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The therapeutic benefit of phosphorothioate oligodeoxynucleotides (PS-ODN) containing immune stimulatory sequences has been demonstrated in animal models of cancer and infection. Several tools are available for the deter...

Background: This study developed and systematically optimized an ion-pair hydrophilic interaction liquid chromatography (IP-HILIC) system for oligonucleotide medicine analysis, aiming to the issues of insufficient resolu...

ObjectiveExtremely thick aquifers in mining areas typically exhibit strong heterogeneity and high water yield. Therefore, they are prone to cause severe water inflow in mines and induce water disasters, representing a ma...

Introduction According to modern scholars (N. Maslova, B. Astafiev), one of the important reasons for the global planetary crisis, including modern educational system in particular, is violation of the conformity of natu...

The article analyzes the theoretical foundations and practical aspects of implementing artificial intelligence (AI) technologies in educational and scientific space. Based on a systematic analysis of international resear...

The article is devoted to the analysis of international security within contemporary International Relations theory, with a particular focus on levels of analysis and explanatory frameworks. The relevance of the topic is...

Fungi are ubiquitous across nearly all habitats and play pivotal roles in maintaining ecological sustainability. Understanding the composition and functional roles of active fungal communities is essential for elucidatin...

Abstract The Boltzmann transport equation is the basic equation for solving the transport of charge carrier (electrons, holes) problems in semiconductor devices. The distribution function has been obtained from the solut...

BackgroundIn the field of geological exploration of coal mines, methods such as in-seam seismic exploration, the transient electromagnetic method, and audio-frequency electrical penetration offer unique technical advanta...

Rural communities are increasingly challenged by climate change, declining agricultural productivity, and economic vulnerabilities, highlighting the urgent need for livelihood diversification. This study aims to identify...

IntroductionMenotropins is a mixture of gonadotropin glycoproteins extracted from the urine of postmenopausal women. Its composition is complex, with active components including follicle-stimulating hormone (FSH), lutein...

INTRODUCTION. In 2022, due to the political situation in the world, many foreign brands were forced to leave the Russian market. After some time, some of them returned, undergoing renaming – changing their trade name. ...

Nonlinear wave dynamics play an essential role in understanding energy localization, pulse transmission, and stability events in a variety of physical systems. Inspired by its importance, we study a fourth-order nonlinea...

ObjectiveTo establish a highly sensitive and high-throughput analytical method for the simultaneous determination of 38 organic ultraviolet absorbents （OUVAs） by pass-through solid phase extraction （SPE） coupled ...

The differences between the concepts of “tax planning”, “tax minimization” and “tax optimization” are investigated and it is established that tax minimization is the maximum reduction of all taxes, tax optimi...

This study explores the evolving role of stockbrokers in the context of global financial market transformation and the rapid expansion of digital technologies. We examine how the traditional function of brokers as mere t...

The increasing role of health and quality of life factors in shaping modern socio-economic development models, along with the transformation of consumer behavior, contributes to the growing scale of the wellness economy....

challenges of today caused by the aggravating economic crisis in Ukraine, numerous threats to the national security, in particular the ones resulting from invasion and occupation of the Ukrainian territory by the Russian...

Background. Respiratory infections remain a major global health burden with significant economic impact. The di-versity of viral pathogens and variability in diagnostic approaches complicate etiological verification in l...

ABSTRACT Background Urine protein‐creatinine ratio (UPC) and urine specific gravity (USG) are important measurements in the determination of renal proteinuria and chronic kidney disease. Biological and analytical varia...

This chapter introduces the most relevant concepts about wine field, including terroir, manufacturing process and the Wine Protected Designation as a way ofauthentication. Contents of molecular organic acids, volatile sp...

A stability-indicating high-performance liquid chromatographic (HPLC) and a second-order derivative spectrophotometric (UVDS) analytical methods were validated and compared for determination of simvastatin in tablets. Th...

En este trabajo se describe la validación retrospectiva de las técnicas analíticas espectrofotométricas que han sido empleadas tradicionalmente en la determinación cuantitativa de las prostaglandinas A2 y B2 en extr...

Fast release capsules, containing sertraline hydrochloride, pregelatinized maize starch and microcrystalline cellulose were formulated. For this purpose, different technological assays were elaborated being the formula...