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The temporal dynamics in biological systems displays a wide range of behaviors, from periodic oscillations, as in rhythms, bursts, long-range (fractal) correlations, chaotic dynamics up to brown and white noise. Herein, ...

Abstract Chronic wounds represent a longstanding clinical problem due to impaired angiogenesis due to insufficient activation of vascular endothelial growth factor receptor 2 (VEGFR2). In this investigation, we used comp...

The rapid expansion of whole-genome sequencing (WGS) has highlighted the important contribution of noncoding variants to human disease, yet their pathogenic mechanisms remain difficult to resolve. Traditional statistical...

The growing demand for intensive artificial intelligence applications, such as deep neural networks and Large Language Models (LLMs), has driven the creation of architecture extensions and accelerators for matrix multipl...

The remaining calcium hydroxide (Ca(OH)2) medicaments in the root canal wall can block the penetration of filling medicaments to the dentine tubule and cause the failure in the root canal treatment. One of the ways in cl...

ABSTRACT The rapid advancement of medicine, fueled by big data and interdisciplinary research, has significantly transformed the landscape of computational oncology research. In this evolving environment, effective time ...

Abstract Early and reliable smoke detection is critical for preventing fire-related disasters, safeguarding human lives, and ensuring infrastructure safety. Conventional sensor-based systems, however, are often constrain...

Computational modeling of protein-protein interactions (PPIs) is a high priority because it is essential for understanding nearly all cellular functions and for addressing the limitations of time-consuming experimental m...

Data quality varies dramatically from source to source, even within the same domain. Given these challenges, data source selection has emerged as a crucial step in information integration. It demands efficient and scalab...

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cholinergic dysfunction, making acetylcholinesterase (AChE) a key therapeutic target. Although Garcinia kola has been widely reported ...

Salinity distribution is a critical determinant in the management of water resources and the protection of ecological integrity in coastal regions, drawing particular concerns in the context of increasing saltwater intru...

Abstract A Schiff base ligand L 1 was synthesized via the condensation reaction between from 2-hydroxy-1-naphthaldehyde and 4-methoxyaniline. This Schiff base was employed for the preparation of metal complexes of type [...

Abstract In this work, a new method employs Bioinspired Computational (BIC) optimization from the genetic algorithm, bat algorithm, and flower pollination algorithm. Robust and accurate modeling of the input parameters a...

Zernike moments are well-suited for unmanned aerial vehicle scene matching because of their rotation invariance and robustness to noise. However, their high computational complexity poses challenges for meeting the real-...

Abstract Background N6-methyladenosine ( $$m^{6}A$$ ) plays a crucial role in enriching RNA functional and genetic information. While deep learning has advanced $$m^{6}A$$ site identification, current state-of-the-art me...

Introduction. The performance reliability of electric vehicles (EVs) is an important factor in evaluating their suitability for widespread adoption. The reliability and lifespan of an EV depend on several critical factor...

Given a positive integer k, the {k}-packing function problem ({k}PF) is to find in a given graph G, a function f of maximum weight that assigns a non-negative integer to the vertices of G in such a way that the sum of f(...

Abstract Alkaline water electrolysis represents a promising pathway for green hydrogen production, yet comprehensive multi-physics simulation remains computationally prohibitive for practical design optimization. This st...

Abstract This study presents a computational investigation into the aerodynamic and thermal performance enhancement of a solar chimney power plant (SCPP) through the integration of wavy geometries along the collector roo...

The menstrual cycle affects many aspects of female physiology, from the immune system to behavioral and emotional regulation. It is unclear however if these physiological changes are reflected in everyday, naturalistic l...

An existing hybrid MPI-OpenMP scheme is augmented with a CUDA-based fine grain parallelization approach for multidimensional distributed Fourier transforms, in a well-characterized pseudospectral fluid turbulence code. B...

This work studies the performance of two open-source CFD codes, OpenFOAM and MFiX, to address bubbling fluidized bed system at different temperature and heat transfer conditions. Both codes are used to predict two parame...

Abstract Computational efficiency and accuracy always conflict with each other in molecular dynamics (MD) simulations. How to enhance the computational efficiency and keep accuracy at the same time is concerned by each c...

Abstract Advances in artificial intelligence (AI) and multi-omics integration are reshaping precision oncology by enabling deeper mechanistic understanding, improved characterization of tumor heterogeneity, and the accel...