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Behcet's disease (BD) is a systemic chronic vasculitis of unknown aetiology characterised by mainly oro-genital ulcers. Renal involvement in BD is seen much less frequently than one would expect in a systemic vasculitis....

Wegener's Granulomatosis (WG) is characterized by necrotizing granulomatous lesions of the respiratory tract, glomerulonephritis and frequently vasculitis involving other organs. We reported the different features of WG ...

Abstract Background Kawasaki disease (KD) is an acute systemic vasculitis of childhood and the leading cause of acquired heart disease in children in developed countries. Infants frequently present with incomplete diseas...

BackgroundGATA2 deficiency results from heterozygous pathogenic variants in the GATA2 gene, which encodes a zinc-finger transcription factor essential for hematopoietic stem and progenitor cell development. It is a highl...

OBJETIVO: Avaliar a influência das complicações maternas, da prematuridade, dos parâmetros antropométricos do feto e de condições do recém-nascido nos diferentes graus de corioamnionite. MÉTODOS: Foram analisada...

Abstract Background Equine herpesvirus myeloencephalopathy (EHM) has severe impact on the sport horse population. Objective Study the influence of EHM on the likelihood of affected horses to return to their previous perf...

The complement system is a mediator and marker of renal damage. There are three pathways of complement activation: classical, alternative and lectin pathway. Lectin pathway is initiated by binding of mannose-binding lect...

Metformin is the most widely used oral antidiabetic drug in the world. It is the first-line drug in type 2 diabetes, where its inhibiting effect on hepatic glucose production, increasing muscle and adipose tissue insulin...

Microscopic polyangiitis nodosa (MPA) is a necrotizing vasculitis that affects small vessels, typically associated with myeloperoxidase anti-neutrophil cytoplasmic antibody. Cerebrovascular diseases are rarely reported t...

Henoch-Schönlein purpura (HSP), characterized by non-thrombocytopenic purpura accompanied by arthritis/arthralgia, gastrointestinal and genitourinary system involvement is the most common vasculitis in childhood. Associ...

IntroductionPolyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis affecting medium-sized vessels. While peripheral neuropathy occurs in 50–75% of patients, cranial nerve involvement is exceptionally rare...

Polycythemia vera (PV) is a JAK2-mutated myeloproliferative neoplasm associated with thrombotic and vascular complications. Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that may involve the aorta...

Wegener’s granulomatosis (WG) is a disorder that causes necrotizing granulomatosis vasculitis particularly of the upper respiratory tract, lung and kidney. A 43-year-old male who had been treated with hemodialysis beca...

BackgroundBehçet’s disease is a multisystem inflammatory disorder whose diagnosis can be challenging due to overlapping features with other inflammatory conditions and primary immunodeficiencies (1). In patients with ...

Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis of childhood, but the etiology is not known. Familial occurrence of HSP is rare. There are only two previous reports of the simultaneous onset of HSP...

Takayasu arteritis is a vasculitis of aorta and large vessels and it is rarely diagnosed in childhood in Turkey. An 11-year old girl was admitted for the manifestations of hypertensive cardiomyopathy and congestive heart...

This study is performed in Istanbul University Cerrahpaşa Medical Faculty Haemodialysis Unit. 172 patients (mean age 45 years; 109 males, 63 females) regularly dialysed for at least longer than 3 months in our unit betw...

Wegener granulomatosis (WG) is a type of necrotising vasculitis that affects mainly the respiratory tract, paranasal sinuses and the kidneys. Urogenital involvement is rare; mainly affecting the prostate gland. Testicula...

OBJECTIVE: Recently, urinary angiotensinogen (AGT) is used frequently as a marker of intrarenal renin-angiotensin-aldosterone system (RAAS) activity. In this study, we aimed to investigate the relationship between urinar...

Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the sacroiliac joints, spine, and peripheral joints. The widespread application of biological agents has led to significant clinical im...

Plasma exchange (plasmapheresis) is a treatment method based on separating the plasma, one of the 4 components, from whole blood removed from the body and giving the remaining part back to the circulation with replacemen...

Encephalitis in immunocompromised individuals presents a unique diagnostic and treatment challenge due to the interplay between infection and immune dysregulation.A 48-year-old male with a history of recurrent sinusitis ...

Resumen La enfermedad de Behçet es una vasculitis multisistémica cuya etiopatogenia es aún desconocida. Las complicaciones arteriales que tienen una relación directa con la enfermedad en las formas pediátricas son m...

El eritema indurado de Bazin (EIB), afección de baja incidencia en nuestro medio, es una enfermedad nodular crónica, recurrente, asociada a una hipersensibilidad retardada a antígenos micobacterianos que típicamente ...