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ABSTRACT Developing countries face great challenges to couple agricultural intensification and sustainable supply chain development. This paper explores the opportunities for innovation in the conservation of the locally...

Abstract Background Deaths from suicide, drug overdose, and alcohol-specific causes, collectively termed “deaths of despair” (DoD), represent a growing public health concern. Quantitative research has linked these de...

Abstract Background Previous studies have indicated that chronic emotional stressors likely participate in the occurrence of cancers. However, direct evidence connecting stress and colorectal cancer development remains a...

Milk sector in Algeria presents lasting supply instability and its development policy has not achieved the expected results. The interest in developing local dairy production therefore has been a priority for public auth...

Abstract Dysregulated expression of tumor suppressor genes can impair their functions, even promoting oncogenesis. Expression of p53β mRNA can be regulated by alternative splicing and RNA surveillance, otherwise transla...

Abstract Since the first report in 1972, several studies have documented an association between Parkinson’s disease (PD) and melanoma. Up to 20-fold increased risk of melanoma was reported in PD patients, while a perso...

The safety of core wall type rockfill dams during reservoir impounding is greatly affected by the slaking deformation of upstream shell materials. The slaking deformation of the rockfill materials is analyzed using the t...

A novel closed-loop control methodology is introduced to stabilize a cylinder wake flow based on images of streaklines. Passive scalar tracers are injected upstream the cylinder and their concentration is monitored downs...

Abstract NH₃ and H₂S are major hazardous odorants emitted from intensive livestock operations, presenting distinct challenges for simultaneous removal. This study evaluates a novel layered filtration system utilizing...

Abstract DNA double-strand break (DSB) represents the most severe form of DNA damage, and both defective and hyperactive repair can compromise genome stability. It is known that blue light promotes DSB repair by cryptoch...

A growing number of therapies are being developed to target the cell cycle machinery for the treatment of cancer and other human diseases. Consequently, a greater understanding of the factors regulating cell cycle progre...

ABSTRACT Nitrate (NO3−) is a major nutrient promoting plant growth and crop yield. Vacuolar nitrate storage is essential for nitrate acquisition and remobilization within the plant. However, the transcriptional regulat...

As pressures on water and energy systems increase, integrated governance of water-energy nexus has gained importance. In Brazil, where hydropower is the main source of electricity and droughts are frequent, managing this...

BackgroundSeptic cardiomyopathy (SCM) is one of the most common and serious complications of sepsis. Earlier research has identified reciprocal regulation between SCM and gut microbiota (GM), but the mechanistic basis of...

Abstract Background Temperate phages play a central role in the evolution and pathogenicity of Staphylococcus aureus. Sa3int phages provide highly human-specific virulence factors that promote immune evasion and survival...

Vascular and metabolic diseases, including atherosclerosis, aortic aneurysm and dissection, obesity, type 2 diabetes, and metabolic dysfunction–associated steatotic liver disease (MASLD), constitute a major global heal...

Abstract DNA replication timing (RT) often correlates with transcription during cell fate transitions, yet notable exceptions indicate a complex relationship. Using a reductionist system in mouse embryonic stem cells, we...

In Salmonella enterica serovar Typhimurium, the RcsCDB regulatory system controls the expression of genes involved in synthesis of colanic acid, formation of flagella and virulence. Here, we show that activation of the R...

ABSTRACT The Hna phage defense system is one of many systems that protect bacteria against bacterial viruses (phages). Hna was first discovered in the nitrogen-fixing alphaproteobacterium Sinorhizobium meliloti, which fo...

Stalk-lodging and drought are major constraints limiting maize productivity. We previously characterized B73 as stalk-lodging resistant but drought-sensitive maize inbred, while EA2024 is stalk-lodging susceptible and dr...

Abstract Proper regulation of ribosome biogenesis is essential for stem cell function and tissue homeostasis, yet its upstream control in adult intestinal stem cells (ISCs) remains unclear. Here, we identify the WD repea...

La industria del petróleo y gas argentina atraviesa un punto de inflexión impulsado por el desarrollo de Vaca Muerta y la creciente incorporación de ciencia de datos como herramienta de transformación operativa y est...

"En un contexto en el que las empresas buscan mejorar su performance, la integración con sus socios aguas arriba y aguas abajo, se convierte en un elemento clave, en términos de costos, tiempos y flexibilidad. Las rela...

El barrenador de los brotes de la soja, Epinotia aporema (Lep. Tortricidae) es una importante plaga de leguminosas en América del sur. En Argentina, este insecto ocasiona reducciones en los rindes de soja de hasta el 40...