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Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...

Kidney diseases, related to high morbidity and mortality, are one of the diseases that should be primarily investigated. Development of acute and chronic kidney diseasesis due to lack of functioning renal repair mechan...

Stings by Thalassophryne nattereri are responsible for envenomation of fishermen in north-eastern Brazil. Its venom induces prominent local tissue damage, characterized by pain, oedema and necrosis. The pathogenesis of a...

Extreme indoor and outdoor conditions in patients’ places of stay (hot or cold air and changes in humidity) lead to weakening of the lipid barrier function and disproportionate epidermal microbiota which results in a l...

Abstract As global efforts to address climate change continue, digital assets such as regenerative finance (ReFi) and renewable energy tokens are gaining attention in the context of financing decarbonization and clean en...

Abstract Background The ability to guide stem cells toward the bone-forming lineage is a fundamental aspect of regenerative medicine. Conventional protocols for osteogenic differentiation of mesenchymal stem cells typica...

Abstract Telomeres, the ends of eukaryotic chromosomes, protect genome integrity and enable cell proliferation. Maintaining optimal telomere length in the germline and throughout life limits the risk of cancer and enable...

Latar Belakang. Kerusakan periodontal yang signifikan secara klinis selama dewasa atau awal masa dewasa dikenal sebagai periodontitis agresif. Perawatan standar scaling dan root planing sering kurang memuaskan hasilnya s...

Various biomaterials have been utilized as additional material to help tissue regeneration in the open flap debridement (OFD) procedure. Platelet-rich fibrin (PRF) is an autologous platelet concentrate that contains many...

Abstract One of the biggest challenges in tissue engineering and regenerative medicine is to ensure oxygen supply of cells in the (temporary) absence of vasculature. With the vision to exploit photosynthetic oxygen produ...

Primary human intestinal epithelial cells (IECs) require microenvironments that reproduce various in vivo cues to maintain survival, differentiation, and function in vitro. In this study, we investigated how intestinal s...

Abstract Background Signaling molecules play a critical role in regulating stem cell-mediated bone regeneration. In this study, we investigated the effect of EphB4 gene transfection on the osteogenic differentiation and ...

Stem cell therapy, a highly recognized approach in the field of regenerative medicine, is known for its potential to stimulate the self-healing process of the body using stem cells or their derivatives, in which urine-de...

Objective: To summarize and contextualize current and future perspectives in the surgical treatment of lymphedema, exploring new techniques and technologies, integrated treatment modalities, and their real-time clinical ...

Since lithium (Li+) plays roles in angiogenesis and osteogenesis, the localized and controlled release of Li+ ions from bioactive glasses (BGs) represents a promising alternative therapy for bone regeneration. This chapt...

Fil: Cardozo, Alejandra Johana. Hospital Italiano; Argentina. Como el sistema nervioso tiene una capacidad limitada de autorreparación, y la neurogénesis en el adulto está restringida a ciertas regiones del cerebro, ...

Tesis de Licenciatura Las células madre mesenquimales son células madre adultas que pueden originar principalmente derivados de la línea mesodérmica, como osteocitos, adipocitos y condrocitos. En numerosas especies, ...