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BACKGROUND: Hyperglycemia and insulin resistance are common in critically ill patients, even if they have not previously had diabetes. Whether the normalization of blood glucose levels with insulin therapy improves the p...

OBJECTIVE: To determine the incidence, cost, and outcome of severe sepsis in the United States. DESIGN: Observational cohort study. SETTING: All nonfederal hospitals (n = 847) in seven U.S. states. PATIENTS: All patients...

BACKGROUND: Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. METHODS...

BACKGROUND: Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen deliver...

Importance: There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19). Objective: To describe the clinical charac...

This paper presents the form and validation results of APACHE II, a severity of disease classification system. APACHE II uses a point score based upon initial values of 12 routine physiologic measurements, age, and previ...

Knaus, William A. MD; Draper, Elizabeth A. RN, MS; Wagner, Douglas P. PhD; Zimmerman, Jack E. MD Author Information

Materias / palabras clave: Medicine; ARDS; Pneumonia; Intensive care unit; Retrospective cohort study; Mechanical ventilation; Incidence (geometry); Intensive care; Severity of illness; APACHE II; Internal medicine; Pediatrics

Importance: In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patien...

To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 international experts representing 30 international...

BACKGROUND: The American Heart Association, in conjunction with the National Institutes of Health, annually reports on the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, inc...

Materias / palabras clave: critical illness, intensive care; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: anaesthesia, intensive care, perioperative medicine, pain medicine, critical emergency care, analgesia; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: intensive and critical care, trauma, pediatric intensive care, acute and emergency medicine, resuscitation, organ dysfunction; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: critical care, clinical research, intensive care, medical education; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: critical care, intensive care, emergency medicine; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: emergency medicine, critical care, intensive care; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: critical care, cardiology, neurology, pediatric, sepsis; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: critical care; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: cardiopulmonary resuscitation, acute cardiovascular diseases, acute respiratory failure, infection, emergency, critical care; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: anesthesia, pain medicine, analgesia, critical care, emergency medicine, perioperative medicine; Medicine: Surgery: Anesthesiology; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First a...

Materias / palabras clave: trauma surgery, acute care surgery, injury prevention, trauma management; Medicine: Surgery; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid

Materias / palabras clave: pre-hospital and hospital emergency medicine, intensive care unit, disaster management, acute major trauma, acute heart disease, acute toxicity; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive ...

Materias / palabras clave: intensive care unit, care bundle, anesthesia, echocardiography, acute respiratory failure, trauma; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid