterial that exhibits a frequency band where the effective index of refraction (n) is negative. The material consists of a two-dimensi...

Materias / palabras clave: Quantum computer; Computer science; Qubit; Human genome; DNA sequencing; Computational biology; Genome; Algorithm; Biology; Genetics; Theoretical computer science; Quantum

Materias / palabras clave: Maxima and minima; Computer science; Robustness (evolution); Image registration; Artificial intelligence; Global optimization; Interpolation (computer graphics); Optimization problem; Computer vision; Motion (physics); A...

BACKGROUND: The number of Mendelian randomization analyses including large numbers of genetic variants is rapidly increasing. This is due to the proliferation of genome-wide association studies, and the desire to obtain ...

BACKGROUND: Subjects with a mild cognitive impairment (MCI) have a memory impairment beyond that expected for age and education yet are not demented. These subjects are becoming the focus of many prediction studies and e...

(Abridged) The 7-year WMAP data and improved astrophysical data rigorously test the standard cosmological model and its extensions. By combining WMAP with the latest distance measurements from BAO and H0 measurement, we ...

Computer vision applications have come to rely increasingly on superpixels in recent years, but it is not always clear what constitutes a good superpixel algorithm. In an effort to understand the benefits and drawbacks o...

BACKGROUND: Blockade of programmed death 1 (PD-1), an inhibitory receptor expressed by T cells, can overcome immune resistance. We assessed the antitumor activity and safety of BMS-936558, an antibody that specifically b...

W. Wilson's (1967) review of the area of subjective well-being (SWB) advanced several conclusions regarding those who report high levels of A number of his conclusions have been overturned: youth and modest aspirations n...

Materias / palabras clave: Computer science; Segmentation; Tracing; Artificial intelligence; Context (archaeology); Reliability (semiconductor); Set (abstract data type); Image segmentation; Machine learning; Physics; Power (physics); Operating sy...

We have developed three computer programs for comparisons of protein and DNA sequences. They can be used to search sequence data bases, evaluate similarity scores, and identify periodic structures based on local sequence...

Abstract Motivation: Many programs for aligning short sequencing reads to a reference genome have been developed in the last 2 years. Most of them are very efficient for short reads but inefficient or not applicable for ...

The 2008 crash has left all the established economic doctrines - equilibrium models, real business cycles, disequilibria models - in disarray. Part of the problem is due to Smith’s veil of ignorance: individuals unknow...