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The molecular basis of endospore formation in the model gram-positive bacterium Bacillus subtilis has been investigated for over half a century. Here, using high throughput and classical genetic approaches, we performed ...

Heme oxygenase-1 (HO-1), which catalyzes heme degradation releasing iron, regulates several processes related to breast cancer. Iron metabolism deregulation is also connected with several tumor processes. However the reg...

Ensuring microbial safety in drinking water remains a challenge, particularly for ageing infrastructure and complex treatment processes. Because water treatment works sit at the interface between source-water ecosystem i...

Tumors are a deadly condition often triggered by a range of abnormal modifications and genetic abnormalities. Early tumor diagnosis is essential due to the highly concerned nature of the disease. Early detection and trea...

Genome-wide association studies have identified members of the CARD11/MALT1/BCL10 (CBM) complex as susceptibility loci for common allergic disorders, while carriers with rare loss-of-function (LOF) variants in MALT1 or C...

Milk yield test-day records on the first three lactations of 25,500 Holstein cows were used to estimate genetic parameters and predict breeding values for nine measures of persistency and 305-d milk yield in a random reg...

Background: Preterm birth (PTB) is the leading cause of perinatal morbimortality worldwide. Genetic and environmental factors could raise PTB risk. The aim of this study was to analyze the contribution of the statistical...

Post-traumatic stress disorder (PTSD) is a severe neuropsychiatric disorder characterised by re-experiencing, avoidance and hyperarousal. Memory abnormalities manifested as intrusive thoughts and prolonged distressful em...

IntroductionSiderophores are secondary metabolites with high affinity and specificity for iron and play a crucial role in iron acquisition. Vibrio fluvialis, an emerging foodborne opportunistic pathogen of increasing con...

Providing feed is a major input cost in beef production, hence improvements in the efficiency of feed utilisation will reduce the cost of production. Residual feed intake (RFI) is a measure of feed efficiency, and is def...

Numerous treatments for breast cancer have emerged in recent years, influenced by genetic and environmental factors that contribute to the disease's heterogeneity. Breast cancer stem cells are a primary driver of tumor a...

Abstract Background The bark beetle Ips typographus (Coleoptera: Curculionidae: Scolytinae) is a major pest of spruce trees in Central Europe. Its ecological success is mediated by a male-produced aggregation pheromone, ...

ABSTRACT Cells rely on surface receptors to sense and initiate signalling cascades essential for numerous cellular processes, but engineering of synthetic genetic circuits to sense and rewire receptor activities for user...

The most compelling models concerning the peopling of the Americas consider that modern Amerindians share a common biological pattern, showing affinities with populations of the Asian Northeast. The aim of the present st...

Submarine landslides can generate complicated patterns of seafloor relief that influence subsequent flow behaviour and sediment dispersal patterns. In subsurface studies, the term mass transport deposits (MTDs) is common...

The rhizosphere is one of the most dynamic biological environments on Earth. Within this narrow zone surrounding plant roots, plants interact constantly with diverse communities of microorganisms including bacteria, fung...

Tetrahymena es el eucariota unicelular ciliado no patógeno más estudiado y empleado a nivel biotecnológico, pues combina la complejidad de procesos celulares típicos presentes en eucariotas con una gran facilidad de ...

ABSTRACT Background Intervertebral disc degeneration (IVDD), a prevalent spinal disorder, is closely associated with abnormal mechanical stress. The nucleus pulposus (NP), annulus fibrosus (AF), and cartilaginous endplat...

Abstract Juvenile idiopathic arthritis (JIA) is an umbrella term for a group of oligo- and poly-arthritic conditions that develop before 16 years of age. While the exact pathophysiology of JIA is still unknown, both gene...

The purpose of the review is to analyze the results of scientific research on the effect of antioxidant activity of potatoes on human health, to consider modern approaches to breeding potato with high antioxidant activit...

The biological processes on mosquito could be variable in response to local climatic characteristics. The thermal effects on time and the rate larval development, immature survival and adult size in local populations of ...

With the rapid advancement of sequencing technology, third-generation sequencing, particularly single-molecule real-time sequencing and nanopore sequencing, has opened new avenues for the precise prevention and control o...

Abstract Background Cycas panzhihuaensis, as a national first-class protected plant, has long been threatened by dual high-temperature and drought stress. Photosynthesis is a key target of dual high-temperature and droug...

Abstract Zebrafish have the capacity to fully regenerate the heart after an injury, which lies in sharp contrast to the irreversible loss of cardiomyocytes after a myocardial infarction in humans. Transcriptomics analysi...