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Background: Type 2 diabetes mellitus (T2DM) involves metabolic disturbances and endothelial dysfunction, raising cardiovascular risk. Objective: To compare the effects of 8 weeks of resistance, endurance, and combined ex...

Background Obese dogs risk poor life quality, creating a need for increased knowledge of metabolism in overweight dogs. Objectives Investigate postprandial metabolic and hormonal responses to a high‐fat mixed‐meal in...

Dez eqüinos foram avaliados durante um processo de indução de desidratação para a avaliação da osmolalidade plasmática calculada (OPC), da osmolalidade plasmática mensurada (OPM) e do osmol gap. A desidratação...

Introduction: Diabetic Neuropathy (DN) is a common and debilitating complication of Diabetes Mellitus (DM), involving the sensory, motor, and autonomic nervous systems, with limited disease-modifying treatment options. E...

Abstract This study aimed to assess the effects of different inclusion levels of canola meal (CM) on growth performance, carcass characteristics, physicochemical properties, and fatty acid composition of Dohne Merino ram...

The present study investigated the role of the N, N{ 0 }-dimethylbiguanide metformin (50 mg/100 g body weight in 0.05 ml water, given orally with a canulla) in the prevention of endocrine and immune disorders provoked by...

ObjectiveTo investigate the predictive value of serum citrullinated histone H3 (CitH3) and thymic stromal lymphopoietin (TSLP) for postoperative wound healing outcomes in patients with pilonidal sinus (PS), and to constr...

OBJECTIVE: It has previously been shown that renal function is impaired in metabolic syndrome (MetS). Microalbuminuria, elevated serum osmolality, and decreased glomerular fi ltration rate (GFR) may indicate some degree ...

Sitagliptin (SIT) is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the effects of incretin hormones, such as Glucose-dependent Insulinotropic Peptide (also known as Gastric Inhibitory Polypeptide, GIP) and Glu...

Abstract Objective To evaluate the effects of vitamin D supplementation in the postpartum period of women with previous gestational diabetes mellitus (GDM). Methods Randomized clinical trials of pregnant women with G...

Abstract Objective To evaluate the prevalence of metabolic syndrome (MetS) in the phenotypes of polycystic ovarian syndrome (PCOS). Methods This was a cross-sectional study involving 111 women aged between 18 and 39 ...

OBJECTIVE: Autonomic nervous system dysfunction (ASD) has been widely observed in patients with type 2 diabetes. 24-hour ambulatory blood pressure (ABP) and heart rate measurements have been found to associate with ASD i...

OBJECTIVE: There are scarce data regarding the relationship between insulin resistance, parathyroid hormone (PTH) and blood pressure (BP) in the literature. This study is aimed to investigate the interrelationships betwe...

Abstract Background Polycystic ovary syndrome (PCOS) is characterised by insulin resistance and hyperandrogenism; whether novel antidiabetic drugs differentially improve these metabolic and reproductive disturbances rema...

BackgroundSecondary hyperlipidemia is a common and serious complication in patients with clinically diagnosed depressive disorders, yet early screening tools are lacking. This study aims to develop and validate a machine...

Abstract Background Diabetic nephropathy (DN) remains a leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD). Tubular biomarkers, such as urinary Netrin-1, are emerging as early indicators of ...

The aim of the present study was to investigate the role of liver in progression of insulin resistance in relation to IGF-I levels in rats with acute hepatotoxicity, induced by carbon tetrachloride (CCl4) and acetaminoph...

Repaglinide is a potent second generation oral hypoglycaemic agent widely used in treatment of non insulin dependent diabetic mellitus. The objective of the present study was to develop sustained release microspheres of...