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Ricerca accademica
Stem cells: basic research on health, from ethics to panacea
Articolo
Articolo
Stem cells: basic research on health, from ethics to panacea
Naara Luna et al · Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) · 2007 · ISSN 1414-3283
Even though stem cell therapies are still under experimentation, the media has represented them as a panacea that would cure all diseases. This fact secured the authorization for using human embryos as research material....
LCC LCC:Public aspects of medicineIdioma Inglés
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Bcl-xL, Bax, and caspase-3 immunoexpression in mesenchymal stem cells of rat bone marrow and adipose tissue subjected to chondrogenic differentiation with and without triiodothyronine: comparative study
Articolo
Articolo
Bcl-xL, Bax, and caspase-3 immunoexpression in mesenchymal stem cells of rat bone marrow and adipose tissue subjected to chondrogenic differentiation with and without triiodothyronine: comparative study
A.C. Poncio et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2025 · ISSN 1678-4162
ABSTRACT This study aims to evaluate and compare the Bcl-xL, Bax, and caspase-3 immunoexpression in rat mesenchymal stem cells (bone marrow [BM-MSC] and adipose tissue [ASC]) with and without in vitro triiodothyronine (T...
LCC LCC:Animal cultureIdioma Inglés
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Biocompatibility, inflammatory response, and antimicrobial properties of single-bottle adhesives on gingival fibroblast and human dental pulp stem cells
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Articolo
Biocompatibility, inflammatory response, and antimicrobial properties of single-bottle adhesives on gingival fibroblast and human dental pulp stem cells
Amir Hafez Ibrahim et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract The purpose of this study was to evaluate how universal adhesives affected the proliferation of gingival fibroblasts and human dental pulp stem cells by measuring cell viability at different time points: 1 min,...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma Inglés
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Bone marrow mononuclear cells versus mesenchymal stem cells from adipose tissue on bone healing in an Old World primate: can this be extrapolated to humans?
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Articolo
Bone marrow mononuclear cells versus mesenchymal stem cells from adipose tissue on bone healing in an Old World primate: can this be extrapolated to humans?
E. Branco et al · Universidade Federal de Minas Gerais, Escola de Veterinária · ISSN 1678-4162
ABSTRACT In veterinary medicine, the cell therapy is still unexplored and there are many unanswered questions that researchers tend to extrapolate to humans in an attempt to treat certain injuries. Investigating this sub...
LCC LCC:Animal cultureIdioma Inglés
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Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma-Treatment Modalities
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Articolo
Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma-Treatment Modalities
Zisis Vasileios et al · Balkan Stomatological Society · 2021 · ISSN 2335-0245
Head and neck squamous cell carcinoma (HNSCC) belongs to the most frequent cancer subtypes in the world. Mutations due to genetic and chromosomal instability, syndromes such as Fanconi anemia and the Bloom syndrome, envi...
LCC TENDOkRlbnRpc3RyeQ~~Idioma Inglés
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Comparison of the chondrogenic differentiation potential of bone marrow mesenchymal stem cells between female and male Wistar rats
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Articolo
Comparison of the chondrogenic differentiation potential of bone marrow mesenchymal stem cells between female and male Wistar rats
L.P. Romão et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2024 · ISSN 1678-4162
ABSTRACT This study aimed to compare the chondrogenic differentiation potential between bone marrow mesenchymal stem cells from female (fBMSCs) and male (mBMSCs) Wistar rats. For this purpose, female and male BMSCs were ...
LCC LCC:Animal cultureIdioma Inglés
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Células-tronco mononucleares autólogas e proteína óssea morfogenética na cicatrização de defeitos tibiais experimentalmente induzidos em cães Autologue mononuclear stem cells and morphogenetic bone protein in experimentally induced tibial defect healing in dogs
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Articolo
Células-tronco mononucleares autólogas e proteína óssea morfogenética na cicatrização de defeitos tibiais experimentalmente induzidos em cães Autologue mononuclear stem cells and morphogenetic bone protein in experimentally induced tibial defect healing in dogs
G.K. Oliveira et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2010 · ISSN 0102-0935
Avaliou-se a utilização de células-tronco mononucleares (CTM) na cicatrização de defeito ósseo experimental como alternativa aos métodos convencionais, analisando-se o tempo de evolução cicatricial e a presença...
LCC LCC:Animal cultureIdioma Inglés
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DS96432529 enhances osteogenic differentiation and mitigates inflammatory damage in periodontal ligament stem cells involving mitophagy-related processes
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Articolo
DS96432529 enhances osteogenic differentiation and mitigates inflammatory damage in periodontal ligament stem cells involving mitophagy-related processes
Haipeng He et al · BMC · 2026 · ISSN 1757-6512
Abstract Aim Periodontitis can impair the osteogenic function of periodontal ligament stem cells (PDLSCs), thereby compromising their capacity for periodontal tissue regeneration. In this study, we explored the impact of...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; TENDOkJpb2NoZW1pc3RyeQ~~Idioma Inglés
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Enterococcus faecalis biofilm removal efficacy, cytotoxicity and alkaline phosphatase activity on stem cells after the application of conventional medicaments and novel hydrogels used in regenerative endodontics
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Articolo
Enterococcus faecalis biofilm removal efficacy, cytotoxicity and alkaline phosphatase activity on stem cells after the application of conventional medicaments and novel hydrogels used in regenerative endodontics
Adem Öztürk et al · BMC · 2026 · ISSN 1472-6831
Abstract Background To compare the antibacterial activity of conventional intracanal medicaments used in regenerative endodontic treatment (TAP, DAP, Ca(OH)₂, CHX gel) with novel hydrogel-based formulations (chitosan, ...
LCC TENDOkRlbnRpc3RyeQ~~Idioma Inglés
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Exosomes from human urine-derived stem cells in porcine urethral scaffold construction
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Articolo
Exosomes from human urine-derived stem cells in porcine urethral scaffold construction
Zhang Kai-Yue et al · De Gruyter · 2026 · ISSN 2391-5412
This study aims to examine the role of exosomes derived from human urine-derived stem cells (hUSCs-Exo) in the in vitro construction of a composite structure comprising hUSCs and a porcine urethral decellularized matrix...
LCC LCC:Biology (General)Idioma Inglés
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Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis
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Articolo
Extracellular vesicles derived from live or apoptotic mesenchymal stem cells: comparison of the effects of two extracellular vesicles on liver fibrosis
Ruobing Ju et al · BMC · 2026 · ISSN 1471-230X
Abstract Background Mesenchymal stem cells (MSCs) have become a promising treatment of liver fibrosis which is a key process in liver diseases. Recent studies have shown that transplanted MSCs undergo rapid apoptosis and...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma Inglés
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Immunophenotyping, plasticity tests and nanotagging of stem cells derived from adipose tissue of wild rodent agouti (Dasyprocta prymnolopha)
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Articolo
Immunophenotyping, plasticity tests and nanotagging of stem cells derived from adipose tissue of wild rodent agouti (Dasyprocta prymnolopha)
A.R. Rocha et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2019 · ISSN 1678-4162
ABSTRACT There is a growing interest in the study of unspecialized mesenchymal stem cells, for there are still some discussions about their in vitro behavior. Regenerative medicine is a science undergoing improvement whi...
LCC LCC:Animal cultureIdioma Inglés
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Periodontal ligament stem cells-loaded photocrosslinking GelMA/PEGDA scaffolds for periodontal bone regeneration
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Articolo
Periodontal ligament stem cells-loaded photocrosslinking GelMA/PEGDA scaffolds for periodontal bone regeneration
Bei Gao et al · BMC · 2026 · ISSN 1472-6750
Abstract Background Matrix stiffness is a key feature of the mechanical microenvironment. Periodontal tissue is a multicomponent structure composed of cementum, periodontal ligament, and alveolar bone, and is essential f...
LCC TENDOkJpb3RlY2hub2xvZ3k~Idioma Inglés
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Protein Kinase R-like Endoplasmic Reticulum Kinase-Mediated ER-Mitochondria Coupling Regulates Odontogenic Differentiation of Human Dental Pulp Stem Cells Under Inflammatory Stimuli
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Articolo
Protein Kinase R-like Endoplasmic Reticulum Kinase-Mediated ER-Mitochondria Coupling Regulates Odontogenic Differentiation of Human Dental Pulp Stem Cells Under Inflammatory Stimuli
Yiqing Wang et al · Elsevier · 2026 · ISSN 0020-6539
Introduction and aims: Human dental pulp stem cells (hDPSCs) play pivotal roles in the regeneration of pulp-dentin complex, yet their odontogenic differentiation is critically modulated by the inflammatory microenvironme...
LCC TENDOkRlbnRpc3RyeQ~~Idioma Inglés
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Proteomic Profiling of PTEN Inhibition on Periodontal Ligament Stem Cells
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Articolo
Proteomic Profiling of PTEN Inhibition on Periodontal Ligament Stem Cells
Suphalak Phothichailert et al · Elsevier · 2026 · ISSN 0020-6539
Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...
LCC TENDOkRlbnRpc3RyeQ~~Idioma Inglés
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Renal Stem Cells
Articolo
Articolo
Renal Stem Cells
Egemen KAYA et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440
Kidney diseases, related to high morbidity and mortality, are one of the diseases that should be primarily investigated. Development of acute and chronic kidney diseasesis due to lack of functioning renal repair mechan...
LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma Inglés
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Self-organized anteroposterior regionalization of early midbrain and hindbrain/spinal cords using micropatterned human pluripotent stem cells
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Articolo
Self-organized anteroposterior regionalization of early midbrain and hindbrain/spinal cords using micropatterned human pluripotent stem cells
Tianfa Xie et al · Elsevier · 2026 · ISSN 2472-6303
Anterior-posterior (AP) spatial regionalization is crucial for central nervous system development. Previous studies suggest that morphogen gradients can induce AP patterning in animal and organoid models. While self-orga...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma Inglés
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Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence
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Articolo
Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence
Videla Richardson, Guillermo Agustín et al · International Society of Neuropathology · 2015 · ISSN 1015-6305
Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined. In this study, we established several GSC-enri...
Idioma Inglés
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The Cell Cycle Inhibitors p21 Cip1 and p27 Kip1 Control Proliferation but Enhance DNA Damage Resistance of Glioma Stem Cells
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Articolo
The Cell Cycle Inhibitors p21 Cip1 and p27 Kip1 Control Proliferation but Enhance DNA Damage Resistance of Glioma Stem Cells
Morris Hanon, Olivia et al · Elsevier · 2017 · ISSN 1476-5586
High-grade gliomas are the most prevalent and lethal primary brain tumors. They display a hierarchical arrangement with a population of self-renewing and highly tumorigenic cells called cancer stemcells. These cells are ...
Idioma Inglés
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The importance and use of stem cells in dermatology
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Articolo
The importance and use of stem cells in dermatology
Agnieszka Owczarczyk-Saczonek et al · Termedia Publishing House · 2016 · ISSN 0033-2526
Stem cells are capable of self-renewal of their population and differentiation into specialized cells. There are several “niches” in the skin: 1) interfollicular stem cells – responsible for skin regeneration after...
LCC LCC:Medicine; LCC:DermatologyIdioma Inglés
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Therapeutic Potential in Wound Healing of Allogeneic Use of Equine Umbilical Cord Mesenchymal Stem Cells
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Articolo
Therapeutic Potential in Wound Healing of Allogeneic Use of Equine Umbilical Cord Mesenchymal Stem Cells
Iribarne, Ailen et al · Molecular Diversity Preservation International · 2024 · ISSN 1422-0067
Wound healing after skin injury is a complex process, particularly in equines where leg wounds are prevalent and their repair is complicated due to the anatomical characteristics. Conventional treatments are not effectiv...
Idioma Inglés
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Treatment of chronic immunomediated thrombocytopenia with mesenquimal stem cells in dog - case report
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Articolo
Treatment of chronic immunomediated thrombocytopenia with mesenquimal stem cells in dog - case report
P.R. Santi et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2023 · ISSN 1678-4162
ABSTRACT Immunomediated thrombocytopenia is a systemic metabolic disorder in which the platelet count falls below reference values, as the patient's immune system destroys them. The main clinical signs in thrombocytopeni...
LCC LCC:Animal cultureIdioma Inglés
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Visceral and subcutaneous adipose stem cells modulate colorectal cancer cell progression: direct and indirect contact distinctly accelerate tumor aggressiveness
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Articolo
Visceral and subcutaneous adipose stem cells modulate colorectal cancer cell progression: direct and indirect contact distinctly accelerate tumor aggressiveness
Mikołaj Domagalski et al · BMC · 2026 · ISSN 1528-3658
Abstract Background Adipose tissue is increasingly recognized as an important component of the tumor microenvironment of colorectal cancer (CRC) and actively contributes to the progression of the disease. Adipose stem ce...
LCC LCC:Therapeutics. Pharmacology; TENDOkJpb2NoZW1pc3RyeQ~~Idioma Inglés
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Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo
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Articolo
Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo
Naujok, Ortwin et al · John Wiley & Sons Ltd · 2009 · ISSN 1520-7552
Background: Embryonic stem (ES) cells have the potential to produce unlimited numbers of surrogate insulin-producing cells for cell replacement therapy of type 1 diabetes mellitus. The impact of the in vivo environment o...
Idioma Inglés
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