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Quantitative Structure Activity Relationship (QSAR) studies were carried out for a series of 16 compounds which acts as ligands for PPAR-γ receptor. TSAR software was used to identify the essential structural and physic...

Diuretics are an attractive class of drugs for the treatment of various disorders and in combination with some cardiovascular drugs. In the present work, 2D and 3D quantitative structure-activity relationship studies hav...

The objective of the present study was to develop an oral timed-released press-coated tablet containing theophylline as a model drug. A D-optimal design of experiment was employed to systematically study the effect of te...

En el presente trabajo se desarrolló y validó un método por cromatografía líquida de alta eficacia (CLAE) para los estudios de disolución y la estimación cuantitativa de valdecoxib en tabletas y en el ingrediente ...

Cylin dependent kinases (CDKs) have emerged as novel mechanistic target due to their direct involvement in underlying genetic changes during the cancerous state. In order to identify the essential physiochemical paramete...

The purpose of the present study was to develop and optimize floating-bioadhesive bilayer gastroretentive drug delivery system (GRDDS) exhibiting a unique combination of floatation and bioadhesion to prolong residence ...

New fast liquid chromatographic and capillary zone electrophoresis methods were developed and validated for simultaneous determination of atenolol and chlortalidone in combined dose tablets. The reversed phase HPLC metho...

To research optimization possibilities in supercritical ORC processes for geothermal power production the Modular low-Temperature Circuit Karlsruhe (MoNiKa) was built at Campus North of the Karlsruhe Institute of Technol...

Two methods for simultaneous estimation of acetaminophen, chlorpheniramine maleate and caffeine in pure and tablet dosage form have been developed. Method I employs formation and solving of simultaneous equation using ...