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In this work the effects of topic use of Brazilian green propolis gel in the contraction of wounds performed in rat s skin was evaluated. In ten female Wistar rats were done four wounds in dorsal region. Two wounds in ea...

This study aimed to evaluate the action of Brazilian green propolis (5%) topic use on cutaneous wound healing in rats, by inflammatory cell counting. Ten Wistar rats were separated in groups 24 h and 72 h, were trichotom...

This study aimed to evaluate the effect of a diclofenac diethylammonium gel 10 mg/g (DD) on acute phase of ligature induced periodontitis model in rats. Experimental Periodontitis Disease (EPD) was induced in 30 Wistar r...

La actividad anti-úlcera de extractos secos nebulizados de M. ilicifolia fue ensayada por vía oral en ratas machos Wistar. La indometacina fue usada como sustancia ulcerogénica y la cimetidina como sustancia control. ...

Seveal Baccharis species known as "carquejas" are used in Argentinean folk medicine as phytotherapics. B. crispa, B. articulata, B. trimera, B. sagittalis and B. triangularis have been evaluated for their choleretic acti...

Los radicales libres producen efectos dañinos sobre las moléculas diana, como una incrementada peroxidación de lípidos (PL), proteínas y del ADN, lo cual puede ser inhibido o reducido por sustancias antioxidantes. E...

Se compararon dos métodos de diagnóstico de Trichinellosis: triquinoscopía y digestión artificial. Se examinaron los músculos de 35 ratas Wistar infectadas per os con inóculos (10, 50, 100, 200, 300, 400, 500 larva...

The comparative antidepressant activity of the extracts of Hypericum perforatum and Rosmarinus officinalis using animal models of depression were evaluated. The herbal extracts of Hypericum perforatum (20 mg/kg/p.o.), Ro...

The present study was undertaken to evaluate the comparative antidepressant activity of Ocimum sanctum (OS) and imipramine using animal models of depression. Imipramine (15 mg/kg/i.p) and herbal extract of OS (500 mg/kg/...

En el presente estudio se evaluó el efecto del tratamiento con extracto diclorometánico (DcM) del tallo de Kielmeyera coriacea en el catabolismo hepático da L-alanina (5 mM) em ratas Wistar machos y hembras. Las ratas...

We studied if monocrotaline (MCT) portal hypertensive model modifies blood-brain barrier (BBB) condition. Male Wistar rats were used: Group MCT injected i.p. with MCT (60 mg/kg of body weight) and Group Sham (GS) with sa...

Obesity was induced by high fat diet (30 % fat by weight). Wistar rats of 225-250 g were kept on high fat diet to induce obesity for 90 days. Sodium tungstate (2 mg/ml, in drinking water) was administered for 90 days. ...

Diabetes mellitus is a metabolic disease associated to oxidative stress. In this work, the hypoglycaemic and antioxidant effect of an extract of Physalis peruviana fruits in an experimental diabetes model was evaluated. ...

Se determinó la composición química y la mutagenicidad de los aceites esenciales obtenidos de las hojas del Ocimum selloi Benth, perteneciente a la familia Lamiaceae, nativos de la región sur de Brasil. Para el estud...

The total phenolic content and in vitro and in vivo antioxidant activities of the whole plants of Hedyotis puberula (G. Don) R.Br. ex Arn. were appraised. The methanol extract of the plant contained higher levels of to...

The purpose of this study was to improve the meloxicam dissolution rate through its formulation into liquisolid compacts and then to evaluate the in vitro and in vivo performance of the prepared liquisolid compacts. Di...

The present study was designed to assess the influence of ACE inhibitors on the electrocardiograph of acute renal hypertensive rats. Acute Renal Hypertension (ARH) was induced in healthy Wistar male rats by clamping/occl...

High fat diet (30 % fat) was used to induce obesity in rats. Male wistar rats were kept at high fat diet for 90 days and subjected to partial abdominal aortic constriction (PAAC) at 62nd day and continued upto 90th day...

The present study utilizes approach of solid dispersions (SDs) to improve dissolution rate of Gliclazide (GLZ); a poorly water soluble anti-diabetic drug. Formulations were prepared by solvent evaporation and melt disper...

Diuretic activity of five medicinal plants (Cassia alata L., Zanthoxylum fagara L., Nectandra coriacea Sw, Costus pictus D. Don, and Persea americana Miller) used by Cuban population was assessed. Plants decoctions (30 %...

The aim of the present study was to investigate the role of liver in progression of insulin resistance in relation to IGF-I levels in rats with acute hepatotoxicity, induced by carbon tetrachloride (CCl4) and acetaminoph...

This study evaluated the effect of Cordia verbenacea essential oil (CV) and glycolic acid 70 % (GA), isolated and associated, on Wistar rats back skin. A base gel was added to 2 % of CV and/or 10 % of GA, thus forming ...

En el presente trabajo se describe y valida parcialmente un método simple y con una adecuada sensiblilidad para la determinación de cinarina en plasma. Este método fue utilizado para determinar el perfil farmacocinét...