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Abstract Biological soft tissues manipulation, including conventional (mechanical) and nonconventional (laser, waterjet and ultrasonic) processes, is critically required in most surgical innervations. However, the soft t...

The valorization of carbon dioxide (CO₂)-rich streams is emerging as a key pillar of a circular, climate-neutral bioeconomy. Biological platforms such as microalgae cultivation, anaerobic fermentation and microbial pol...

This study analyzes different factors that affect the success of artificial insemination (AI) of cows of small farmers inserted in a program of productive and genetic improvement in one region in Chile. The success of AI...

Flow cytometry has become an important tool in the fields of veterinary, medicine, and biological sciences in general. However, in the introductory and even in advanced university degree courses, students do not have man...

Abstract Chimeric antigen receptor (CAR) T cell therapies have achieved clinical success in autologous treatment of hematological malignancies. However, their broader application remains limited. Beyond the biological ch...

Abstract The search for high-efficiency antimicrobial nanomaterials has intensified due to the escalating threat of antibiotic resistance. In this study, titanium dioxide nanoparticles (TiO2 NPs) were synthesized using a...

Computer-aided drug discovery and design involve the use of information technologies to identify and develop, on a rational ground, chemical compounds that align a set of desired physicochemical and biological properties...

Brain–computer interfaces (BCIs) based on motor imagery (MI) provide a transformative direct communication pathway for patients with severe motor disabilities. However, the high inter-subject variability and non-statio...

Although vaccination remains one of the most impactful interventions in contemporary public health, with consistent and widely documented reductions in morbidity and mortality, the traditional empirical development of va...

Introduction According to modern scholars (N. Maslova, B. Astafiev), one of the important reasons for the global planetary crisis, including modern educational system in particular, is violation of the conformity of natu...

Background: Barrett's esophagus (BE) represents a critical precancerous lesion arising from chronic gastroesophageal reflux disease (GERD), with significant risk of progression to esophageal adenocarcinoma. Despite advan...

This article provides a contribution to the debate about the processes of circulation of knowledge and meanings among experts and laymen regarding the status of human embryos in Portugal. It weighs up the expectations an...

Abstract Chronic pain is a multifactorial condition often accompanied by comorbidities such as anxiety, depression, and cardiovascular dysfunction. Traditional injury-based models have provided valuable mechanistic insig...

Sepsis remains one of the most complex and lethal syndromes in pediatric critical care, driven by dysregulated and heterogeneous host responses to infection. Despite decades of biomarker research, few biomarkers have bee...

Heavy metal pollution has become a major global concern due to its serious threats to ecosystem stability and public health. Although significant progress has been achieved in physical, chemical, and biological remediati...

Abstract Alzheimer’s disease (AD) is a prevalent and progressive neurodegenerative disease characterized by behavioral abnormalities, memory loss, and cognitive decline, presenting significant challenges for early diag...

On-chip nanophotonic devices are a class of devices capable of controlling light on a chip to realize performance advantages over ordinary building blocks of integrated photonics. These ultra-fast and low-power nanoscale...

Produced water, generated as a byproduct of oil and gas extraction, is a complex mixture characterized by high salinity and the presence of hydrocarbons, heavy metals, salts, and production-related chemicals. Its large v...

Extracellular vesicles (EVs) are complex biological nanoparticles endogenously secreted by all eukaryotic cells. EVs carry a specific molecular cargo of proteins, lipids, and nucleic acids derived from cells of origin an...

Abstract Titanium and its alloys have been widely applied in many biomedical fields because of its excellent mechanical properties, corrosion resistance and good biocompatibility. However, problems such as rejection, she...

Sensorineural hearing loss (SNHL) is a major cause of disability worldwide, characterized by irreversible damage to cochlear hair cells and spiral ganglion neurons. Current treatments such as hearing aids and cochlear im...

Background: The release of micro- and nanoplastics (MNPs) from tea bags during brewing is a significant, recently identified source of potential human exposure. This systematic review collected global research published ...

Abstract Psychiatric disorders place considerable burden on individuals and on public health. Funding for research in psychiatry is less than ideal, but even so high quality research is being conducted at many centers. H...