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ABSTRACT Myocardial ischemia‐reperfusion (MI/R) injury remains a critical challenge in cardiovascular therapeutics, with metabolic‐inflammatory signaling axis emerging as a critical mediator of pathological outcomes....

BackgroundRecurrent acute kidney injury (rAKI) is a common complication among critically ill patients and is associated with progressive renal deterioration and increased long-term morbidity. Iron deficiency anemia (IDA)...

Objective To identify early clinical predictors associated with dysphagia and delayed swallowing recovery in patients with traumatic brain injury (TBI). Methods In this retrospective study, we enrolled adult TBI patients...

The antiphospholipid antibody syndrome (APS) is characterized by antibodies directed either at plasma proteins bound to phospholipids or at the phospholipids themselves. APS is referred to as primary when it occurs alone...

Abstract Deoxynivalenol (DON), a prevalent Fusarium mycotoxin, poses a significant threat to intestinal health in piglets. This study established a deoxynivalenol (DON) intoxication model in piglets, revealing compromise...

With the widespread application of chemotherapy, immunotherapy, and targeted therapy, cardiotoxicity associated with anti-tumor treatment has gained increasing attention. Drug-induced cardiac injury can significantly imp...

Objective: This study aimed to evaluate the prevalence of hypoalbuminemia and hyperuricemia, and investigate uric acid albumin ratio association with mortality and acute kidney injury (AKI) in critically ill patients. ...

Shenfu Injection (SFI) is a standardized botanical drug derived from two Chinese medicinal herbs Panax ginseng C.A.Mey. and Aconitum carmichaelii Debeaux. SFI is historically used for “restoring yang and reversing coll...

Abstract Objective Acute kidney disease (AKD) describes acute or subacute renal damage and/or loss of kidney function between 7 and 90 days after AKI initiation. Because there are few reports on AKD in older patients, t...

OBJECTIVE: To determine the incidence and outcome of acute kidney injury (AKI) in critically ill patients and to evaluate RIFLE criteria in critically ill patients. Prospective observational study. MATERIAL and METHOD...

Introduction: Complete traumatic disruption of the anorectal sphincter in children is rare and surgically challenging. High-grade penetrating injuries with delayed presentation and heavy fecal contamination carry signifi...

ABSTRACT One lung ventilation (OLV) often results in trauma to the unventilated contralateral lung. This study aims to evaluate the effects of different OLV regimens on the injury of the unventilated contralateral lung t...

Sporisorium reilianum has been commonly used for its high nutritional value, with its main active ingredient being polysaccharides. However, the high molecular weight (Mw) of polysaccharides limits their functionality, a...

Abstract Background Tacrolimus-induced interstitial lung injury (TI-ILI) is a rare but potentially fatal adverse effect of calcineurin-inhibitor therapy. To our knowledge, TI-ILI has not previously been reported in a pae...

The process of adapting to a physical disability is complex and multi-dimensional. It is influenced by many variables that affect adequate life adjustment and psychological wellbeing. This study addresses the specific ef...

Abstract Background The ingestion of grapes or raisins has been reported to cause acute kidney injury (AKI) in dogs, with a clinical picture dominated by early gastrointestinal signs and rapidly developing uremia. Ataxia...

Abstract Background Effective strategies for managing ischemia-reperfusion injury in acute myocardial infarction remain limited, despite advances in reperfusion therapy. Transcutaneous electrical nerve stimulation (TENS)...

In this study, the importance of urinary N-acetyl β-u glucosaminidase (NAG) as an index of renal injury was assessed inpatients with liver cirrhosis. The study was carried out on 14 cirrhotic patients without primary ...

ABSTRACT Background Cardiomyopathy is one of the complications of diabetes, among which myocardial fibrosis is the most typical feature. Ubiquitin‐specific peptidase 18 (USP18) is a deubiquitinating enzyme. Multiple st...

Abstract Four 2‐month‐old foals were presented to an equine hospital with acute kidney injury caused by Leptospira interrogans infection. Clinical signs were nonspecific and included lethargy, fever, and unwillingnes...

Background: Hepatic metabolic disorders are closely associated with obesity and are characterized by systemic inflammation and liver injury. Moringa oleifera fruit contains various bioactive compounds with potential anti...

Abstract Background In basketball, quadriceps strains and contusions are common due to the muscle’s role in knee extension and hip flexion, with the rectus femoris most prone to injury because it crosses both joints, m...

Thrombotic microangiopathy is a pathological condition caused by several factors including drugs, and characterized by endothelial injury and small vessel occlusion. It may cause severe acute kidney injury. Everolimus, a...

Background: Bisphenol A (BPA), a widely used industrial chemical, is a well-known endocrine disruptor linked to testicular damage and impaired male reproductive function. Fucoxanthin (Fx), a marine carotenoid with potent...