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BackgroundApproximately 40-60% of patients with locally advanced esophageal squamous cell carcinoma (ESCC) exhibit suboptimal responses to neoadjuvant chemoimmunotherapy (NCIT), highlighting the need for predictive bioma...

ObjectiveTo investigate the MRI features of different pathological types in adult and juvenile patients with craniopharyngioma.Materials and methodsThe preoperative MRI images of 68 patients with pathologically confirmed...

ObjectiveThis study aimed to investigate the prognostic factors of endoscopic submucosal dissection (ESD) in early colorectal cancer patients and to develop a predictive model for assessing prognostic risk.MethodsWe retr...

IntroductionAccurate segmentation of retinal blood vessels is essential for the early diagnosis of ophthalmic and systemic diseases such as diabetes, hypertension, and cardiovascular disorders. However, challenges such a...

IntroductionTumor complexity scoring supports preoperative planning for robot-assisted partial nephrectomy (RAPN), but evidence in larger tumors is limited. We evaluated whether PADUA and RENAL nephrometry scores are ass...

Transdifferentiated melanoma is a rare variant of melanoma characterized by phenotypic plasticity, loss of conventional melanocytic markers, and acquisition of features from other tissue lineages, often associated with a...

BackgroundHypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiovascular conditions, which may be linked to ion channel dysfunction. In decades, Genetic studies in HCM patients have shown that multipl...

AimTo clarify the molecular mechanisms through which lobetyolin (LT) modifies the gut microbiota-bile acid axis to multitarget the regulation of hyperandrogenism, insulin resistance, chronic low-grade inflammation, and e...

Gambling disorder or pathological gambling is a psychiatric disorder with severe and wide-ranging consequences for the affected individual and their surroundings. While no pharmacological treatment has yet been officiall...

IntroductionMetabolism-associated fatty liver disease (MAFLD) has emerged as a severe worldwide public health burden with insufficient available clinical therapeutic strategies, which underscores the urgent demand for sa...

ObjectiveTo evaluate the diagnostic value of 3.0 T endovaginal coil magnetic resonance imaging technique for early cervical cancer.MethodsForty patients with early cervical cancer admitted to the gynecology department ...

Background Lupus nephritis (LN) is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), and the accurate classification of renal pathological subtypes is crucial for reducing mortality rates ...

ObjectiveThe present investigation is designed to assess the synergistic impact of endoscopic ultrasonography (EUS)paired with endoscopic therapy in addressing upper gastrointestinal (GI) lesions that protrude.MethodsOur...