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23 resultados encontrados.

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A modular clinical thinking navigation system: an exploration in the ‘101 Project’ diagnostics textbook reform
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A modular clinical thinking navigation system: an exploration in the ‘101 Project’ diagnostics textbook reform
Rong Bi et al · BMC · 2026 · ISSN 1472-6920
Abstract The global challenge of effectively cultivating clinical thinking in medical students persists, often hindered by traditional textbooks that present knowledge in a linear sequence disconnected from the non-linea...
LCC TENDOlNwZWNpYWwgYXNwZWN0cyBvZiBlZHVjYXRpb24~; LCC:MedicineIdioma eng
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Trends of nucleic acid – based point-of-care diagnostics for infectious diseases
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Trends of nucleic acid – based point-of-care diagnostics for infectious diseases
Hossam Hatem et al · BMC · 2026 · ISSN 1754-1611
Abstract The global emergence and spread of infectious diseases highlights the importance of having an easily accessible, decentralized testing modality that is adept at quickly identifying the nucleic acids present in a...
LCC LCC:Biology (General)Idioma eng
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Measuring thyroid-stimulating hormone receptor antibodies using the IMMULITE® 2000 TSI assay is better than using the BRAHMS TRAK assay in an unselected clinical population, but both perform worse than expected: a real-world retrospective observational study
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Measuring thyroid-stimulating hormone receptor antibodies using the IMMULITE® 2000 TSI assay is better than using the BRAHMS TRAK assay in an unselected clinical population, but both perform worse than expected: a real-world retrospective observational study
Sofia Manousou et al · BMC · 2026 · ISSN 1756-6614
Abstract Background Graves’ hyperthyroidism is caused by stimulatory autoantibodies. Its diagnosis and monitoring are commonly based on measurement of thyrotropin receptor antibodies (TRAb) with unspecific immunoassays...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Case report: a case of CYBB gene variant in X-linked chronic granulomatous disease
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Case report: a case of CYBB gene variant in X-linked chronic granulomatous disease
Haiyan Lv et al · BMC · 2026 · ISSN 1471-2431
Abstract Chronic granulomatous disease (CGD) is an inherited immunodeficiency characterized by impaired phagocytic function due to defects in the NADPH oxidase complex. This enzymatic deficiency compromises the productio...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Clinical presentation of neurosyphilis – a single-center retrospective data analysis
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Clinical presentation of neurosyphilis – a single-center retrospective data analysis
Susanne Dyckhoff-Shen et al · BMC · 2026 · ISSN 2524-3489
Abstract Background As cases of neurosyphilis are rising worldwide – especially in people living with HIV (PLWH) – current data on clinical presentation, diagnostics and management of neurosyphilis in Europe are of h...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng
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Decision-support system for live detection of Leishmania parasites from microscopic images with deep learning
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Decision-support system for live detection of Leishmania parasites from microscopic images with deep learning
Juliane Pfeil et al · BMC · 2026 · ISSN 1471-2334
Abstract Background Leishmaniasis is a vector-borne parasitic disease caused by Leishmania protozoa. The disease manifests in several clinical presentations including cutaneous, mucocutaneous, and visceral leishmaniasis....
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Detection and differentiation of pestivirus antibodies in sheep and suckler cow herds in Southern Germany
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Detection and differentiation of pestivirus antibodies in sheep and suckler cow herds in Southern Germany
Judith Köster et al · BMC · 2026 · ISSN 1746-6148
Abstract Background Pestiviruses such as bovine viral diarrhea virus (BVDV) or the ovine border disease virus (BDV) are not strictly species-specific and can be transmitted between related animal species. Due to serologi...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Development and evaluation of an assay for the detection of tick-borne encephalitis virus RNA via real-time PCR with reverse transcription
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Development and evaluation of an assay for the detection of tick-borne encephalitis virus RNA via real-time PCR with reverse transcription
Alena Sharova et al · BMC · 2026 · ISSN 1756-3305
Abstract Background Tick-borne encephalitis virus (TBEV, Orthoflavivirus encephalitidis) is an arbovirus of the family Flaviviridae. It is the etiological agent of tick-borne encephalitis (TBE), a severe disease affectin...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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From gene to heart: the impact of a novel SGCD variant in familial dilated cardiomyopathy
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From gene to heart: the impact of a novel SGCD variant in familial dilated cardiomyopathy
Samira Kalayinia et al · BMC · 2026 · ISSN 1755-8794
Abstract Background Dilated cardiomyopathy (DCM) is a leading cause of heart failure, often resulting in reduced ejection fraction and progressive cardiac dysfunction. Although up to half of idiopathic DCM can be linked ...
LCC LCC:Internal medicine; LCC:GeneticsIdioma eng
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Institutional capacity for non-communicable disease care in Ghana’s primary health care system: a multi-method study
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Institutional capacity for non-communicable disease care in Ghana’s primary health care system: a multi-method study
Michel Adurayi Amenah et al · BMC · 2026 · ISSN 2731-4553
Abstract Background The burden of non-communicable diseases (NCDs), including hypertension, diabetes, and mental health conditions, is escalating in Ghana. Robust primary health care policies and effective health systems...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Nanomaterials for Alzheimer’s disease: emerging strategies in diagnosis and therapy
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Nanomaterials for Alzheimer’s disease: emerging strategies in diagnosis and therapy
Yue Na et al · BMC · 2026 · ISSN 1477-3155
Abstract Alzheimer’s disease (AD) is a prevalent and progressive neurodegenerative disease characterized by behavioral abnormalities, memory loss, and cognitive decline, presenting significant challenges for early diag...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Nanoplasmonic optical fiber sensing of SARS-CoV-2 nucleocapsid protein using an aptamer-DNA tetrahedron interface
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Nanoplasmonic optical fiber sensing of SARS-CoV-2 nucleocapsid protein using an aptamer-DNA tetrahedron interface
Xu Pin et al · BMC · 2026 · ISSN 1477-3155
Abstract Optical fiber sensing carries a number of potential advantages for diagnostics and biomarker detection and monitoring, yet particular challenges persist in linking molecular recognition events to a change in the...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Perspectives on innovation of the diagnostic process in general practice: Q-methodological study
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Perspectives on innovation of the diagnostic process in general practice: Q-methodological study
Esmée W.P. Vaes et al · BMC · 2026 · ISSN 2731-4553
Abstract Background Amid growing demands, workforce shortages, and rising costs, the evolving role of diagnostics—driven by technological innovation—underscores the urgent need to rethink the diagnostic process with ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Phenotypic and genomic profiling of multidrug-resistant Escherichia coli and Klebsiella pneumoniae isolated from Intensive Care Unit patients in Kenya
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Phenotypic and genomic profiling of multidrug-resistant Escherichia coli and Klebsiella pneumoniae isolated from Intensive Care Unit patients in Kenya
Beatrice Oduor et al · BMC · 2026 · ISSN 1471-2180
Abstract Background The global rise of multidrug-resistant Enterobacterales, particularly extended-spectrum beta-lactamase (ESBL)- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae, poses a critical ...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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ProQSAR: A modular and reproducible framework for small-data QSAR modeling with fit-and-use models
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ProQSAR: A modular and reproducible framework for small-data QSAR modeling with fit-and-use models
Tuyet-Minh Phan et al · BMC · 2026 · ISSN 1758-2946
Abstract Background Quantitative structure-activity relationship (QSAR) models are central to computer-aided drug discovery and predictive toxicology, but practical adoption is often impeded by ad-hoc tooling, inconsiste...
LCC TENDOkluZm9ybWF0aW9uIHRlY2hub2xvZ3k~; TENDOkNoZW1pc3RyeQ~~Idioma eng
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Public-Private Partnerships in tuberculosis service delivery in Somalia: a qualitative analysis
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Public-Private Partnerships in tuberculosis service delivery in Somalia: a qualitative analysis
Shafie Abdulkadir Hassan et al · BMC · 2026 · ISSN 1756-0500
Abstract Background Tuberculosis remains a major public health challenge in Somalia, where a fragile health system and reliance on private providers complicate care. Although Public-Private Partnerships are globally reco...
LCC LCC:Medicine; LCC:Biology (General); LCC:Science (General)Idioma eng
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Recall bias in population-based case-control studies of ovarian cancer and genital talcum powder use: potential impact and quantitative bias analysis
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Recall bias in population-based case-control studies of ovarian cancer and genital talcum powder use: potential impact and quantitative bias analysis
Diezhang Wu et al · BMC · 2026 · ISSN 1471-2288
Abstract Introduction Quantitative bias analysis (QBA) methods have been developed, with growing applications to epidemiological studies. Bayesian QBA (BQBA) methods may be superior in effectively using evidence-based pr...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Risk and protective factors for canine visceral leishmaniasis in the Americas: a systematic review update with meta-analysis
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Risk and protective factors for canine visceral leishmaniasis in the Americas: a systematic review update with meta-analysis
Anna Gabryela Sousa Duarte et al · BMC · 2026 · ISSN 1756-3305
Abstract Background Identification of risk and protective factors for canine visceral leishmaniasis (CVL) is essential to understand the epidemiology of the disease and direct prevention and control strategies. Building ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Severe pneumonia and bloodstream dissemination caused by Mycobacterium houstonense in a patient with achalasia: clinical importance of genospecies typing
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Severe pneumonia and bloodstream dissemination caused by Mycobacterium houstonense in a patient with achalasia: clinical importance of genospecies typing
Sieshem Bindraban et al · BMC · 2026 · ISSN 1471-2334
Abstract Background Infections caused by members of the Mycobacterium fortuitum complex are generally mild and confined to skin and soft tissues, while severe disease in immunocompetent individuals is uncommon. Within th...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Symptom clusters in ME/CFS reflect distinct neuroimmune and autonomic pathophysiological mechanisms: a translational model
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Symptom clusters in ME/CFS reflect distinct neuroimmune and autonomic pathophysiological mechanisms: a translational model
Lotte Habermann-Horstmeier et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disease characterized by heterogeneous symptom patterns. Previous work suggested that specific symptoms tend t...
LCC LCC:MedicineIdioma eng
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Temporal and regional trends in the diagnosis and treatment of spontaneous intracranial hypotension: a systematic review
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Temporal and regional trends in the diagnosis and treatment of spontaneous intracranial hypotension: a systematic review
Woo-Seok Ha et al · BMC · 2026 · ISSN 1129-2377
Abstract Background Spontaneous intracranial hypotension (SIH) is an underrecognized condition with rapidly evolving diagnostic and therapeutic strategies. This study investigated temporal and regional trends in diagnost...
LCC LCC:MedicineIdioma eng
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The Valdivia Project: genetic characterization of a unique Wolfram Syndrome cluster in coastal Ecuador
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The Valdivia Project: genetic characterization of a unique Wolfram Syndrome cluster in coastal Ecuador
Josefa E. Palacio et al · BMC · 2026 · ISSN 1750-1172
Abstract Objective This study aims to document the first genetically confirmed cases of WS1 in Ecuador. Design and methods A Cross-Sectional study was conducted among individuals with early-onset insulin-dependent diabet...
LCC LCC:MedicineIdioma eng
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The role of sleep disorders in the motoric and cognitive trajectories of older physically frail sarcopenic and healthy active subjects: SOMNUS-DARE, a prospective cohort study
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The role of sleep disorders in the motoric and cognitive trajectories of older physically frail sarcopenic and healthy active subjects: SOMNUS-DARE, a prospective cohort study
Marco Salvi et al · BMC · 2026 · ISSN 1471-2318
Abstract Background Sarcopenia, altered bone and systemic metabolism, physical frailty and cognitive decline are age-dependent and interrelated phenomena. Sleep disorders which are erroneously considered as part of the a...
LCC TENDOkdlcmlhdHJpY3M~Idioma eng
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