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BackgroundImmune checkpoint inhibitors (ICIs) have markedly improved outcomes in metastatic microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) gastrointestinal (GI) malignancies. However, in frag...

Abstract Objective To identify maternal factors associated with the presence of low birth weight in term neonates. Methods Matched hospital-based case-controlled study performed in a high complexity institution locat...

Abstract Introduction There have been increasing concerns about the possible high prevalence of chronic kidney disease (CKD) among returnee Nepalese migrant workers from the Gulf countries and Malaysia. This population-b...

ABSTRACT Background and Aim Undernutrition is gradually declining worldwide except in sub‐Saharan Africa and parts of South Asia. Prevalence is almost stagnant in low‐and middle‐income countries (LIMCs), contributi...

Abstract Objective There are few multinational studies on gestational trophoblastic neoplasia (GTN) treatment outcomes in South America. The purpose of this study was to assess the clinical presentation, treatment outco...

The purpose of this paper is to investigate determinants of foreign direct investments (FDI) in the Visegrad Group countries. The theory indicates that FDI are mainly driven by market and efficiency seeking motives. Fore...

Abstract Background High‐income countries offer social assistance (welfare) programs to help alleviate poverty for people with little or no income. These programs have become increasingly conditional and stringent in r...

Background and Objectives: Climate change, resulting from the continuous increase in greenhouse gas emissions, has become one of the most critical global challenges. The IPCC’s Sixth Assessment Report emphasizes that l...

ABSTRACT Background Managing biomedical waste (BMW) effectively is a pressing public health challenge, particularly in low‐resource settings in accordance with the World Bank classification of low‐ and middle‐incom...

The paper empirically examines and assess the relationship between public debt and economic growth in the European transition countries from 1995 to 2017 (both years inclusive). The study attempts to identify and deter...

BACKGROUND AND OBJECTIVES: Urban areas are major sources of carbon emissions, and rapid urban growth in developing countries poses sustainability challenges. Qazvin, a medium-sized industrial city in Iran, faces rising e...

Background Low-value care (LVC) research originates predominantly from Western healthcare systems. This narrative review offers the first synthesis of LVC patterns, determinants and reduction initiatives across six diver...

This study investigates the health impacts of transitioning from Gavi, the Vaccine Alliance, on vaccination coverage, infant and under-5 mortality, and disability-adjusted life years (DALYs) in low and middle-income coun...

ABSTRACT Background and Aims Preeclampsia remains a leading cause of maternal and perinatal morbidity and mortality globally, with high incidence and case fatality rates in low‐ and middle‐income countries (LMICs). E...

Abstract Although information on minor blood group antigen frequencies is limited in many low- and middle-income countries, extended red blood cell (RBC) phenotyping is crucial for reducing alloimmunization in patients u...

There are always a few economic policy targets to be achieved at a given time. Politicians always strive to simultaneously achieve the optimal size for each of them. However, these targets are always at least partly cont...

Introduction Tuberculosis (TB) remains a significant health burden in 25 low- and middle-income countries. Despite TB being more cost-effective to prevent and treat its funding is disproportionately lower than that of HI...

Background: As populations age and hypertension prevalence rises, the burden of hypertension-attributable chronic kidney disease (CKD) keeps aggregating and varies across regions. A systematic assessment of how disease b...

Abstract Background Epidermolysis bullosa (EB) is a rare genetic disorder that causes extreme skin fragility, chronic pain, and functional impairment, with major psychosocial and economic consequences. Health-related qua...

Abstract Background Malnutrition is a key global health challenge and a major contributor to childhood morbidity and mortality. In recent times, the contrasting coexistence of undernutrition including micronutrient defic...

This Campbell systematic review examines the empirical research on the effectiveness of female genital mutilation/cutting (‘FGM/C’) interventions to reduce the occurrence of FGM/C practices in the 28 African countrie...

This article aims to create country profiles for European Union Member States, based on indicators that capture digital access and usage, business digitalisation and e-commerce, as well as human capital and innovation ca...

Against the global backdrop of accelerating climate change and the urgent need for energy transition, understanding the role of protected areas in shaping renewable energy consumption has become increasingly important. U...

The cervical cancer screening programs (CCSP) have not beenvery efficient in the developing countries. This explains the needto foster changes on policies, standards, quality control mechanisms,evaluation and integration...