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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges

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Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges

Kohei Okuyama et al · BMC · 2026 · ISSN 1476-4598

Abstract Immune checkpoint inhibitors (ICIs) have fundamentally altered the therapeutic paradigm for head and neck squamous cell carcinoma (HNSCC); however, durable clinical benefit remains limited to biologically define...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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The effect of quantitative goal exercise combined with whole process refined nutrition management on the nutritional status and quality of life of head and neck cancer patients undergoing radiotherapy: an open-label, randomized, controlled trial

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Juanli Shi et al · BMC · 2026 · ISSN 1748-717X

Abstract Objective To explore the clinical effect of a combined intervention comprising Quantitative Goal Exercise (QGE) and Whole-Process Refined Nutrition Management (WP-RNM) on patients with head and neck cancer under...

LCC TENDOk1lZGljYWwgcGh5c2ljcy4gTWVkaWNhbCByYWRpb2xvZ3kuIE51Y2xlYXIgbWVkaWNpbmU~; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neSIdioma eng

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The influence of brachytherapy on tooth development: a longitudinal study of pediatric head and neck tumor survivors

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The influence of brachytherapy on tooth development: a longitudinal study of pediatric head and neck tumor survivors

Guohao Zhang et al · BMC · 2026 · ISSN 1472-6831

Abstract Background Interstitial brachytherapy is an effective and organ-preserving radiotherapeutic modality for pediatric and adolescent patients with head and neck tumors, offering favorable outcomes with minimal impa...

LCC TENDOkRlbnRpc3RyeQ~~Idioma eng

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[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma

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[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma

Stefan Stoiber et al · BMC · 2026 · ISSN 1476-4598

Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous malignancy with limited predictive markers to guide personalized treatment, particularly in human papillomavirus (HPV)-negative cases, whic...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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Intra- and inter-rater reliability of goniometric head posture measurement in patients with neck pain and hamstring tightness

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Intra- and inter-rater reliability of goniometric head posture measurement in patients with neck pain and hamstring tightness

Aftab Ahmed Mirza Baig et al · BMC · 2026 · ISSN 1471-2474

Abstract Background Neck pain (NP) is a common disabling condition, often associated with forward head posture (FHP) and hamstring tightness. There is limitation in evidence regarding the intrarater and interrater reliab...

LCC LCC:Diseases of the musculoskeletal systemIdioma eng

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Self-reported tooth loss and quality of life among household heads of Jwalamukhi, Dhading, Nepal

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Self-reported tooth loss and quality of life among household heads of Jwalamukhi, Dhading, Nepal

Sirjana Dahal et al · BMC · 2026 · ISSN 1472-6831

Abstract Background Tooth loss remains a significant public health burden in developing countries like Nepal. Since teeth are vital to mastication, speech, and facial esthetics, tooth loss can have a major impact both on...

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Dynamic effects of low- and high-pressure pneumoperitoneum on optic nerve sheath diameter during laparoscopic cholecystectomy: a prospective, randomized, observer-blinded clinical trial

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Dynamic effects of low- and high-pressure pneumoperitoneum on optic nerve sheath diameter during laparoscopic cholecystectomy: a prospective, randomized, observer-blinded clinical trial

Engin Cetin et al · BMC · 2026 · ISSN 1471-2253

Abstract Background This study aimed to compare the time-dependent changes in optic nerve sheath diameter (ONSD) associated with low-pressure (8 mmHg) and high-pressure (14 mmHg) pneumoperitoneum during laparoscopic ch...

LCC LCC:AnesthesiologyIdioma eng

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