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Abstract: A considerable number of students have learning difficulties and low academic performance, yet their evaluation does not always lead to a concrete diagnosis. They are categorized as immature, but neither the na...

Abstract Background Early-life environmental exposures may influence infant neurodevelopment. We examined associations between perinatal air pollution, green space exposure, and milestone attainment during the first two ...

Abstract Objectives To evaluate the performance of Intergrowth-21 st (INT) and Fetal Medicine Foundation (FMF) curves in predicting perinatal and neurodevelopmental outcomes in newborns weighing below the 3rd percentile...

Prenatal anxiety and depression in pandemic context could introduce changes in the fetal developmental trajectories that, ultimately, could alter the adaptive behaviors of the offspring, potentially affecting, for exampl...

PurposeThe rehabilitation of neurodevelopmental disabilities is a complex process aimed at enhancing children’s functional abilities, minimizing the impact of disabilities on family dynamics, and promoting autonomy in ...

Abstract: Background: A deficiency of vitamin D during pregnancy has a negative impact on maternal-infant health. Objective: To evaluate the effect of vitamin D status during pregnancy on offspring neurodevelopmental ou...

Subjects / keywords: rare disorders; neurodevelopment; sleep disorder; wearables; sleep architecture

Numerous studies have emphasised the importance of the gut microbiota during early life and its role in modulating neurodevelopment and behaviour. Epidemiological studies have shown that early-life antibiotic exposure ca...

The early stages of life constitute a crucial period for neurodevelopment, during which maternal gut microbiota dysbiosis can impact offspring neurodevelopment via the microbiota–gut–brain axis. This study aimed to e...

There is a large consensus that the prenatal environment determines the susceptibility to pathological conditions later in life. The hypothesis most widely accepted is that exposure to insults inducing adverse conditions...

Abstract Background Young people who fail to develop language as expected face significant challenges in all aspects of life. Unfortunately, language disorders are common, either as a distinct condition (e.g., Developmen...

ABSTRACT Objective This is a protocol for a Campbell review. The aim of this scoping review is to identify and map the available evidence on the association of antenatal cytokine concentrations with neurodevelopmental di...

Maternal diabetes constitutes an unfavorable intrauterine environment for offspring development. Although it is known that diabetes can cause brain alterations and increased risk for neurologic disorders, the relationshi...

Abstract Background Variants in OTUD5 are associated with neurodevelopmental disorders (NDDs), yet the underlying molecular mechanisms remain unclear. This study aimed to investigate the pathogenicity of a novel OTUD5 va...

Abstract Background Since 1990, the survival rate of very preterm (VP) infants (born 

Triclosan (TCS) is widely applied to daily necessities as a chemical bacteriostatic agent. Environmental TCS levels have increased significantly following the coronavirus disease 2019 pandemic, posing a potential threat ...

Metabolic syndrome (MetS) is defined by the concurrence of different metabolic conditions: obesity, hypertension, dyslipidemia, and hyperglycemia. Its incidence has been increasingly rising over the past decades and has ...

Abstract Mutations in the CYFIP2 gene, particularly the R87C variant, are associated with severe epileptic encephalopathy, and present challenges for therapeutic development. This study utilized CRISPR/Cas9-edited human ...

Background/objectivesNeurofibromatosis type 1 (NF1) is a common genetic disorder often accompanied by cognitive, behavioral, and neurodevelopmental disorders. While tumor-related manifestations are well-documented, less ...

Background and purposeWe observed that some late-term fetal prenatal magnetic resonance imaging (MRI) scans revealed normal brain structures but exhibited diffuse hyperintense signals on T2-weighted imaging (T2WI) in the...

ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contribut...

Abstract Introduction Ventriculomegaly (VM) is one the most frequent anomalies detected on prenatal ultrasound. Magnetic resonance imaging (MRI) may enhance diagnostic accuracy and prediction of developmental outcome i...

Background. Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders worldwide and remains an important public health concern. The disorder is characterized by persistent ina...