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74 resultados encontrados.

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The Feasibility and Preliminary Effects of a Stress Process Model-Based Program in Dementia Caregiving (DeCare-SPM) for Family Caregivers: A Mixed-Methods Pilot Study
Artículo
Material complementario disponible Artículo DOAJ
Wu J et al · Dove Medical Press · 2026 · ISSN 1178-2390
Jie Wu,1,* Xuelian Li,1,* Weichu Liu,2 Yingzhuo Ma,1 Qinghua Zhao,1 Mingzhao Xiao,1 Jun Wang1 1Department of Nursing, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s R...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Material complementario
Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium
Artículo
Acceso abierto Artículo CONICET Digital
Sexton, Claire et al · Wiley Blackwell Publishing, Inc · 2022 · ISSN 1957-1968
As research and services in the Mediterranean region continue to increase, so do opportunities for global collaboration. To support such collaborations, the Alzheimer's Association was due to hold its seventh Alzheimer's...
Idioma eng
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Open Access
An eye-tracking-based Stroop test: an efficient method for evaluating frontal lobe function
Artículo
Acceso abierto Artículo DOAJ
Sho Yamamoto et al · Frontiers Media S.A · 2026 · ISSN 1663-4365
IntroductionAssessing attention and frontal lobe function is essential for diagnosing dementia. The Stroop test is widely used for these purposes, and its validity and reliability have been verified. Nevertheless, test-r...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice
Artículo
Acceso abierto Artículo CONICET Digital
Alfieri, Julio Armando et al · Frontiers Research Foundation · 2016 · ISSN 1663-4365
Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43). To investigate in depth the b...
Idioma eng
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Neurological manifestations in people with HIV in HAART era: a cross-sectional multicenter study
Artículo
Acceso abierto Artículo DOAJ
Lu Lu et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
BackgroundThe landscape of neurological manifestations of HIV remains unknown after HAART is applied. This study aimed to characterize the spectrum of neurological disorders in people with HIV.MethodsThis cross-sectional...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Periodontal status in patients with Alzheimer’s disease: a scoping review
Artículo
Acceso institucional disponible Artículo DOAJ
Kartika Indah Sari et al · faculty of dentistry universitas gadjah mada · 2022 · ISSN 2460-0164
Periodontitis is the most common condition of chronic periodontal infection and inflammation in the elderly population. Periodontal disease can cause local inflammation that contributes to higher risk of systemic inflamm...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Peripheral Blood Regulatory T Cells and IL-6 are Associated with Cognitive Impairment After Acute Ischemic Stroke
Artículo
Acceso abierto Artículo DOAJ
Chang Y et al · Dove Medical Press · 2026 · ISSN 1178-2021
Yueyue Chang,1,2 Xuke Zhang,3 Chuanqing Yu,2 Lei Zhu,1 Shiyu Sun,2 Zhongwu Sun1 1Department of Neurology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People’s Republic of China; 2Department of ...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng
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Protocol for a Pre‐Post Field Trial of a Home Hearing and Vision Care Program for Older Australians With Diverse Cognitive Abilities and Hearing and/or Vision Impairment
Artículo
Acceso abierto Artículo DOAJ
Melinda Toomey et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Hearing and vision impairments are prevalent health conditions among older adults, negatively affecting functional ability, mental and social well‐being, quality of life and increasing the ...
LCC LCC:MedicineIdioma eng
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Open Access
SOCAV, a nurse-led program promoting self-direction in nursing homes: a longitudinal mixed-methods pilot study
Artículo
Acceso abierto Artículo DOAJ
Phébe Das et al · BMC · 2026 · ISSN 1471-2318
Abstract Background This study evaluates the impact of the SOCAV program on promoting self-direction of individuals with dementia in nursing homes and examines the behavioral changes in care staff when trained and coache...
LCC TENDOkdlcmlhdHJpY3M~Idioma eng
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Ciliary p75 neurotrophin receptor (p75NTR) facilitates the enrichment of exogenous amyloid beta (Aβ 1–42) peptide and promotes oxidative stress in human hippocampal astrocytes
Artículo
Acceso abierto Artículo DOAJ
Ankan Gupta et al · BMC · 2026 · ISSN 2661-8850
Abstract Accumulation of amyloid beta 1–42 (Aβ42) peptide in the extracellular space in the brain is a major observation in Alzheimer’s Disease (AD)-related pathology. Astrocytes are known to play pivotal role in cl...
LCC LCC:CytologyIdioma eng
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Open Access
Health and burnout of home health care assistants: Impact of a training intervention
Artículo
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Javier Saavedra et al · Servicio de Publicaciones de la Universidad de Murcia · ISSN 0212-9728
Abstract: There is a growing need for care in developed countries, so the number of home health care assistants has increased exponentially. The literature has pointed out that this professional group is at high risk for...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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The epidemiology of neurocognitive disorders in Hungary
Artículo
Acceso abierto Artículo DOAJ
Christopher Váraljai et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract There is a lack of data on the epidemiological characteristics of NCD (neurocognitive. disorder) in Hungary. We aimed to assess the prevalence and incidence of NCD in Hungary, by sex and age groups, and to deter...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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A biological classification for Alzheimer's disease - Amyloid, Tau and Neurodegeneration (A/T/N): Results from the Argentine-Alzheimer's Disease Neuroimaging Initiative
Artículo
Acceso abierto Artículo CONICET Digital
Allegri, Ricardo Francisco et al · Cambridge University Press · 2018 · ISSN 1041-6102
Objective: To describe the Amyloid, Tau, Neurodegeneration (A/T/N) research framework classification in the Argentine-Alzheimer Neuroimaging Initiative (ADNI) cohort. Methods: 23 Mild Cognitive Impairment (MCI), 12 Alzhe...
Idioma eng
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Open Access
A mini review: The role of dietary supplements in improving health outcomes of chronic diseases in elderly patients
Artículo
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Maryam Farrukh et al · AMMANIF · 2025 · ISSN 2521-0521
The goal of the medical specialty of geriatrics is to treat the complicated needs of elderly patients while highlighting the need of preserving functional independence in the face of chronic illnesses. A unique and compr...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Accuracy of the 15-item Geriatric Depression Scale (GDS-15) in a community-dwelling oldest-old sample: the Pietà Study
Artículo
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Filipi Leles da Costa Dias et al · Associação de Psiquiatria do Rio Grande do Sul · ISSN 2238-0019
Abstract Introduction Late-life depression (LLD) is common, but remains underdiagnosed. Validated screening tools for use with the oldest-old in clinical practice are still lacking, particularly in developing countries....
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Open Access
Acetylcholinesterase inhibitory activity of a naturally occurring peptide isolated from Boana pulchella (Anura: Hylidae) and its analogs
Artículo
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Sanchis, Ivan et al · Springer · 2020 · ISSN 0939-4451
Alzheimer’s disease (AD), the most common form of dementia, is a growing problem worldwide, with 10 million incident cases registered every year. The complex etiology of AD has not been clarified yet and represents an ...
Idioma eng
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Anti-Aβ3–10 monoclonal antibody 7B8 improves cognitive function and protects the blood-brain barrier in APP/PS1 mice by regulating the HMGB-1/RAGE/NF-κB pathway
Artículo
Acceso abierto Artículo DOAJ
Jiayu You et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
BackgroundAlzheimer’s disease (AD), the most prevalent dementia, is primarily underpinned by the amyloid cascade hypothesis. Passive Aβ immunotherapy effectively reduces cerebral Aβ deposition but is limited by sever...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Association Between Age-Related Sensory and Metabolic Hearing Loss and Cognitive Performance
Artículo
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Mie L. Jørgensen et al · SAGE Publishing · 2026 · ISSN 2331-2165
The underlying mechanisms linking age-related hearing loss (HL), and cognitive dysfunction are not well-understood. Traditionally, age-related HL was primarily related to damage of hair cells (i.e., the sensory component...
LCC TENDOk90b3JoaW5vbGFyeW5nb2xvZ3k~Idioma eng
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Association between neurofilament light chain, glial fibrillary acidic protein, and sarcopenia in older Indian adults: evidence from LASI-DAD
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Abhijith Rajaram Rao et al · BMC · 2026 · ISSN 1471-2318
Abstract Background Sarcopenia, the age-related loss of muscle mass and strength, is a leading cause of disability and frailty in older adults. Though primarily seen as a musculoskeletal condition, emerging evidence sugg...
LCC TENDOkdlcmlhdHJpY3M~Idioma eng
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Case Report: Massive rectal bleeding from stercoral ulcers in a pediatric patient
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Paolo Quitadamo et al · Frontiers Media S.A · 2026 · ISSN 2813-1169
A 10-year-old patient was admitted to the pediatric sub-intensive care unit due to massive rectal bleeding and severe acute anemia. His medical background included Asperger syndrome and a history of chronic constipation ...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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Cognitive decline in older persons initiating anticholinergic medications.
Artículo
Material complementario disponible Artículo DOAJ
Raj C Shah et al · Public Library of Science (PLoS) · 2013 · ISSN 1932-6203
BackgroundThis study examines the effect of initiating medications with anticholinergic activity on the cognitive functions of older persons.MethodsParticipants were 896 older community-dwelling, Catholic clergy without ...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Determinants of mortality following intertrochanteric fractures, comorbidities versus reduction quality: retrospective cohort study
Artículo
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Bugra Kundakci et al · BMC · 2026 · ISSN 1749-799X
Abstract Background Intertrochanteric femoral fractures are common in the elderly population and are associated with substantial mortality. While fracture reduction quality is known to influence mechanical outcomes, its ...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~; LCC:Diseases of the musculoskeletal systemIdioma eng
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Digital health interventions for older adults with subjective cognitive decline or mild cognitive impairment: a systematic review and meta-analysis of randomized controlled trials
Artículo
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Nan Xu et al · BMC · 2026 · ISSN 1471-2318
Abstract Background Subjective cognitive decline and mild cognitive impairment represent critical windows for intervention as early stages of dementia progression. Although digital health interventions have shown potenti...
LCC TENDOkdlcmlhdHJpY3M~Idioma eng
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Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes
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Bachor, Tomás Pedro et al · Academic Press Inc Elsevier Science · 2017 · ISSN 0969-9961
Diabetes mellitus (DM) is reaching epidemic conditions worldwide and increases the risk for cognition impairment and dementia. Here, we postulated that progenitors in adult neurogenic niches might be particularly vulnera...
Idioma eng
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