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La actividad anti-úlcera de extractos secos nebulizados de M. ilicifolia fue ensayada por vía oral en ratas machos Wistar. La indometacina fue usada como sustancia ulcerogénica y la cimetidina como sustancia control. ...

The aim of this study was to validate an agar diffusion method through the parameters linearity, precision and accuracy, to quantify apramycin in soluble powder. The calibration curve of apramycin was constructed by plo...

The quality control of herbal drugs and their intermediates is essential, especially when they are used as feedstock for medicine development. This study aimed at applying the methodologies established by Brazilian legis...

Raman spectroscopy in combination with partial least-squares (PLS) regression method was developed for sulphamethoxazole (SMZ) and trimethoprim (TMP) simultaneous determination in powder mixtures. The calibration set was...

Some theoretical studies abouth dynamic compression of powder aluminum are described. 3-D Finite elements of 27nodes are employed in spherical construction by flat circular plates. The first step is the testing of a prov...

The effects of drying air inlet temperature (IT) and concentration of Aerosil® 200 (CA) on several properties of spray-dried Apeiba tibourbou extracts were investigated following a 32 full factorial design. Powder recov...

The great variety of excipients to which we have access thanks the globalization gives rise to the necessity to evaluate their functionality, currently the pharmaceutical performance of croscarmellose and carmacel as tab...

The aim of the present investigation is to improve the dissolution of poorly water soluble drug valsartan by preparing solid dispersions and also to evaluate the effect of different inert carriers on flow properties of s...

Fenofibrate is more effective drug as compared to other fibrates. But low bioavailability of it is due to its poor aqueous solubility. The purpose of present study was to improve fenofibrate dissolution through its formu...

Spherical crystallization (SC) is a promising alternative for improiving micromeritic properties and dissolution rate of active pharmaceutical ingredients. In the present work spherical agglomerates of carvedilol (CAR) w...

An evaluation of the extraction of pharmacological markers (kavalactones) of the plant species Piper methysticum (kava-kava) was conducted. Capsules containing ground kava-kava were submitted to an in vitro method using ...