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Dois trabalhos foram conduzidos para estimativa do consumo individual de vacas em lactação alimentadas em grupo. No primeiro, para validar a metodologia, foram utilizadas oito vacas, alojadas em baias individuais receb...

Abstract Primary temperate forests serve as a natural framework for studying linkages between vegetation, soil properties and microbial communities under minimal human disturbance. Here, we characterize how soil bacteria...

The digestive and metabolic characteristics at the biochemical level underlying between-habitat dietary shift of the SW Atlantic euryhaline burrowing crab Neohelice granulata under natural conditions are unknown. We made...

Background The field of extracellular vesicles (EVs) has advanced considerably in recent years with new findings stemming from technical improvements in their isolation and characterization, expanding their potential as ...

Abstract Background This letter engages with the seminal review by Argyrakopoulou et al. Obesity and the Gut-Brain Axis in Type 1 Diabetes Mellitus: Terra Incognita? Curr Obes Rep, https://doi.org/10.1007/s13679-025-0065...

Abstract Polyunsaturated fatty acids (PUFAs) are important nutrients that play critical roles in sea urchin reproduction and early development. Strongylocentrotus intermedius, the only commercially cultured sea urchin sp...

Abstract Background The MARS PETCARE BIOBANK™ (MPB) is a study recruiting pets visiting Mars Veterinary Health hospitals in the USA over a ten-year period, with the aim of analysing longitudinal data from thousands of ...

OBJECTIVE: Type 2 diabetes mellitus (T2D) is a chronic metabolic disorder requiring effective management. Ipragliflozin (SGLT-2 inhibitor) and sitagliptin (DPP-4 inhibitor) are commonly used treatments with distinct mech...

Abstract Objective Streptococcus shenyangsis is a recently reported member of the genus Streptococcus, rarely detected in the human oral cavity and for which genomic information remains limited. To broaden our understand...

Background. Type 2 diabetes is a chronic metabolic disorder associated with impaired insulin secretion and insulin resistance, leading to persistent hyperglycemia and multiple complications. Despite advances in pharmacot...

Background: Creatine is one of the most commonly used ergogenic supplements. However, many myths and misconceptions about creatine supplementation regarding renal function are still popular even among medical professiona...

Abstract Simultaneous inhibition of DNA gyrase and topoisomerase IV (Topo IV) is a primary pharmacological strategy to enhance antibacterial efficacy and markedly reduce the emergence of antibiotic resistance. In this re...

IntroductionHormone-associated cancers use steroid metabolism to grow and avoid the immune system, while traditional treatments have to deal with drug resistance and systemic toxicity.MethodsThis study is mainly divided ...

IntroductionProbiotics have demonstrated positive effects on obesity and type 2 diabetes (T2D) in various studies. Postbiotics, specifically nonliving bacterial lysates derived from cell walls and DNA, are increasingly r...

Abstract Background The addition of calcium to resuscitation fluids is a common practice in horses, but studies evaluating the effects of calcium supplementation are limited. In healthy horses, decreases in heart rate an...

Abstract Objective To identify the impact of redox imbalance on the clinical evolution of patients with polycystic ovary syndrome and carry out a qualitative and quantitative projection of the benefits of vitamin D sup...

BackgroundGestational diabetes mellitus (GDM) is an increasingly important contributor to maternal and neonatal morbidity in Africa, yet the evidence base remains fragmented across settings and research domains. This stu...

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that affects women in their reproductive age. Recent studies have shown that genes have an important role in the etiology of PCOS. However, th...

Abstract Background Mesenchymal stem cells (MSCs) have become a promising treatment of liver fibrosis which is a key process in liver diseases. Recent studies have shown that transplanted MSCs undergo rapid apoptosis and...

Abstract Background Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that is increased in azotemic cats with chronic kidney disease (CKD) and predictive of the onset of azotemia in older cats. The introducti...

BackgroundThe intestinal barrier is a critical interface between the host and the external environment, and growing evidence indicates that bidirectional crosstalk between the gut microbiota and the intestinal barrier is...

Background. The human gastrointestinal tract contains a large community of microorganisms, known as the gut microbiota. Their metabolic and immunological functions influence host physiology. Disruption of this community,...

Abstract Background Migraine is a very common chronic neurological disorder associated with severe disability and significant social burden worldwide. Beyond recurrent headache attacks, increasing evidence indicates that...

ABSTRACT Transcriptional regulation of metabolic operons is important for optimal carbohydrate use and for mitigating the accumulation of toxic intermediates. Here, we characterize SL1344_3500, encoding a putative IclR-l...