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Psoriasis is a chronic, inflammatory, autoimmune skin disease affecting 2–4% of general population. It is an important social issue, because of its confirmed associations with metabolic syndrome. Individals with psoria...

Psoriasis is a chronic inflammatory skin disease associated with increased proliferation of the epidermis. Combination of genetic, immunological and environmental factors underlies the skin lesion. Until recently, psoria...

Nowadays it is known that psoriasis belongs to the group of autoimmune diseases and may coexist with other diseases in this group. Most often patients have psoriatic arthritis, rheumatoid arthritis, inflammatory bowel di...

Psoriasis often affects specific locations such as the nail apparatus, scalp, hands, feet, and genital areas. It usually coexists with severe plaque psoriasis. However in some cases only these areas may be affected, caus...

Psoriasis is a chronic inflammatory skin disease which concerns approx. 1-3% population worldwide. In children psoriasis is less common, with the peak of morbidity in teenagers. Because of its more common prevelance in c...

Introduction. Psoriasis rupioides is a rare type of psoriasis. Although a description of it is easy to find in most textbooks of psoriasis, it does not have a place in the ICD-10 classification, and there have been ver...

Introduction. The correlation between psoriasis and metabolic syndrome has been well established. Psoriasis may also coexist with autoimmune blistering disease, mainly bullous pemphigoid. The pathogenetic relationship b...

Psoriasis is a chronic inflammatory disease affecting approximately 1–3% of the general population. Although skin lesions are the primary clinical manifestation of the condition, psoriasis – especially moderate to se...

Psoriasis is one of the most common chronic inflammatory dermatoses. We present the second part of the diagnostic and therapeutic guidelines on psoriasis. The second part discusses the principles of treatment of plaque p...

Subjects / keywords: psoriasis; children; treatment; recommendations

Introduction. Anti-tumor necrosis factor α (anti-TNF-α) antibodies are used to treat immune-mediated inflammatory diseases (IMID), which include inflammatory bowel diseases or psoriasis. In the group of adverse events...

Psoriasis is a chronic disease characterized by a complex immunopathogenesis of recurrent inflammation of the skin. The course and intensity of the disease depend on many genetic, environmental and behavioural factors....

Psoriasis is a chronic inflammatory skin disease with a complex aetiology. One of the methods of treating psoriasis is phototherapy, and the main phototherapeutic modalities include NB-UVB and PUVA. Phototherapy is con...

ABSTRACT Background and Objectives Systemic inflammation indices derived from complete blood counts (CBC) are accessible markers of inflammatory burden, but their relationship with circulating cytokines in psoriasis rema...

Introduction . Psoriasis is a chronic inflammatory skin disease affecting approximately 2–3% of the general population. It is a condition with immunological and genetic background, coexisting with psoriatic arthritis i...

ABSTRACT Disturbance of commensal intestinal microbiota is related to chronic inflammatory dermatosis. We analyzed the diversity of the gut microbiota to characterize the biological variation of psoriasis (Ps). Significa...

Psoriasis is a long-lasting inflammatory skin disease with an autoimmunological and immunometabolic background. The latest European data indicate that the occurrence of psoriasis in children ranges from 0.7% to 2.1%. Des...

Introduction . Omega-3 fatty acids are largely derived from fish oils and are known to decrease inflammation. There have been a few small studies showing the beneficial effect of omega-3 fatty acids in psoriasis. Objec...

ABSTRACT Background and Aim Psoriasis is a skin disorder complicated by arthritis and enthesitis. The cytokines interleukin (IL)‐17, IL‐23, and tumor necrosis factor (TNF)‐α are reportedly key effectors of psorias...

Guselkumab, a monoclonal antibody that targets the interleukin-23 p19 subunit, has demonstrated considerable efficacy in the management of moderate-to-severe plaque psoriasis and psoriatic arthritis through the inhibiti...

Abstract Background Erythrodermic psoriasis (EP) is a severe, systemic inflammatory dermatosis. While kidney involvement is rare, the massive cytokine release associated with EP can induce systemic complications. We repo...

Methotrexate (MTX) is commonly used in dermatology, mainly in patients with psoriasis and psoriatic arthritis. Gastrointestinal disorders, mouth ulcerations, malaise, hair loss, hepatic dysfunction and bone marrow suppre...

Introduction. Generalised pustular psoriasis (GPP) is regarded as a rare clinical subtype of psoriasis. The severity of GPP varies from a benign, chronic course to severe and widespread, life-threatening disease. Due ...

IgA nephropathy is the most common primary glomerulonephritis worldwide. Painless macroscopic hematuria is frequent in children and often coincides with infections of the upper respiratory tract and/ or digestive system....