COBT: a gene-based rare variant burden test for case-only study designs using aggregated genotypes from public reference cohorts
Artículo
Acceso abierto
Artículo
DOAJ
Abstract Rare disease gene discovery is limited by small cohorts and the frequent absence of matched controls. We present the Case-Only Burden Test (COBT), a gene-based burden test for case-only designs accounting for mu...
LCC LCC:Medicine; LCC:GeneticsIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access