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Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cholinergic dysfunction, making acetylcholinesterase (AChE) a key therapeutic target. Although Garcinia kola has been widely reported ...

Sperm transfer in spiders is achieved by copulatory organs on the male pedipalps (i.e., copulatory bulbs), which can be simple or a complex set of sclerites and membranes. During copulation, these sclerites can be used t...

Resveratrol, a natural polyphenol, may serve as a potential drug for pulmonary fibrosis (PF). This study uses meta-analysis and machine learning to assess resveratrol's efficacy and optimal treatment on PF animals. Four ...

Plants frequently encounter diverse abiotic stresses, which require precise transcriptional regulation to maintain basic survival plasticity. The BES1 transcription factor family, a key component of brassinosteroid (BR) ...

Rongzhi Huang,1,* Zexu Zhan,1,* Shulin Huang,1 Wenlong Cao,1 Jiehua Li,1 Min Mao2 1Department of Gastrointestinal and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, T...

Abstract Background Outcomes after curative-intent sarcoma surgery vary substantially and are incompletely explained by tumor-centered factors alone. Although CT-based body composition metrics provide objective host-rela...

Yu Luo,1 Suning Huang,1,2 Haichuan Xie,3 Bei Zhang,3 Fei Ma,1– 4 Yanting Lin,1– 4 Yan Ning,1– 4 Jiaman Wu1– 4 1Graduate School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, People’s R...

IntroductionVisual electrophysiology, including electroretinograms (ERG) and visual evoked potentials (VEP), provides a real-time functional assessment of retinal and post-retinal pathways, complementing structural imagi...

Abstract Background Frailty is a known predictor of adverse surgical outcomes, yet its influence on functional recovery trajectories in South Asian settings remains underexplored. This study evaluated the association bet...

IntroductionElevated HbA1c levels, in combination with comorbidities such as diabetes and hypertension, have been linked to increased stroke severity, poorer functional recovery, and higher mortality. However, the predic...

IntroductionAge-related declines in cognitive and motor functions show highly variable trajectories. To better understand the underlying mechanisms, we investigated multivariate associative effects between modifiable vas...

BackgroundTranscriptome−wide association study (TWAS) contributes to discovering novel susceptibility genes related to diseases. Single-cell RNA sequencing (scRNA-seq) has been extensively applied to characterize cellu...

Abstract Background Pulmonary hypertension (PH) is a serious and potentially life-threatening complication of systemic lupus erythematosus (SLE). Functional characterization may facilitate the differentiation of the hete...

Background and objectives: Anterior cruciate ligament (ACL) injuries are common among individuals who lead active lifestyles. A frequently used surgical approach to address this condition is ACL reconstruction (ACLR) uti...

Hyperactivity of the hypothalamic pituitary adrenal (HPA) axis in patients with major depression is one of the most consistent findings in biological psychiatry. Experimental data support the idea that glucocorticoid-med...

ObjectiveTo examine the prevalence of cognitive impairment and factors associated with cognitive impairment among elderly patients with schizophrenia, and to explore potential clinical phenotypes using a clustering appro...

Tithonia diversifolia, known as Mexican sunflower, has been widely used as an herbal medicine to treat diabetes. This study used FTIR fingerprint spectra combined with chemometrics to differentiate T. diversifolia leaves...

Mehmet Zafer Aydın,1 Can Baba Arin,2 Mehmet Kamil Teber,1 Zülfiye Kuzu,1 Mustafa Gök,1 Ishak Ahmed Abdi3 1Department of Cardiology, Kayseri City Training and Research Hospital, Kayseri, Turkey; 2Department o...

Because of resistance development by cancer cells against current anticancer drugs, there is a considerable interest in developing novel antitumor agents. We have previously demonstrated that CIGB-552, a novel cell-penet...

Abstract Slaughterhouse blood is a by-product of animal slaughter that can be a good source of animal protein. This research purposed to examine the functional qualities of the blood plasma from Hanwoo cattle, black goat...

Abstract Background ATF3 was found to play a complex role in various cancers; however, its systematic function in kidney renal clear cell carcinoma (KIRC) and across pan-cancer contexts remained incompletely understood. ...

We present HAlator, a fully automated quantum chemistry (QM) workflow for computing C–H hydricities and explore its potential in predicting the regioselectivity of electron-rich C–H functionalisation reactions. The w...

It can be said that today's civil aviation basics began to be laid in the 1950s. This date is also important as the period in which the rules are being written and at the same time, some system solutions are produced by ...

Relevance. Age-related macular degeneration (AMD) and glaucoma are currently the main causes of irreversible vision loss in developed countries. Purpose. To study the epidemiological and clinical-functional aspects of ...