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Objectives To characterise post-stroke depression (PSD) diagnostic and treatment patterns in an outpatient primary care setting, including timing, screening methods, therapeutic interventions and associations with mortal...

BackgroundDepressive disorders are clinically heterogeneous and mechanistically complex psychiatric conditions. Transcranial direct current stimulation (tDCS), a key non-invasive neuromodulation technique, has expanded r...

Background One potential modifiable factor to improve the mental health of healthcare professionals (HCPs) during the pandemic is lifestyle.Aims This study aimed to assess whether an improved lifestyle during the pandemi...

Abstract Objective: To report a case of post-electroconvulsive therapy spontaneous seizures in a patient medicated with sertraline, bupropion and risperidone. Case description: A 53-year-old woman with recurrent majo...

BackgroundChronic low back pain (CLBP), with or without radicular pain (RP), is a major cause of disability and reduced quality of life. Psychological comorbidities such as depression, anxiety, and chronic pain disorder ...

Abstract Background Hypertension affects a significant number of people globally, with the majority in low- and middle-income countries. Psychological distress such as anxiety, depression and stress, may occur as a conse...

Background: Medication non-adherence, potentially influenced by psychological and social factors, is a major barrier to effective treatment of tuberculosis. This study aimed to examine the associations between anxiety, d...

We propose that the excitability margin (ΔVmargin), defined as the difference between spike threshold and resting membrane potential, may function as a quantitative gating variable linking chronic stress, inflammatory l...

Abstract Introduction: The world renowned comedian and four-time Oscar nominated actor Robin Williams died on August 11, 2014. From the outset, the news indicated that his death was believed to be a suicide and this was...

IntroductionThis study examined the impact of the Collaborative Care Model (CoCM) on patients' subjective perceptions of clinician communication, treatment timeliness, and overall treatment quality, with a particular foc...

A comprehensive structural, petrological, and geophysical study of the 385 ± 2 Ma Devonian El Hornito Pluton (EHP) in the Sierra Grande de San Luis, Argentina, is presented. We establish that the EHP results from the in...

Abstract Objective Eating disorders (ED) are most prevalent in women of reproductive age. EDs affect fertility, maternal BMI, and obstetric outcomes. During the early postpartum period, women with an ED history are at hi...

Background The Anxiety Symptoms Questionnaire (ASQ) is a brief self-report questionnaire which measures frequency and intensity of symptoms and was developed to improve assessment of anxiety symptoms in a clinical settin...

Mental health issues, including cognitive impairment, anxiety, and depression, have become a major global health challenge. Notably, conventional pharmacological treatments are often accompanied by adverse reactions. The...

BackgroundAdolescent depression is a major public health concern, yet the relative contributions of smartphone use duration and perceived loneliness remain unclear. This study examined their independent and comparative a...

Chronic psychosocial stress is a major risk factor for anxiety, depression and related disorders, yet a hypothalamic-pituitary-adrenal (HPA) axis centric framework alone is insufficient to explain stress-induced vulnerab...

Introduction: Suicide is a major public health problem, in which relatives play an important role in the prevention of the said problem. However, suicide and suicidal behavior affect the relatives’ lives profoundly, bo...

Background: Caregivers are individuals responsible for assisting older, sick, or disabled persons. The majority of care services are provided by family members acting as primary caregivers. Providing care for older peopl...

We assessed the effect of xylem sap flux on radial CO2 efflux of woody tissue of a tropical trees species growing in the Center of Manaus (Amazonas State, Brazil). An open chamber system was used to constantly measure di...

Abstract BackgroundEveryday digital technologies such as social media, gaming, and internet use are deeply integrated into the lives of children, adolescents, and young adults. While these platforms can foste...

RationaleCommon variable immunodeficiency (CVID) is a chronic, multisystem immune disorder associated with substantial symptom burden beyond infections, particularly among individuals with noninfectious inflammatory comp...

In patients with end-stage renal disease (ESRD), depression is the most commonly identifi ed psychiatric illness; however, its prevalence varies since it is assessed by using different methods in different studies and in...

"The COVID-19 pandemic has caused major disruptions in people’s lives around the globe. Sleep habits and emotional balance have been disturbed in a way that could be comparable to the havoc caused by a deep personal cr...

Abstract Introduction The geriatric population is the fastest-growing age group and accounts for one-third of surgical patients. A growing body of evidence reveals that postoperative cognitive dysfunction (POCD) is the m...