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113 resultados encontrados.

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Clinical presentation and treatment outcomes in a South African thrombotic thrombocytopenic purpura cohort with and without HIV
Artículo
Acceso abierto Artículo DOAJ
Clinical presentation and treatment outcomes in a South African thrombotic thrombocytopenic purpura cohort with and without HIV
Nokubonga Vundla et al · AOSIS · 2026 · ISSN 1608-9693
Background: HIV is the most common cause of secondary thrombotic thrombocytopenic purpura (TTP) in South Africa.  Objectives: To assess the clinical presentations and outcomes of patients treated for HIV-associated and...
LCC LCC:Public aspects of medicine; TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis
Artículo
Material complementario disponible Artículo DOAJ
Clinical utility of the lactate-to-albumin ratio for predicting mortality in elderly severe acute pancreatitis
Qingcheng Zhu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundElderly patients with severe acute pancreatitis (SAP) have high mortality, yet reliable early risk stratification tools remain limited. The lactate-to-albumin ratio (LAR) has emerged as a potential prognostic b...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Clinicopathological and prognostic significance of stromal maturity, tumour-infiltrating lymphocytes, and systemic environment in breast cancer
Artículo
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Clinicopathological and prognostic significance of stromal maturity, tumour-infiltrating lymphocytes, and systemic environment in breast cancer
Qing Guo et al · BMC · 2026 · ISSN 1746-1596
Abstract Background The tumour microenvironment and systemic inflammatory environment are related to the diagnosis, treatment and prognosis of various tumours. This study aimed to evaluate the clinicopathological signifi...
LCC TENDOlBhdGhvbG9neQ~~Idioma eng
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Comprehensive clinicopathological and prognostic analysis of primary pulmonary lymphoepithelial carcinoma: a retrospective cohort study
Artículo
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Comprehensive clinicopathological and prognostic analysis of primary pulmonary lymphoepithelial carcinoma: a retrospective cohort study
Meihong Yao et al · BMC · 2026 · ISSN 1746-1596
Abstract Background Primary pulmonary lymphoepithelial carcinoma (PPLEC) is an extremely rare subtype of lung squamous cell carcinoma (LUSC). This study aims to comprehensively characterize clinicopathological and molecu...
LCC TENDOlBhdGhvbG9neQ~~Idioma eng
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Construction and evaluation of a bladder cancer prognosis model based on super-enhancer-associated genes
Artículo
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Construction and evaluation of a bladder cancer prognosis model based on super-enhancer-associated genes
Lieyu Xu et al · Springer · 2026 · ISSN 2730-6011
Abstract Introduction Bladder cancer (BLCA) is a malignant tumour that occurs on the mucosa of the bladder. It accounts for the first place in the incidence of genitourinary tumours in China. BLCA is characterized by hig...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Does lateralization and distalization affect revision rates and patient experience in primary stemmed reverse total shoulder arthroplasty?
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Does lateralization and distalization affect revision rates and patient experience in primary stemmed reverse total shoulder arthroplasty?
David R.J. Gill, MB ChB, FRACS, FAOrthA et al · Elsevier · 2026 · ISSN 2666-6383
Background: This study examined the association between distalization and lateralization of implant components and revision outcomes and patient-reported outcome measures (PROMs) following primary total stemmed reverse s...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~; LCC:Diseases of the musculoskeletal systemIdioma eng
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Efficacy and safety analysis of CAR-T cell salvage therapy in relapsed/refractory diffuse large B-cell lymphoma after failure of bispecific antibody treatment
Artículo
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Efficacy and safety analysis of CAR-T cell salvage therapy in relapsed/refractory diffuse large B-cell lymphoma after failure of bispecific antibody treatment
Fuli Li et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) who failed bispecific antibody (BsAb) therapy face an extremely poor prognosis, necessitating exploration of effective salva...
LCC LCC:MedicineIdioma eng
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Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria among children 6–59 months in three sentinel sites of Sierra Leone, 2021–2022
Artículo
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Efficacy and safety of artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) for the treatment of uncomplicated Plasmodium falciparum malaria among children 6–59 months in three sentinel sites of Sierra Leone, 2021–2022
Irene Cavros et al · BMC · 2026 · ISSN 1475-2875
Abstract Antimalarial drug resistance leads to increased treatment failures, prolonged illness, and increased mortality. The World Health Organization (WHO) recommends malaria-endemic countries regularly (ideally biennia...
LCC TENDOkFyY3RpYyBtZWRpY2luZS4gVHJvcGljYWwgbWVkaWNpbmU~; TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Efficacy of cilastatin sodium in a translational large animal crush syndrome model
Artículo
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Efficacy of cilastatin sodium in a translational large animal crush syndrome model
Adam C. Munhall et al · Nature Portfolio · 2026 · ISSN 2730-664X
Abstract Background Crush syndrome (consisting of hyperkalemia, acidosis, hypocalcemia, and acute kidney injury), is the second-most common cause of death in earthquakes, and a frequent cause of critical illness after bu...
LCC LCC:MedicineIdioma eng
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Enrollment and patterns of participation in Swedish for immigrants (SFI): timing, duration, and selectivity
Artículo
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Enrollment and patterns of participation in Swedish for immigrants (SFI): timing, duration, and selectivity
Samaneh Khaef · SpringerOpen · 2026 · ISSN 2035-5556
Abstract In Sweden, as in most Western countries, language proficiency is widely recognized as a key component of immigrant integration, supported by initiatives such as the publicly funded language program known as Swed...
LCC TENDOkRlbW9ncmFwaHkuIFBvcHVsYXRpb24uIFZpdGFsIGV2ZW50cw~~Idioma eng
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Estimation of small dense low-density lipoprotein cholesterol and cardiometabolic multimorbidity risk in middle-aged and elderly Chinese: findings from a nationwide prospective cohort
Artículo
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Estimation of small dense low-density lipoprotein cholesterol and cardiometabolic multimorbidity risk in middle-aged and elderly Chinese: findings from a nationwide prospective cohort
Yifan Zhao et al · BMC · 2026 · ISSN 1471-2261
Abstract Background Cardiometabolic multimorbidity (CMM) poses a growing burden on aging populations. Small dense low-density lipoprotein cholesterol (sdLDL-C) is a key atherogenic particle, practically estimated by the ...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Exenteração pélvica para câncer do colo uterino recidivado pós-radioterapia: experiência de um centro terciário do Nordeste brasileiro Post-radiotherapy pelvic exenteration in relapsed cervical cancer: experience of a tertiary health service in the northeast of Brazil
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Exenteração pélvica para câncer do colo uterino recidivado pós-radioterapia: experiência de um centro terciário do Nordeste brasileiro Post-radiotherapy pelvic exenteration in relapsed cervical cancer: experience of a tertiary health service in the northeast of Brazil
Sabas Carlos Vieira et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2009 · ISSN 0100-7203
OBJETIVO: analisar complicações, morbidade, mortalidade e sobrevida num grupo de pacientes com câncer de colo uterino com recidiva pélvica central submetidas à exenteração pélvica pós-tratamento primário com ra...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Expressional and prognostic value of cytokine receptor-like factor 3 in liver hepatocellular carcinoma patients via integrated bioinformatics analyses and experiments
Artículo
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Expressional and prognostic value of cytokine receptor-like factor 3 in liver hepatocellular carcinoma patients via integrated bioinformatics analyses and experiments
Xingxing Wang et al · SAGE Publishing · 2026 · ISSN 2050-3121
Background: Liver hepatocellular carcinoma is a highly prevalent and lethal malignancy. The orphan cytokine receptor-like factor 3, although evolutionarily conserved and implicated in hematopoiesis and neuroprotection, r...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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First registry of adult patients with chronic intestinal failure due to short bowel syndrome in Argentina: The RESTORE project
Artículo
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First registry of adult patients with chronic intestinal failure due to short bowel syndrome in Argentina: The RESTORE project
Gondolesi, Gabriel Eduardo et al · Wiley · 2022 · ISSN 1623-1631
Background: Short bowel syndrome (SBS) is considered a low prevalence disease. In Argentina, no registries are available on chronic intestinal failure (CIF) and SBS. This project was designed as the first national regist...
Idioma eng
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Identification and validation of Kif15 as a potential diagnostic and prognostic biomarker in colon cancer
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Identification and validation of Kif15 as a potential diagnostic and prognostic biomarker in colon cancer
Huiming Wu et al · BMC · 2026 · ISSN 1471-230X
Abstract Objective This study aimed to systematically identify and validate KIF15 as a potential diagnostic and prognostic biomarker in colon cancer (CC) using integrated bioinformatics analyses. We further explored its ...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Identification of TRPM4 related genes in LUAD by RNA seq and spatial transcriptomics
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Identification of TRPM4 related genes in LUAD by RNA seq and spatial transcriptomics
Wei-jie Yu et al · Springer · 2026 · ISSN 2730-6011
Abstract Background Sodium overload-induced cell death is a novel mode of cell death that differs from other modes and is a very promising new target for cancer therapy. In addition, sodium overload-induced cell death pl...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Idiopathic nodular glomerulosclerosis and diabetic nephropathy: a histological and prognostic comparison highlighting the impact of smoking
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Idiopathic nodular glomerulosclerosis and diabetic nephropathy: a histological and prognostic comparison highlighting the impact of smoking
Kyara Baert et al · BMC · 2026 · ISSN 1471-2369
Abstract Introduction Idiopathic nodular glomerulosclerosis (ING) and diabetic nephropathy (DN) display (almost) identical kidney biopsy findings. Our aim was to investigate potential disparities in histology and clinica...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBnZW5pdG91cmluYXJ5IHN5c3RlbS4gVXJvbG9neQ~~Idioma eng
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Impact of good glycemic control on survival of pancreatic ductal adenocarcinoma with diabetes mellitus
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Impact of good glycemic control on survival of pancreatic ductal adenocarcinoma with diabetes mellitus
Hyun Joo Lee et al · BMC · 2026 · ISSN 1471-230X
Abstract Background While diabetes mellitus (DM) has been reported as a risk factor for development and prognosis of pancreatic ductal adenocarcinoma (PDAC), the specific impact of glycemic control on clinical outcomes r...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Impact of hypothyroidism on short-term and long-term outcomes in total hip arthroplasty: A national database propensity matched cohort study
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Impact of hypothyroidism on short-term and long-term outcomes in total hip arthroplasty: A national database propensity matched cohort study
Abdul-Lateef Shafau et al · Elsevier · 2026 · ISSN 2773-157X
Background: Hypothyroidism is a common endocrine disorder that presents challenges for total hip arthroplasty (THA) due to its effects on cardiovascular, metabolic, and immune systems. Prior studies associate hypothyroid...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~Idioma eng
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Implant survival and factors associated with failure of cemented custom-made distal femoral megaprostheses after tumor resection
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Implant survival and factors associated with failure of cemented custom-made distal femoral megaprostheses after tumor resection
Apostolopoulos Vasileios et al · EDP Sciences · 2026 · ISSN 2426-8887
Background: Distal femoral megaprosthetic reconstruction is a standard limb-salvage procedure after tumor resection. This study aimed to evaluate implant survival and associated factors, the incidence of mechanical failu...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~Idioma eng
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Improving lung cancer surgery outcomes in low-resource countries: the role of video-assisted thoracoscopic surgery
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Improving lung cancer surgery outcomes in low-resource countries: the role of video-assisted thoracoscopic surgery
Shero Ali Rasul et al · SpringerOpen · 2026 · ISSN 2662-2203
Abstract Background Lung cancer surgery in low- and middle-income countries (LMICs) is frequently challenged by late-stage presentation, high comorbidity burden, and limited healthcare resources. Although video-assisted ...
LCC TENDOlN1cmdlcnk~; TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Incidence and risk factors for incisional hernia after partial liver resection via an inverted L-incision: a retrospective single-centre cohort study
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Incidence and risk factors for incisional hernia after partial liver resection via an inverted L-incision: a retrospective single-centre cohort study
Banseok Kim et al · BMC · 2026 · ISSN 1471-2482
Abstract Background Incisional hernias are a relevant complication after abdominal surgery, but data on their occurrence after open liver resection, particularly via inverted L-incision, are limited. Methods We conducted...
LCC TENDOlN1cmdlcnk~Idioma eng
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Incidence, survival, and risk factors for first-line antiretroviral therapy failure among adults on ART follow-up in health facilities in Southwest Shoa, Oromia, Ethiopia, 2023: a retrospective cohort study
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Incidence, survival, and risk factors for first-line antiretroviral therapy failure among adults on ART follow-up in health facilities in Southwest Shoa, Oromia, Ethiopia, 2023: a retrospective cohort study
Setegn Gemechu et al · BMC · 2026 · ISSN 1471-2334
Abstract Background The inability of antiretroviral medications to inhibit HIV is known as antiretroviral treatment failure. One of the greatest problems facing HIV patients receiving antiretroviral therapy is treatment ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Integrating machine learning and clinicopathological data to stratify survival risk in young women with localized breast cancer
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Integrating machine learning and clinicopathological data to stratify survival risk in young women with localized breast cancer
Bin Xu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundYoung women with localized breast cancer represent a clinically distinct population with heterogeneous outcomes, yet age-specific prognostic models remain limited. Conventional risk stratification tools derived...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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