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Abstract Background Body pain significantly affects the quality of life. However, the relationship between headache and pain across broad body regions remains unclear. This population-based cross-sectional study aimed to...

Abstract Background Postoperative sleep disturbances are common and have been shown to exacerbate incisional pain by enhancing the central nervous system’s excitability. However, the specific neural circuit mechanisms ...

Abstract Background Breastfeeding is an unrivaled way of providing ideal food for healthy growth and development of infants. However, as important as breastfeeding is for the child’s health, it can affect the mother’...

Abstract Introduction Kinesio taping (KT) is used after mandibular third-molar surgery, yet its benefits and time course remain uncertain. We evaluated whether KT reduces pain, swelling, and trismus versus no tape. Metho...

Abstract Background Port-A-Cath needle insertion in pediatric chemotherapy is often painful and stressing. Distraction is a non-pharmacological method of pain management in invasive procedures in children. The purpose of...

Abstract Background Low back pain and temporomandibular Dysfunction (TMD) have a coexistence in clinical practice. To find the effect of temporomandibular exercises (TME) along with conventional physiotherapy in patient...

Abstract Background The study aimed to determine the effect of manual pressure and local cold spray administration on pain intensity and satisfaction in reducing pain due to Human Anti-D Immunoglobulin injection administ...

Abstract Background The insular cortex (IC), a pivotal hub for pain signal integration, projects extensively to the thalamus. However, the functional role of its specific projection to the central medial thalamic nucleus...

Abstract Background It is estimated that almost all women undergoing cesarean section experience some pain in the immediate postpartum period. In the face of pain that limits self-care and care for the newborn, antalgic ...

Abstract Background Chronic low back pain (CLBP) is a common musculoskeletal symptom associated with spinal disorders, impairing quality of life while imposing significant medical and socioeconomic burdens. Traditional l...

Abstract Background Neuropsychiatric symptoms (NPS) are highly prevalent in nursing home residents. The main aims of this study were to examine whether music-based care (MBC) had sustained effects on NPS in nursing home ...

Abstract Background Chronic neuropathic pain is frequently accompanied by anxiety and depression, yet the cortical circuit mechanisms underlying this comorbidity remain unclear. The medial orbitofrontal cortex (mOFC) is ...

Abstract Background Altered pain processing and central sensitization are key mechanisms underlying migraine. Although quantitative sensory testing (QST) objectively assesses sensory thresholds, its clinical implications...

Abstract Background Some studies regarding patients complaining of residual pain after total knee arthroplasty (TKA) showed pain scores improvement using genicular nerve radiofrequency ablation (GNRFA). This prompted the...

Abstract Background Postherpetic neuralgia (PHN) is a neuropathic pain syndrome that can be resistant to traditional therapies and severely impairs quality of life. The serratus posterior superior intercostal plane block...

Abstract Background Acute hepatic porphyria (AHP) is a heme metabolism disorder characterized by acute abdominal pain episodes, with diagnostic delays and misdiagnosis due to heterogeneous presentations and symptom overl...

Abstract Background Ankle arthrodesis is an established procedure for end-stage ankle osteoarthritis. Besides the known limited functionality, gait and foot arch changes are accompanying pathologies, which are little inv...

Abstract Background Patient reported outcome measure (PROM) use is a marker of high-quality chiropractic care. Limited information exists regarding use of PROMs by United States chiropractors, especially within integrate...

Abstract Background Attention deficit hyperactivity disorder is a common disorder that has an association with fibromyalgia. The connection between the two is incompletely understood but may be due to specific neurotrans...

Abstract Background Traumeel (Tr14) and diclofenac gels are commonly prescribed topical treatments for Grade I-II acute lateral ankle sprain (LAS). A meta-analysis of two multi-center trials was performed to compare thei...