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Abstract Objectives Gastrointestinal neuroendocrine neoplasms (GI-NENs) exhibit heterogeneity in biological behavior, making it difficult to predict prognosis. We established the P Grade based on 68Ga-DOTANOC and 18F-FDG...

ObjectiveThe prognostic implications of surgical outcomes in older adults with ovarian cancer remain unclarified. This study aimed to describe temporal trends in surgical management and examine the association between su...

Abstract Introduction Tuberculosis infection (TBI) is a great barrier to tuberculosis control. Previous large-scale study had revealed that the TBI rate was between 13% and 20% for the general population in China. Howeve...

ABSTRACT Background and Aims Obstructive sleep apnea (OSA) is a prevalent sleep disorder linked to cardiovascular diseases and is highly prevalent, especially in the elderly population. This study aimed to investigate th...

The safety concept primarily examines the most fatal (resulting in dead passengers) accidents of aviation history in this study. The primary causes of most fatal accidents are; human, technical, and sabotage/terrorism fa...

BackgroundThe prevalence of type 2 diabetes is continuously increasing, and optimizing the treatment strategies for diabetes is an important clinical issue. SGLT2 inhibitors (SGLT2i) and DPP-4 inhibitors (DPP-4i) are two...

ObjectiveThe aim of the study was to examine the relationships between dietary intake of amino acids and the risk of hypertension and to find some important amino acids as the targets of intervention in Chinese children ...

ObjectiveTo explore the effects of different serum potassium levels on the 28-day prognosis of elderly patients with sepsis. MethodsA retrospective analysis was conducted on the clinical data and laboratory indicators wi...

ObjectiveTo investigate the association of serum N-terminal pro-brain natriuretic peptide (NT-proBNP), red cell distribution width (RDW), homocysteine (Hcy), and clinical parameters with new-onset atrial fibrillation (NO...

Abstract Objective This study aimed to systematically identify and validate KIF15 as a potential diagnostic and prognostic biomarker in colon cancer (CC) using integrated bioinformatics analyses. We further explored its ...

BackgroundClinically, cardiotoxicity defined by reduced left ventricle ejection fraction (LVEF) in cancer therapy could miss the onset of tissue-level myocardial changes. In this study, we aimed to use late gadolinium en...

BackgroundSarcopenia has a high incidence in older patients with sepsis and is closely associated with poor prognosis, but its metabolic characteristics under this specific stress state remain unclear. This study aims to...

Background & Aims: Atezolizumab/bevacizumab (A/B) and durvalumab ± tremelimumab (DT/D) are preferred first-line regimens for the treatment of hepatocellular carcinoma (HCC). Although both therapies share an anti-PD-...

Abstract Background Individuals with abnormal glucose metabolism are at high risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD). Severe hepatic steatosis represents a critical transition ...

Abstract Background Mental health disorders, including depression, pose a significant global health threat, particularly among specific populations, such as men with infertility. No published data on depression prevalenc...

Realizar pronósticos sobre precios resulta muy importante no sólo para la toma de decisiones de un sector productivo, sino también para la elaboración de políticas públicas; ya que permite reducir la incertidumbre ...

ABSTRACT Background Achievement of an efficient and equitable health care system through coverage of health insurance is an important instrument to break up the vicious circle of poverty and ill health. This study sought...

Di Wang,1,* Wei Zhang,2,* Xudong Gao,2 Huifang Kong,2 Huixin Zhang,2 Jiagan Huang,2 Meng Zhang,1 Xiujuan Chang,2 Zhen Zeng1,2 1 302 Clinical Medical School, Peking University, Beijing, People’s Republic...

The objective of this work was to develop a multivariate strategy to optimize tablet manufacturing employing mephenesin as model drug. The process variables for granulation step were binders and lubricants types, while ...

Current performance prediction analytical models try to characterize the performance behavior of actual machines through a small set of parameters. Due to different factors, the predicted times suffer substantial deviati...

Los análisis de Fourier permiten caracterizar el contorno del diente a partir de un número determinado de puntos y extraer una serie de parámetros para un posterior análisis multivariante. No obstante, la gran comple...

A calibração multivariada constitui uma ferramenta analítica que possibilita a determinação de fármacos em formas farmacêuticas, mesmo na presença de interferentes e utilizando toda informação química relevant...

En esta tesis, proponemos una clase de estimadores robustos para modelos lineales multivariados. Basados en el enfoque de la MM estimación (Yohai 1987, [36]), calculamos los coeficientes de regresión y la matriz de cov...

Raman spectroscopy in combination with partial least-squares (PLS) regression method was developed for sulphamethoxazole (SMZ) and trimethoprim (TMP) simultaneous determination in powder mixtures. The calibration set was...