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Cryptosporidiosis is a zoonotic protozoan disease that affects humans and animals. This disease, which causes diarrhea, dehydration, weight loss, stunted growth, and death, especially in newborn calves, leads to economic...

Circulating cell-free DNA (cfDNA) is valuable for molecular testing, but typically requires specialized collection tubes or immediate processing. We investigated whether residual plasma from heparin separators, routinely...

Abstract Background Genetic analysis of the mitochondrial genome (mitogenome) has become essential for breed characterization, population genetics, and taxonomic studies in livestock. Genetic variations in mitochondrial ...

Background: Panicoideae are the second largest subfamily in Poaceae (grass family), with 212 genera and approximately 3316 species. Previous studies have begun to reveal relationships within the subfamily, but largely la...

Abstract We present HiChew, a novel chromatin conformation capture method combining efficient sticky-end ligation with post-PCR methylation-based enrichment. HiChew achieves approximately 50% valid pair ratios compared t...

ABSTRACT Onion is predominantly grown under conventional management. Alternatively, the no-tillage vegetable system uses cover crops to form a residue layer, which improves soil physical, chemical, and biological quality...

Abstract Background/Objectives Dilated cardiomyopathy (DCM) is characterized by heart failure and cardiac dilation, distinguishing it from ischemic and non-ischemic heart diseases. To date, more than 50 genes have been i...

Abstract Background CS2164 is an oral multi-target inhibitor that targets angiogenesis-related kinases, mitosis-related kinases, and chronic inflammation-related kinases. However, the added clinical benefit of CS2164 com...

ABSTRACT Background The genome‐wide profiling of chromatin states that are defined by different histone posttranslational modifications, known as epigenomic profiling, is crucial for understanding the epigenetic regula...

BackgroundGranular cell astrocytoma (GCA) is a rare, morphologically distinct variant of IDH-wildtype glioblastoma that can appear deceptively low-grade yet behave aggressively. Its molecular features remain poorly defin...

ObjectiveTo analyze the microbial community structure， distribution of antibiotic resistance genes and virulence factors in Flammulina velutipes using metagenomic sequencing， and explore its potential food safety ris...

Genetics, the study of heredity and genetic variation, is vital to biology education. Genome sequencing (GS), which decodes an organism’s entire DNA, represents a major advance in the field yet remains difficult for st...

Abstract Whole-genome sequencing (WGS) of morphology-selected sperm pools provides an exploratory approach for investigating genomic features associated with variable sperm quality. In this study, pooled DNA from 1500 in...

PurposePreimplantation genetic testing for aneuploidy (PGT-A) is essential for selecting embryos free from chromosomal abnormalities before transfer. However, challenges such as detection failures, mosaicism, and the lim...

ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify ...

Abstract Background Circulating cell-free DNA (cfDNA) is a promising biomarker for non-invasive early cancer detection. We integrated methylation entropy, a measure of DNA methylation heterogeneity, with other cfDNA feat...

Abstract Background Human patients with Ehlers‐Danlos syndrome (EDS) are categorized into subtypes based on causative genetic variants and phenotypes. The classical form of EDS, primarily caused by variants in COL5A1 o...

Transposable elements (TEs) make up almost half of the human genome and are among its most densely methylated regions. Their epigenetic silencing is crucial for genomic stability and immune homeostasis, and accumulating ...

In this study Streptomyces were isolated from 50 bacterial isolates taken from 30 soil samples, these samples were collected from various locations in Iraq's various regions.  The species of Streptomyces were isolated u...

Insertion/deletion (indel) polymorphisms in the bovine PRNP gene promoter region (23 bp) and intron 1 (12 bp) influence gene expression and susceptibility to bovine spongiform encephalopathy (BSE). Conventional detection...

ABSTRACT The objective of the present study was to investigate the effect of single nucleotide polymorphism (SNP) of the melanocortin 1 receptor (MC1R) gene on plumage coloration in mule ducks. PCR-high-resolution meltin...

X-linked agammaglobulinemia (XLA) is an inherited inborn error of immunity caused by low or absent Bruton tyrosine kinase activity, resulting in impaired B cell development, poor immunoglobulin production, and severe, re...

Abstract Hemotropic mycoplasmas in dogs, such as Mycoplasma haemocanis, have been described worldwide. Recently, these pathogens have been reported to be causative agent of zoonosis. It is known that its transmission may...

Background: Retinoblastoma is a hereditary cancer of childhood caused by mutations in the RB1 tumor suppressor gene. An early diagnosis is critical for survival and eye preservation, thus identification of RB1 mutations ...