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Abstract Background Environmental studies often evaluate how exposures influence health outcomes through intermediate biological processes. In practice, researchers are often interested in complex exposure mixtures rathe...

Abstract The complexity of student social adaptability development mechanisms in the context of physical education reform urgently requires in-depth exploration. Grounded in self-determination theory as the primary theor...

Abstract Purpose This study examined the associations between moderate-to-vigorous intensity physical activity (MVPA) and social support (SS), autonomous motivation (AM), community environment (CE), school environment (S...

Abstract Introduction Different pre-pregnancy body mass index (BMI) may lead to adverse pregnancy complications and unfavorable outcomes, but few studies focus on preterm infants under 32 gestational weeks. The associate...

Abstract The aim of this cross-sectional study is to examine the mediating role of political interest in the association between life satisfaction and political participation and the moderating role of individuals' polit...

Abstract Background Research on career calling has predominantly focused on its positive outcomes for well-being and professional development. However, investigations into its antecedents remain limited, particularly wit...

Abstract Objective This study investigates how negative life events affect sleep quality among Chinese college students, focusing on the sequential roles of coping styles (positive and negative) and rumination as linking...

Abstract Background Intrinsic capacity (IC) serves as an integrative measure of biological reserve, and physical activity (PA) is a key modifiable determinant of cardiovascular health. The joint association of IC and PA ...

Abstract Background Chronic obstructive pulmonary disease (COPD) is a major global health burden, with emerging evidence implicating gut microbiota dysbiosis via the gut-lung axis. The Dietary Index for Gut Microbiota (D...

Abstract Background This study explores whether internalizing and externalizing behaviors mediate the association between adolescent social media use and novel psychoactive substance (NPS) use in Australia, addressing a ...

Abstract Background Childhood trauma is a well-established risk factor for greater severity and poorer prognosis of bipolar depression. While anhedonia particularly in the social domain is theorized to link early adversi...

Abstract Objectives To characterize white matter microstructural abnormalities in thyroid eye disease (TED) using tract-based spatial statistics (TBSS) of diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DK...

Abstract Background Nurses frequently care for patients at the end of life, yet many lack adequate preparation to manage the associated emotional challenges. Attitudes toward death influence both the quality of end-of-li...

Abstract Background Chronic liver disease (CLD) and heart disease (HD) are major contributors to global morbidity and mortality. Although increasing evidence supports close interactions between the liver and heart, popul...

Abstract Background Perinatal depression (PD) is classified into four subtypes: pregnancy, early postpartum, late postpartum, and chronic, based on depressive symptom trajectories, with each subtype potentially involving...

Abstract Celebrity worship has become increasingly prevalent, yet the psychological patterns related to this behaviour remain unclear. This study investigated psychological emptiness as a central pattern linking social e...

Abstract Background Ambient air pollution has been linked to atrial fibrillation (AF), yet the underlying metabolic mechanisms remain poorly understood. Methods We analyzed 227,324 UK Biobank participants without baselin...

Abstract Background Visceral obesity contributes to hypertension through pathways of insulin resistance and inflammation. The joint association of C-reactive protein-triglyceride-glucose index (CTI), which integrates the...

Abstract Background Gallstone disease exhibits a marked sex difference. While obesity and female sex hormones are known risk factors, the role of sex hormone-binding globulin (SHBG) and testosterone in gallstone-related ...