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ABSTRACT Background and Aims De novo drug design is the process of generating novel lead compounds that possess desirable pharmacological activities and optimal physicochemical properties for therapeutic development. In ...

Abstract Modern antenna design is an intrinsic undertaking. It relies heavily on expert knowledge and computational tools, especially electromagnetic (EM) simulation software. The most daunting phase is the development o...

In the current environment there is a growing need for rapid development of advanced manufacturing technologies. The complexity of such projects requires the integration of work from various technical specialties. If t...

IntroductionEducation for sustainable development (ESD) has become a key focus in higher education transformation. Design disciplines play a unique role in cultivating students' creativity to address complex social and e...

Over 70% of pharmaceutical compounds face the challenge of poor water solubility, which impacts on their bioavailability. This study focuses on the use of Santa Barbara Amorphous-15 (SBA-15) mesoporous silica material as...

Mobile Edge Computing (MEC) brings computation close to end-users to support latency-sensitive applications, such as tele-manipulation and autonomous driving. While Network Function Virtualization (NFV) facilitates the d...

IntroductionThe deserts of Saudi Arabia are rich in rock art and cultural heritage sites, with ancient murals in the AlUla region holding significant symbolic meaning. Heritage plays an important role in preserving cultu...

Abstract Background A high prevalence of child overweight and obesity worldwide calls for innovative multi-setting intervention approaches, and thorough evaluation. This paper describes the protocol for the process evalu...

Office buildings have frequently changed from the past to the present due to historical factors (the collapse of empires, colonialism and expansionist policies, the industrial revolution, wars, the development of technol...

Abstract The identification of pork in commercially processed meats is one of the most crucial issues in the food industry because of religious food ethics, medical purposes, and intentional adulteration to decrease prod...

Plasmonic nanoantennas with suitable far-field characteristics are of huge interest for utilization in optical wireless links, inter-/intrachip communications, LiDARs, and photonic integrated circuits due to their except...

The growing presence of generative artificial intelligence (GenAI) in educational practice raises questions about how learners and educators live with AI and reshapes questions about how learning unfolds across contempor...

Background and objectivesMitochondrial dysfunction and oxidative stress are key contributors to the progression of Alzheimer’s disease (AD). Salidroside, a bioactive glycoside derived from Rhodiola rosea, exhibits neur...

Processing residues from adult Tenebrio molitor were evaluated as a sustainable source of chitin and chitosan through an optimized enzyme-assisted extraction strategy. Preliminary proximate analysis revealed a high chiti...

This article explores the idea of living in outdoor environmental design. It works to highlight the necessity of creating outdoor spaces that will simultaneously create positive physical and mental health effects while o...

This study utilizes the DALL-E artificial-intelligence (AI) model to generate both traditional and modern architectural visuals that follow the Kıyıköy Conservation Master Plan for the historic coastal town of Kıyık...

The amount of climate-active substances emissions depends on the technology and the mode of manure processing. Current methodologies for calculating these emissions are based on aggregated coefficients that do not consid...

The characteristics and duration of the processes occurring from the design and designation of a Marine Protected Area (MPA) to the effective implementation and renewal of its management plan were analysed in 234 MPAs fr...

"Decision support systems for alert drug-drug interactions have been shown as valid strategy to reduce medical error. Even so the use of these systems has not been as expected, probably due to the lack of a suitable desi...

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

This paper proposes an innovative automated multiphysics Microelectromechanical systems (MEMS) co-optimization platform integrating the embedded reduced-order modeling offered by Coventor MEMS+ with MATLAB’s numerical ...

Abstract The liner of a CNG pressure vessel is manufactured by a DDI (deep drawing and ironing) process for the cylinder part, which is a continuous process that includes a drawing process to reduce the diameter of the b...

It can be said that today's civil aviation basics began to be laid in the 1950s. This date is also important as the period in which the rules are being written and at the same time, some system solutions are produced by ...

To ensure the perennity of natural resources, the valorisation process of herbal pharmaceuticals must be assessed for sustainability from the very beginning of its design. No specific tools have been developed for this p...