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Immunoaffinity chromatography (IAC) has a wide application in protein purification. The aim of the study was to investigate the influence of five operational factors on an IAC procedure to purify a yeast derived-Hepatiti...

The viability of employing flow analysis coupled to Fourier transform infrared spectroscopy (FA-FTIR) as a useful tool for quantitative measuring of magnesium sulphate in pharmaceuticals was explored, developed and valid...

The aim of this work was to develop clozapine tablets that can be classified as a pharmaceutical equivalent to a reference brand product. Tablets were produced by direct compression and dissolution tests were realized ...

Cabergoline (CAB) is a synthetic ergoline dopamine agonist with high affinity to D2 receptors, thus used for the treatment of Parkinson's patients and hyperprolactinemia disorders. In this study, simple, fast, reliable a...

Several colorimetric and chromatographic methods have been used for the identification and quantification of methyldopa (MA) in pharmaceutical formulations and clinical samples. However, these methods are time- and reage...

Se describe un método rápido, simple, económico y preciso para la determinación de la fluoroquinona gatifloxacina en comprimidos. El procedimiento está basado en el uso de dosaje volumétrico en un medio no acuoso ...

This work describes the evaluation of a Pharmaceutical Care (PC) service in Belo Horizonte. It is an observational, longitudinal, non concurrent study, addressed to patients attended at the School Pharmacy of the Newton ...

The objective of this paper was to develop a high performance liquid chromatography with diode array detection both for chromatographic fingerprint and simultaneous determination of twelve analytes of Shuang-Huang-Lian (...

A micellar liquid chromatographic method was developed for the simultaneous analysis of a binary mixture of norfloxacin and tinidazole (NOR and TIN) in dosage forms and human plasma. The analysis was carried out using a ...

Chitosan is increasingly used as an alternative to synthetic polymers due to its water solubility, biodegradability, and biological activity. In this work, chitosan samples from three suppliers were evaluated and charact...

A study was carried out to analyze the factors associated with drug spending by the elderly population in Belo Horizonte, Brazil. Data were obtained using a household survey of 667 communitydwelling persons aged 60 years...

La Flutamida es un antiandrógeno potente usado para el tratameinto del cáncer de próstata. Se presenta aquí un método simple, sensible y seguro de cromatografía de alta resolución (HPLC) para la determinación cua...

En el presente trabajo se estudió la descomposición térmica del efavirenz (EFZ), un no-nucleótido que es inhibidor de la transcriptasa reversa de prolongada vida media, utilizando calorimetría diferencial de barrido...

Sibutramine hydrochloride monohydrate (SHM) has been widely used for the management of overweight and obesity. However, more restrict data have been regarded about in vitro dissolution profile of SHM from pharmaceutical ...

A capillary zone electrophoresis (CZE) method has been developed for the analysis of cabergoline in its pharmaceutical preparations. Optimized analysis conditions for cabergoline analysis were performed using 110 mM pH 5...

El análisis estadístico, así como el diseño experimental, el análisis de regresión y el análisis multi-respuesta son potentes herramientas para la caracterización y la optimización de los procesos farmacéuticos...

En el presente trabajo se desarrolló y validó un método por cromatografía líquida de alta eficacia (CLAE) para los estudios de disolución y la estimación cuantitativa de valdecoxib en tabletas y en el ingrediente ...

Los medicamentos genéricos de calidad y bajo costo están disponibles para la población brasilera desde 1999, cuando se instituyó la Política de Medicamentos Genéricos de Brasil. Este artículo presenta los criterio...

A new simple, rapid and reproducible high performance thin layer chromatographic method has been developed and validated for the analysis of granisetron hydrochloride (GSH) in bulk drug and from pharmaceutical formulatio...

The use of biosensors based on laccase is an interesting alternative for monitoring phenolic compounds in pharmaceutical and environmental analysis. The detection and determination of acetaminophen in pharmaceutical samp...

Glechon spathulata Benth. (Lamiaceae) is a native plant in Brazil popularly known as "mangerona-do-campo". This plant is a perennial sub-shrub with aromatic leaves used in South America as a condiment and in traditional ...

Choline citrate (CC) and acetylmethionine (AM) are lipotropic drugs used in several pharmaceutical formulations. The objective of this research was to develop and validate a high performance liquid chromatographic (HPLC...