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Impact of adverse events-associated dose modifications of PARP inhibitors on treatment outcomes in primary ovarian cancer
Artículo
Acceso abierto Artículo DOAJ
Impact of adverse events-associated dose modifications of PARP inhibitors on treatment outcomes in primary ovarian cancer
Yue Fu et al · BMC · 2026 · ISSN 1757-2215
Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPis) are the standard of care for primary ovarian cancer (OC), yet adverse events (AEs) frequently necessitate dose modifications. The prognostic impact of ...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
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Inpatient safety, effectiveness of SGLT2 inhibitors and GLP-1 RAs in type 2 diabetes: ENDOCARE, a pragmatic prospective cohort study
Artículo
Acceso abierto Artículo DOAJ
Inpatient safety, effectiveness of SGLT2 inhibitors and GLP-1 RAs in type 2 diabetes: ENDOCARE, a pragmatic prospective cohort study
Óscar Moreno-Pérez et al · BMC · 2026 · ISSN 1475-2840
Abstract Background Current guidelines recommend baseline insulin as the standard treatment for most people hospitalised with type 2 diabetes (PWT2D). However, they generally discourage the use of sodium–glucose cotran...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Impact of a structured nurse-delivered multi component SGLT2 inhibitor initiation and optimization pathway on kidney function and clinical outcomes in type 2 diabetes and chronic kidney disease: a real-world retrospective study
Artículo
Acceso abierto Artículo DOAJ
Impact of a structured nurse-delivered multi component SGLT2 inhibitor initiation and optimization pathway on kidney function and clinical outcomes in type 2 diabetes and chronic kidney disease: a real-world retrospective study
Liang Huang et al · BMC · 2026 · ISSN 1471-2369
Abstract Background The implementation gap between evidence-based SGLT2 inhibitor therapy and real-world practice remains substantial in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). Pro...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBnZW5pdG91cmluYXJ5IHN5c3RlbS4gVXJvbG9neQ~~Idioma eng
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Nivolumab rechallenge after pituitary apoplexy associated with nivolumab plus ipilimumab in a patient with pituitary adenoma and rectal melanoma: a case report and literature review
Artículo
Acceso abierto Artículo DOAJ
Nivolumab rechallenge after pituitary apoplexy associated with nivolumab plus ipilimumab in a patient with pituitary adenoma and rectal melanoma: a case report and literature review
Chiaki Imai et al · BMC · 2026 · ISSN 2055-0294
Abstract Background The overall incidence of pituitary apoplexy among patients with pituitary adenoma ranges from 0.6% to 7.0%, although many cases likely go undiagnosed. Several precipitating factors have been identifie...
LCC LCC:Therapeutics. Pharmacology; TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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The genetic landscape of breast cancer in young women from Morocco: implications for diagnosis and treatment
Artículo
Acceso abierto Artículo DOAJ
The genetic landscape of breast cancer in young women from Morocco: implications for diagnosis and treatment
Brahim El Hejjioui et al · BMC · 2026 · ISSN 1755-8794
Abstract Mortality rates from breast cancer in young women have fallen considerably in high-income countries but continue to rise in low-income countries such as Morocco. Young women with breast cancer face unique challe...
LCC LCC:Internal medicine; LCC:GeneticsIdioma eng
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A 13-gene prognostic model developed using machine learning to predict the response to neoadjuvant chemoradiotherapy in rectal carcinoma
Artículo
Acceso abierto Artículo DOAJ
A 13-gene prognostic model developed using machine learning to predict the response to neoadjuvant chemoradiotherapy in rectal carcinoma
Zhanhua Gao et al · BMC · 2026 · ISSN 1475-2867
Abstract Backgrounds Neoadjuvant chemoradiation (nCRT) is a standard treatment for rectal carcinoma that reduces tumor size and local recurrence while improving the rate of sphincter preservation. However, many patients ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~; LCC:CytologyIdioma eng
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Benefits of sacubitril/valsartan alone and in combination with dapagliflozin in a preclinical female model of cardiometabolic and age-related cardiac dysfunction
Artículo
Material complementario disponible Artículo DOAJ
Benefits of sacubitril/valsartan alone and in combination with dapagliflozin in a preclinical female model of cardiometabolic and age-related cardiac dysfunction
Elena Mele et al · BMC · 2026 · ISSN 1475-2840
Abstract Background Heart failure with preserved ejection fraction (HFpEF) disproportionately affects elderly women and is closely associated with central obesity and metabolic dysfunction. Although sodium-glucose co-tra...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Response mechanisms of xylitol-producing Saccharomyces cerevisiae strains to acetic acid and furfural and the role of SPI1, CTT1, and CLB1 in tolerance
Artículo
Acceso abierto Artículo DOAJ
Response mechanisms of xylitol-producing Saccharomyces cerevisiae strains to acetic acid and furfural and the role of SPI1, CTT1, and CLB1 in tolerance
Yu-Ping Xia et al · BMC · 2026 · ISSN 1475-2859
Abstract Background The efficient bioconversion of lignocellulosic hydrolysates to xylitol is hampered by inhibitors such as acetic acid and furfural. This study investigated the response mechanisms of two engineered xyl...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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The efficacy and safety of novel antidiabetic agents in polycystic ovary syndrome: a network meta-analysis
Artículo
Acceso abierto Artículo DOAJ
The efficacy and safety of novel antidiabetic agents in polycystic ovary syndrome: a network meta-analysis
Junjie Lin et al · BMC · 2026 · ISSN 1757-2215
Abstract Background Polycystic ovary syndrome (PCOS) is characterised by insulin resistance and hyperandrogenism; whether novel antidiabetic drugs differentially improve these metabolic and reproductive disturbances rema...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
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