Buscar recursos académicos

Abstract The development of trustworthy AI models is crucial, particularly for critical medical applications such as brain tumor detection using MRI images. However, medical images are being increasingly targeted by adve...

Parkinson’s disease (PD) is characterized by profound metabolic disturbances in the brain, yet how these alterations vary across brain regions and respond to neuroprotective intervention remains poorly understood. Here...

In the growing diversity of human induced pluripotent stem cell (iPSC)-derived models of brain development, we present here a novel method that exhibits 3D cortical layer formation in a reproducible topography of minimal...

Abstract Purpose Prader-Willi Syndrome (PWS) is a rare genetic disorder with a heterogeneous phenotype, caused by loss of expression of genes on the paternally inherited chromosome 15q11.2-15q13.3, primarily due to pater...

Perinatal asphyxia (PA) is a primary cause of neonatal morbidity, with persistent neurological sequelae, associated with mitochondrial dysfunction and redox imbalance. The lack of experimental approaches for region-speci...

There is a growing interest in the potential of mesenchymal stem cells (MSCs) for implementing regenerative medicine in the brain as they have shown neurogenic and immunomodulatory activities. We assessed the effect of i...

Lucie Bartova,1 Mara Lisa Beuster,2 Bruno Bonetti,3 Giuseppe Maina,4,5 Pedro Morgado,6 Johan Nyberg7 1Department of Psychiatry and Psychotherapy, Clinical Division of General Psychiatry, and Comprehensive Center for Clin...

Abstract The dissemination route of brain metastases dictates their spatiotemporal distribution, but whether it alters the ultrastructural state of the blood-tumor barrier remains unresolved. Here, we compared a modified...

Recent historical works dealing with the changing role of emotions in social and private life over centuries present a challenge to any philosophical or scientific theory aiming to grasp the essence of emotions. The pape...

BackgroundCurrent prognostic models for cerebral venous sinus thrombosis (CVST) inadequately predict long-term cognitive and functional outcomes, focusing primarily on survival. We aimed to develop and validate a simple,...

The misuse of opioids has reached epidemic proportions over the last decade, with over 2.1 million people in the United States suffering from substance use disorders related to prescription opioid pain relievers. This in...

Abstract Brain pericytes are mediators of neuroinflammation, as evidenced in vitro, in animal models and humans. We and others have identified the platelet-derived growth factor (PDGF)-BB -PDGF receptor beta (PDGFRB) pat...

ABSTRACT Background Current diagnosis of brain disease in dogs is dependent on imaging and cerebrospinal fluid (CSF) analysis, including total nucleated cell counts and albumin concentrations. Hypothesis/Objectives To de...

Abstract Accumulation of amyloid beta 1–42 (Aβ42) peptide in the extracellular space in the brain is a major observation in Alzheimer’s Disease (AD)-related pathology. Astrocytes are known to play pivotal role in cl...

"This paper presents a supervised classification method to accurately detect epileptic brain activity in real-time from electroencephalography (EEG) data. The proposed method has three main strengths: it has low computat...

Introduction According to modern scholars (N. Maslova, B. Astafiev), one of the important reasons for the global planetary crisis, including modern educational system in particular, is violation of the conformity of natu...

Abstract The heart-brain axis is a significant contributor to morbidity and mortality following ischemic injury. Pathological and psychological changes in the heart can lead to anxiety, cognitive impairment, and brain in...

El concepto de reserva cerebral y cognitiva (RCC) fue establecido con el objeto de explicar por qué y cómo ciertos individuos, pese a estar afectados por una patología cerebral, no expresan las alteraciones cognitivas...

Background and purposeWe observed that some late-term fetal prenatal magnetic resonance imaging (MRI) scans revealed normal brain structures but exhibited diffuse hyperintense signals on T2-weighted imaging (T2WI) in the...

Introduction. Human behavior and by extension and organizational behavior becomes intelligible, adaptable and with the possibility of optimization if analyzed from the perspective of development and bio-psychological evo...

Abstract Nonergodicity and Simpson’s paradox present significant, yet underappreciated challenges in cognitive neuroscience. Leveraging brain imaging and behavioral data from over 4000 individuals and a Bayesian comput...

"Currently, simulations of the induced currents in the brain produced by transcranial magnetic stimulation (TMS) are used to elucidate the regions reached by stimuli. However, models commonly found in the literature are ...

Abstract Probiotics are functional microorganisms that exhibit various biological activities, such as allergic reactions, inflammation, and aging. The aim of this study is to evaluate the effects of Bifidobacterium lacti...

Abstract Background The current AJCC staging system for breast cancer categorizes all distant metastases under a monolithic M1 designation, failing to capture profound heterogeneity in outcomes. This study aimed to devel...