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Abstract Background A high prevalence of child overweight and obesity worldwide calls for innovative multi-setting intervention approaches, and thorough evaluation. This paper describes the protocol for the process evalu...

Abstract Background Optimization of biotechnological processes is traditionally limited by time-consuming trial-and-error approaches and the complexity of simultaneously optimizing multiple, often conflicting objectives....

Abstract Background Amid growing demands, workforce shortages, and rising costs, the evolving role of diagnostics—driven by technological innovation—underscores the urgent need to rethink the diagnostic process with ...

Abstract The global challenge of effectively cultivating clinical thinking in medical students persists, often hindered by traditional textbooks that present knowledge in a linear sequence disconnected from the non-linea...

Abstract Background Adaptive designs (ADs) are increasingly used, whereby outcome data accumulated during the trial may inform a trial’s course in accordance with pre-specified rules at interim analyses. The benefits h...