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Materias / palabras clave: molecular genetics, genomic medicine, human genetics, genomics, medical genetics, personalised medicine; Science: Biology (General): Genetics

Materias / palabras clave: molecular genetics, metabolic pathways, inborn metabolic diseases, inherited metabolic disorders, mendelian conditions, metabolic dysfunction; Medicine: Medicine (General); Science: Biology (General)

Materias / palabras clave: Genetic engineering; Ingeniería genética; Molecular genetics; Genética molecular

Materias / palabras clave: Biología molecular; Bioquímica; Genética; Biochemistry; Molecular biology; Genetics

Materias / palabras clave: Enfermedades respiratorias; Aparatos respiratorios; Genética; Genetics; Molecular genetics; Fibrosis; Medical genetics; Respiratory organs; Diseases; Fibrosis quística

Materias / palabras clave: Genetics, Medical; Molecular genetics; Human chromosome abnormalities; Genética médica; Genética molecular; Anormalidades de los cromosomas humanos

Materias / palabras clave: Genética; Genética molecular; Genetics; Molecular genetics

Materias / palabras clave: Genética; Publicaciones periódicas; Genética humana; Genetics; Periodicals; Human genetics

Materias / palabras clave: Evolutionary biology; Human evolutionary genetics; Genetics; Biology; Molecular genetics; Computational biology; Genome; Gene

With its theoretical basis firmly established in molecular evolutionary and population genetics, the comparative DNA and protein sequence analysis plays a central role in reconstructing the evolutionary histories of spec...

Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species. He...

We present the latest version of the Molecular Evolutionary Genetics Analysis (Mega) software, which contains many sophisticated methods and tools for phylogenomics and phylomedicine. In this major upgrade, Mega has been...

The Molecular Evolutionary Genetics Analysis (Mega) software implements many analytical methods and tools for phylogenomics and phylomedicine. Here, we report a transformation of Mega to enable cross-platform use on Micr...

The Molecular Evolutionary Genetics Analysis (MEGA) software has matured to contain a large collection of methods and tools of computational molecular evolution. Here, we describe new additions that make MEGA a more comp...

We announce the release of the fourth version of MEGA software, which expands on the existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence a...

Materias / palabras clave: Medical genetics; Workgroup; Exome sequencing; Context (archaeology); Exome; Genomics; Genetic testing; Genetics; Whole genome sequencing; Genetic association; Computational biology; Biology

Abstract The Molecular Evolutionary Genetics Analysis (MEGA) software has matured to contain a large collection of methods and tools of computational molecular evolution. Here, we describe new additions that make MEGA a ...

We present here a framework for the study of molecular variation within a single species. Information on DNA haplotype divergence is incorporated into an analysis of variance format, derived from a matrix of squared-dist...

A method is presented for the rapid isolation of high molecular weight plant DNA (50,000 base pairs or more in length) which is free of contaminants which interfere with complete digestion by restriction endonucleases. T...

Computational evolutionary biology, statistical phylogenetics and coalescent-based population genetics are becoming increasingly central to the analysis and understanding of molecular sequence data. We present the Bayesi...

We analysed primary breast cancers by genomic DNA copy number arrays, DNA methylation, exome sequencing, messenger RNA arrays, microRNA sequencing and reverse-phase protein arrays. Our ability to integrate information ac...

Materias / palabras clave: Biology; Suite; Software; Software suite; Scale (ratio); Software development; Sequence (biology); Computational biology; Data science; Bioinformatics; Computer science; Genetics

Materias / palabras clave: Biology; Molecular genetics; Gene; Genetics; Molecular marker; Beta-glucuronidase; Library science; Gene expression; Computer science

Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees, we developed a new mathematical method for estimating the number of transitional and transve...