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Abstract Background Early detection of renal involvement in ANCA-associated vasculitis (AAV) is crucial, as functional changes often precede anatomical damage. Current diagnostic standards, such as the measurement of ser...

Tsung-Kun Lin,1,2,* Chih-Feng Chang,3,* Gwo-Ping Jong4,5 1Department of Pharmacy, Tri-Service General Hospital, Taipei, Taiwan, Republic of China; 2School of Pharmacy, National Defense Medical University,...

Patients treated with hemodialysis are predisposed to infections. Catheter-related infections are the most common infections in patients who have a central venous hemodialysis catheter. These infections may lead to bacte...

Introduction . Urticarial vasculitis is a subtype of cutaneous leukocytoclastic vasculitis. The disease often accompanies systemic disorders, including hematologic malignancies, connective tissue diseases, and infectious...

Granulomatosis with polyangiitis (GPA) is a chronic systemic disease that is characterized by granulomatous inflammation of the upper and lower respiratory tract accompanied by systemic vasculitis of small and medium-siz...

Kidney may be affected by many types of systemic disease and play an important role on the diagnosis and treatment of these systemic illnesses. Many immuncomplex diseases like systemic lupus 'erythematosus (SLE), Henoch ...

Abstract Background Vascular endothelial inflammation is a key pathological process underlying various inflammatory vascular conditions, which can lead to severe cardiovascular complications. Shexiang Tongxin Dropping Pi...

Goodpasture’s syndrome is a rare autoimmune disease in which anti-glomerular basement membrane antibodies damage the glomerular and alveolar basement membrane. Its relapse is very rare, compared to other pulmonary-rena...

Abstract Background Traditionally, 6‐month courses of prednisolone are used to treat steroid‐responsive meningitis‐arteritis (SRMA), but this medication is associated with adverse effects that can lead to poor qual...

Abstract Background Acute hepatic porphyria (AHP) is a heme metabolism disorder characterized by acute abdominal pain episodes, with diagnostic delays and misdiagnosis due to heterogeneous presentations and symptom overl...

Wegener’s Granulomatosis is a multisystemic granulomatous inflammation of small vessels that typically effects the kidney, skin, joints and lower and upper airway tracts. Because of the multisystemic involvement, the s...

Henoch-Schönlein (HSP) purpura is a small vessel vasculitis affecting the skin, joint, gut, and kidneys. Azathioprine is a drug used to prevent rejection after solid organ transplantation and treat autoimmune-inflammatu...

Classic polyarteritis nodosa (cPAN) is a systemic necrotizing vasculitis of medium-sized muscular arteries. Glomerular involvement is not expected in the course of cPAN. Herein, we describe a case of cPAN with glomerular...

Abstract Background The newly discovered Treg subset (CLA+ Tregs) expressing cutaneous lymphocyte-associated antigen is associated with inflammatory conditions. This study elucidated the role of CLA+ Tregs in rheumatoid ...

IntroductionChronic spontaneous urticaria (CSU) is a clinical diagnosis managed according to American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) guide...

ABSTRACT Background/Aim Most patients with proteinuria are considered to have typical diabetic nephropathy (DN). However, when proteinuria occurs without diabetic retinopathy, with hematuria, or persists despite strict g...

Objective This study aimed to describe the clinical and neuroimaging characteristics and 120-day outcomes in neuropsychiatric systemic lupus erythematosus patients. Methods This prospective study involved 32 patients wit...

Abstract Background Understanding of equine herpesvirus‐1 (EHV‐1) myeloencephalopathy (EHM) is complicated by disparities among studies. Objective Compare clinical findings and outcome in horses involved in 2 recent ...

Highest prevalence of all antineutrophil cytoplasmic antibody associated systemic vasculitides is the Wegener granulomatosis, and it’s typically characterized by a necrotizing granulomatous vasculitis of the respirator...

Henoch-Schönlein purpura (HSP) is a vasculitis characterized by purpuric rash, arthritis, nephritis and gastrointestinal symptoms and it is generally seen in children. We report here a case of crescentic HSP nephritis w...

Microscopic polyangiitis is small vessel necrotizing vasculitis involving the kidney, sometimes skin, and lung. This disease is characterized by the presence of an ANCA and few or no immune deposits in involved vessels. ...

Abstract Background Dynamics of infection by Bartonella and Rickettsia species, which are epidemiologically associated in dogs, have not been explored in a controlled setting. Objectives Describe an outbreak investigatio...

Deficiency of adenosine deaminase 2 (DADA2) was identified in 2014 as a novel inborn error of immunity caused by biallelic pathogenic variants in ADA2. DADA2 patients express two predominant clinical phenotypes: (1) auto...

Genetic alteration of the genes of cytoskeletal regulatory proteins (e.g., actin-related protein complex-1 [ARPC1]) results in severe immune and hematological defects. ARPC1B deficiency (ARPC1BD) is an immune-actinopathy...