NODOVOX | Discovery

Perubahan morfologi sel HeLa setelah paparan ekstrak etanolik Curcuma longa

Artículo

Acceso abierto Artículo DOAJ

Perubahan morfologi sel HeLa setelah paparan ekstrak etanolik Curcuma longa

Suryani Hutomo et al · faculty of dentistry universitas gadjah mada · 2017 · ISSN 2460-0164

Cell morphological changes on HeLa cells after Curcuma longa etanolik extract exposure. Curcuma is mostly found in the areas with tropical and sub-tropical climate, and is one of original plants of Southeast Asia. In Ind...

LCC TENDOkRlbnRpc3RyeQ~~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Sclerocorneal limbal stem cell autograft transplantation in dogs Transplante autógeno de células tronco do limbo esclerocorneal em cães

Artículo

Acceso abierto Artículo DOAJ

Sclerocorneal limbal stem cell autograft transplantation in dogs Transplante autógeno de células tronco do limbo esclerocorneal em cães

A.T.J. Brunelli et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2007 · ISSN 0102-0935

The effects of sclerocorneal limbal stem cell autograft transplantation in dogs with corneal wounds were studied. Eighteen dogs were divided in two groups (GI and GII). The animals of GI (n=12) underwent limbal transplan...

LCC LCC:Animal cultureIdioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Thyroid hormone action on innate immunity

Artículo

Acceso abierto Artículo CONICET Digital

Thyroid hormone action on innate immunity

Montesinos, Maria del Mar et al · Frontiers Media S.A · 2019 · ISSN 1664-2392

The interplay between thyroid hormone action and the immune system has been established in physiological and pathological settings. However, their connection is complex and still not completely understood. The thyroid ho...

Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Trypanosoma cruzi Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease

Artículo

Acceso abierto Artículo CONICET Digital

Trypanosoma cruzi Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease

Girard, Magalí Celeste et al · Frontiers Media · 2021 · ISSN 2235-2988

The clinical evolution of patients with chronic Chagas disease (CCD) is mainly associated with an excessive inflammation and a defective immunomodulatory profile caused by the interaction between T. cruzi and the host. R...

Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4

Artículo

Acceso abierto Artículo CONICET Digital

Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4

Cooke, Mariana et al · American Society for Biochemistry and Molecular Biology · 2011 · ISSN 1936-1948

Acyl-CoA synthetase 4 (ACSL4) is implicated in fatty acid metabolism with marked preference for arachidonic acid (AA). ACSL4 plays crucial roles in physiological functions such as steroid synthesis and in pathological pr...

Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

A First-in-Human Base Edit Gene Therapy for CD40L Deficiency X-Linked Hyper IgM (XHIGM) Syndrome

Artículo

Material complementario disponible Artículo DOAJ

A First-in-Human Base Edit Gene Therapy for CD40L Deficiency X-Linked Hyper IgM (XHIGM) Syndrome

Suk See De Ravin et al · Rockefeller University Press · 2026 · ISSN 3065-8993

CD40L-deficient X-linked hyper IgM (XHIGM) syndrome is characterized by defective B cell class switching, deficiency of immunoglobulins G, A, and E, plus other immune abnormalities due to disrupted CD40L–CD40 interacti...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Aluminum suppresses humoral immunity through counteracting oxidative stress and repair effects of iron supplementation

Artículo

Material complementario disponible Artículo DOAJ

Aluminum suppresses humoral immunity through counteracting oxidative stress and repair effects of iron supplementation

Yihuai LIANG et al · Editorial Committee of Journal of Environmental and Occupational Medicine · 2026 · ISSN 2095-9982

BackgroundAluminum (Al) is a lightweight metal that is widely present in the environment and the human body. It has been documented to cause various adverse health effects including the suppression of humoral immunity.Ob...

LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~; TENDOlRveGljb2xvZ3kuIFBvaXNvbnM~Idioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Anticancer potential of Curcuma caesia: induction of DNA damage and apoptosis in cervical cancer

Artículo

Acceso abierto Artículo DOAJ

Anticancer potential of Curcuma caesia: induction of DNA damage and apoptosis in cervical cancer

Megha Radhakrishnan et al · BMC · 2026 · ISSN 2662-7671

Abstract Background Cervical cancer remains the fourth most common malignancy among women worldwide, with limited therapeutic success in advanced and recurrent stages. Conventional treatments, including radiotherapy and ...

LCC TENDOk90aGVyIHN5c3RlbXMgb2YgbWVkaWNpbmU~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

CS2164 combined with radiation suppressed tumor growth via γ-H2AX persistence and ROS accumulation

Artículo

Acceso abierto Artículo DOAJ

CS2164 combined with radiation suppressed tumor growth via γ-H2AX persistence and ROS accumulation

Shun-li Peng et al · BMC · 2026 · ISSN 1471-2407

Abstract Background CS2164 is an oral multi-target inhibitor that targets angiogenesis-related kinases, mitosis-related kinases, and chronic inflammation-related kinases. However, the added clinical benefit of CS2164 com...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Chemerin Promotes Oral Squamous Cell Carcinoma Progression via NLRP3-Mediated Pyroptosis and the GSDMD-N Pathway

Artículo

Acceso abierto Artículo DOAJ

Chemerin Promotes Oral Squamous Cell Carcinoma Progression via NLRP3-Mediated Pyroptosis and the GSDMD-N Pathway

Xuan Zhang et al · Elsevier · 2026 · ISSN 0020-6539

ABSTRACT: Introduction and aims: Oral squamous cell carcinoma (OSCC) is a common malignant tumour of the head and neck region. In recent years, the relationship between pyroptosis and tumours has received increasing att...

LCC TENDOkRlbnRpc3RyeQ~~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

CircSPARC mediates an immunosuppressive tumor microenvironment by regulating the miR-199a-5p/LASP1 axis in non-small cell lung cancer

Artículo

Acceso abierto Artículo DOAJ

CircSPARC mediates an immunosuppressive tumor microenvironment by regulating the miR-199a-5p/LASP1 axis in non-small cell lung cancer

Chengsheng zhang et al · BMC · 2026 · ISSN 1471-2466

Abstract Non-small cell lung cancer (NSCLC) is a major cause of cancer-related mortality globally, linked to an immunosuppressive microenvironment. Circular RNA circSPARC is crucial in cancer, but its function in NSCLC r...

LCC TENDOkRpc2Vhc2VzIG9mIHRoZSByZXNwaXJhdG9yeSBzeXN0ZW0~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Combined B Cell Aplasia and Hypereosinophilia as a Complication of Lamotrigine Therapy

Artículo

Material complementario disponible Artículo DOAJ

Combined B Cell Aplasia and Hypereosinophilia as a Complication of Lamotrigine Therapy

Katherine Michaelis et al · Rockefeller University Press · 2026 · ISSN 3065-8993

BackgroundAlthough drug rash with eosinophilia and systemic symptoms (DRESS) and anticonvulsant hypersensitivity syndrome are well-known complications of anti-seizure medications (ASMs), lesser-known immunologic complica...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Correlation of Activated-Inflammatory T Cell Subtypes in Patients Tested for Lymphocyte Immunodeficiency

Artículo

Acceso institucional disponible Artículo DOAJ

Correlation of Activated-Inflammatory T Cell Subtypes in Patients Tested for Lymphocyte Immunodeficiency

Charles Lutz · Rockefeller University Press · 2026 · ISSN 3065-8993

CD19negCD20dim T cells are mostly CD8+ and predominantly express memory markers. Based on the literature, they may be a subset of inflammatory T cells rather than a transient activated state. I postulated that CD19negCD2...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Acceso institucional disponibleEl acceso puede requerir institución, suscripción, proxy, VPN o autenticación.

Institucional

Abrir acceso Ficha bibliográfica

Cross-talk between microglia and neurons regulates HIV latency.

Artículo

Material complementario disponible Artículo DOAJ

Cross-talk between microglia and neurons regulates HIV latency.

David Alvarez-Carbonell et al · Public Library of Science (PLoS) · 2019 · ISSN 1553-7366

Despite effective antiretroviral therapy (ART), HIV-associated neurocognitive disorders (HAND) are found in nearly one-third of patients. Using a cellular co-culture system including neurons and human microglia infected ...

LCC LCC:Immunologic diseases. Allergy; LCC:Biology (General)Idioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Determinants of Fate Progression Beyond the Human Tfh Cell Stage

Artículo

Acceso abierto Artículo DOAJ

Determinants of Fate Progression Beyond the Human Tfh Cell Stage

Suzanna Rachimi et al · Rockefeller University Press · 2026 · ISSN 3065-8993

T follicular helper (Tfh) cells have been reported to have multiple trajectories, including terminally differentiated Tfh, memory-like circulatory Tfh (cTfh), and, most recently, induced T follicular regulatory (iTfr) ce...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Effects on Goat Meat Extracts on α-Glucosidase Inhibitory Activity, Expression of Bcl-2-Associated X (BAX), p53, and p21 in Cell Line and Expression of Atrogin-1, Muscle Atrophy F-Box (MAFbx), Muscle RING-Finger Protein-1 (MuRF-1), and Myosin Heavy Chain-7 (MYH-7) in C2C12 Myoblsts

Artículo

Acceso abierto Artículo DOAJ

Joohyun Kang et al · Springer Nature · 2023 · ISSN 2636-0772

Abstract This study examined the α-glucosidase inhibitory, and apoptosis- and anti-muscular-related factors of goat meat extracts from forelegs, hind legs, loin, and ribs. The goat meat extracts were evaluated for their...

LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Elucidating the Pathogenesis of Chronic Norovirus in Inborn Errors of Immunity: Lessons from Single-Cell Transcriptomics of Biopsies and Patient-Derived Organoids

Artículo

Acceso abierto Artículo DOAJ

Elucidating the Pathogenesis of Chronic Norovirus in Inborn Errors of Immunity: Lessons from Single-Cell Transcriptomics of Biopsies and Patient-Derived Organoids

Jessica Durkee-Shock et al · Rockefeller University Press · 2026 · ISSN 3065-8993

Chronic norovirus infection (CNI) causes significant morbidity and mortality in immunocompromised patients, including those with inborn errors of immunity (IEI). Gastrointestinal samples from patients with CNI demonstrat...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Enhancing Pediatric Cancer Survival in Indonesia: The Role of CAR T Cell Therapy

Artículo

Material complementario disponible Artículo DOAJ

Enhancing Pediatric Cancer Survival in Indonesia: The Role of CAR T Cell Therapy

Muhammad Al Azhar et al · Dharmais Cancer Hospital - National Cancer Center · 2024 · ISSN 1978-3744

Pediatric cancer poses a major health challenge globally, especially in low-middle-income countries like Indonesia. The survival rate of pediatric cancer in many high-income countries (HICs) reaches 90%, while it only ra...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Exosome-mediated delivery of miRNA-1290 inhibitor enhances JNK-dependent tissue-resident memory T cell immunity in prostate cancer

Artículo

Acceso abierto Artículo DOAJ

Exosome-mediated delivery of miRNA-1290 inhibitor enhances JNK-dependent tissue-resident memory T cell immunity in prostate cancer

Bin Liang et al · Nature Portfolio · 2026 · ISSN 2045-2322

Abstract Prostate cancer (PCa) is a leading malignancy in men, particularly challenging in its advanced stages due to treatment resistance and immune evasion. MicroRNA-1290 (miR-1290) was identified to be implicated in t...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection

Artículo

Acceso abierto Artículo CONICET Digital

GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection

Ortiz Wilczyñski, Juan Manuel et al · Public Library of Science · 2020 · ISSN 1553-7366

Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are kn...

Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Geranylgeraniol Modulates Inflammatory and Metabolic Pathways but Not IgD Biology in Mevalonate Kinase Deficiency

Artículo

Material complementario disponible Artículo DOAJ

Geranylgeraniol Modulates Inflammatory and Metabolic Pathways but Not IgD Biology in Mevalonate Kinase Deficiency

Anna Sediva et al · Rockefeller University Press · 2026 · ISSN 3065-8993

ObjectivesMevalonate kinase deficiency (MKD) is a metabolic disorder caused by a block in the mevalonate pathway, leading to impaired synthesis of cholesterol and isoprenoids. Clinically, MKD presents with recurrent infl...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Human Herpesvirus 6 (HHV-6) Infection Impairs T Cell Development in Children with Congenital Athymia Who Have Received Allogeneic Processed Thymus Tissue–agdc (RETHYMIC)

Artículo

Material complementario disponible Artículo DOAJ

Human Herpesvirus 6 (HHV-6) Infection Impairs T Cell Development in Children with Congenital Athymia Who Have Received Allogeneic Processed Thymus Tissue–agdc (RETHYMIC)

Jack Ringel et al · Rockefeller University Press · 2026 · ISSN 3065-8993

BackgroundCongenital athymia (CA) is a rare T cell immune deficiency, fatal without curative treatment with allogeneic processed thymus tissue–agdc (RETHYMIC) implantation (here termed CTTI). The rate and extent of T c...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Human Inherited RORγT Deficiency: Genetic Heterogeneity, Immunological Impact, and Clinical Homogeneity

Artículo

Material complementario disponible Artículo DOAJ

Human Inherited RORγT Deficiency: Genetic Heterogeneity, Immunological Impact, and Clinical Homogeneity

Iris Fagniez et al · Rockefeller University Press · 2026 · ISSN 3065-8993

We previously reported that inherited human retinoic acid-related orphan receptor gamma T (RORγT) deficiency underlies mycobacterial disease and chronic mucocutaneous candidiasis (CMC) in seven patients from three ances...

LCC LCC:Immunologic diseases. AllergyIdioma eng

Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.

Material complementario

Abrir material Ficha bibliográfica

Hypothyroidism impacts mammary tumor-associated adipose tissue and breast cancer epithelial cell dialogue

Artículo

Acceso abierto Artículo CONICET Digital

Hypothyroidism impacts mammary tumor-associated adipose tissue and breast cancer epithelial cell dialogue

Zyla, Leila Ester et al · Elsevier France-Editions Scientifiques Medicales Elsevier · 2025 · ISSN 0300-9084

Thyroid hormones play a key role in adipose tissue development and function. Hypothyroidism (HypoT) can delay mammary tumor development in rats, possibly by altering mammary adipose tissue (MAT) and its interaction with ...

Idioma eng

Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.

Open Access

Disponible en línea Ficha bibliográfica

Anterior 2 345 Siguiente

Buscar recursos académicos

Resultados