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The effects of cannabinoids in mitochondria after acute oxidative stress insult are not fully established. We investigated the ability of CP55,940 and JWH-015 to scavenge reactive oxygen species and their effect on mitoc...

Oxidative stress (OS), derived from an imbalance between reactive oxygen species (ROS) accumulation and impaired antioxidant defense, is a recognized cause of atherothrombosis, through a complex interaction between low-g...

ABSTRACT This study aimed to evaluate oxidative stress parameters in bucking bulls submitted to acupuncture by measuring total anti oxidizing capacity (TAC-ABTS; TAC-ABTS+HRP), total oxidizing capacity (TOC; TBARS), albu...

Background/ObjectiveCisplatin is a popular platinum-containing chemotherapeutic agent that has been used clinically since the 1970s to manage a wide range of hematologic and solid tumors. However, its therapeutic purpose...

Chlorfenapyr (CHL) is a widely used insecticide whose expanding application raises concerns about cardiotoxicity following both acute poisoning and chronic environmental exposure. The mechanisms underlying its cardiac in...

Foram avaliados o desempenho produtivo e os parâmetros fisiológicos de tilápias-do-nilo alimentadas, durante 112 dias, com dietas preparatórias para o inverno, formuladas com diferentes níveis de lipídeo e vitamina...

Kecelakaan lalu lintas sebagai pengalaman yang menyakitkan dapat menyebabkan berbagai bentuk kerugian psikologis, seperti trauma, Acute Stress Disorder, Post-Traumatic Stress Disorder, gejala-gejala depresif, bahkan penu...

ABSTRACT Background and Aims Human metapneumovirus (hMPV) is a leading cause of acute respiratory tract infections, particularly in children, older adults, and individuals with immunocompromising conditions. Despite incr...

ABSTRACT Retinal ganglion cell (RGC) degeneration represents a cardinal etiology of irreversible vision loss in glaucoma, where efficacious regenerative therapies remain scarce. RGC replacement therapy holds promise for ...

Introduction Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may cause stress-induced transient acute cardiac dysfunction through myocardial stunning, in the form of exacerbation-triggered Takotsubo ...

We show that TANGO2 in mammalian cells localizes predominantly to mitochondria and partially at mitochondria sites juxtaposed to lipid droplets (LDs) and the endoplasmic reticulum. HepG2 cells and fibroblasts of patients...

Abstract Background In Hatay, Türkiye, which suffered extensive devastation from the earthquake of 2023, people were living in container cities during the recovery process. While the physical and psychological effects o...

To investigate the impact of acute energetic stress (acute HIIE and fasting) on ERRγ, PPARβ, NR1D1, NR4A1, and TFEB in human skeletal muscle.

Abstract The genomic locus that encodes the Leucine-rich repeat kinase 2 (LRRK2) gene is highly pleiotropic and associated with Parkinson’s disease (PD). Coding variants associated with risk of PD act as gain of functi...

Abstract In this study, we compared acute metabolic responses and barbell velocity loss (VL) during cluster set (CS) versus traditional set (TS) resistance exercise. Six strength‐trained individuals completed two rando...

Abstract Objective The study aimed to evaluate the hypoxia-induced brain injury and neuroprotective effects of pyrimidine and its derivative, arylvinylpyrimidine (AVP), in the freshwater catfish, Heteropneustes fossilis....

This study comprises two distinct but parallel investigations concerning Haemaphysalis longicornis in Korea: an exploratory ecological survey of vector density across 20 sites in 2023 and a laboratory-based screening of ...

BackgroundN-acetylcysteine (NAC) is a key precursor of glutathione (GSH), the lung’s principal antioxidant. First developed as a mucolytic, NAC is now recognized for broader antioxidant, anti-inflammatory, immunomodula...

Nanotechnology is growing at an exponential rate and will undoubtedly have both beneficial and toxicological impact and consequences on health and environment. Amphibians are being increasingly used for toxicity screenin...

The early postoperative period in infants following the correction of congenital heart defects is often accompanied by hemodynamic lability, systemic stress, and an acute-phase response, which may lead to transient organ...

Abstract Background Takotsubo syndrome (broken-heart syndrome) is considered a cardiac disorder typically associated with exposure to severe psychological or physical stress, and it clinically resembles acute coronary sy...

Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a chronic condition characterized by hepatic fat accumulation and systemic metabolic dysfunction. MASLD exhibits clear sex differenc...

Background and Literature ReviewHypereosinophilic syndrome (HES) is a rare, heterogeneous group of disorders defined by persistent hypereosinophilia (>1,500 cells/µL) with eosinophil-mediated end-organ damage. Its estim...

Exercise promotes neurogenesis and enhances memory consolidation while reducing the retention of aversive memories and anxiety-like behaviors. While our previous work found that acute exercise alters neurotransmitter con...