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Abstract Background Sub-Saharan Africa (SSA) has been witnessing a persistent increase in the burden of cardiovascular diseases (CVD), such as stroke and heart disease, over several decades. A key driver of this burden h...

Abstract Introduction We conducted a network meta-analysis of randomized trials to assess the effect of different exercises on the renal and cardiovascular function of patients with chronic kidney disease not receiving d...

Abstract Background Epidemiological data consistently associate low vitamin D status with elevated cardiovascular risk, yet causal mechanisms remain contested. Methods This review synthesized evidence through a protocol-...

Abstract Current treatment for atherosclerotic cardiovascular diseases (ASCVD) mainly focuses on the modification of systemic risk factors, such as hyperglycemia and hyperlipidemia. Despite significant efforts and expans...

Abstract Background Most climate and health studies are based on a single extreme weather event and do not consider multiple physical processes across spatial and temporal scales. Our aim was to explore the current lands...

Abstract Background The holistic health of children, encompassing physical, psychological, and social domains, plays a crucial role in long-term societal development. However, evidence suggests that many young people eng...

Abstract Background/objectives Cardiovascular diseases (CVDs), particularly myocardial infarction (MI) and heart failure (HF), remain global causes of morbidity and mortality, despite the current treatment options. Stem ...

Abstract Background Surgeons work in high-pressure, high-risk environments, which can lead to physical and mental health challenges. Physical activity (PA) has known benefits for health, stress reduction, and professiona...

Abstract Background A increase in average life expectancy leads us to an older population with multimorbidity. Understanding their self-care needs is essential for a response that promotes self-care with better health ou...

Abstract Objective Sickle cell anemia (SCA) is associated with substantial end‑organ morbidity, yet the circulating microRNA (miRNA) landscape in clinically stable, comorbidity‑free adults with SCA is poorly defined....

Abstract Background This study examined pharmaceutical needs in the subacute phase following the 2024 Noto Peninsula Earthquake, using dispensed prescriptions as a proxy. We described demand patterns, the dispensing time...