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BackgroundGranular cell astrocytoma (GCA) is a rare, morphologically distinct variant of IDH-wildtype glioblastoma that can appear deceptively low-grade yet behave aggressively. Its molecular features remain poorly defin...

Malignant solid tumors of the gastrointestinal tract are clinically rare in children, with malignant solid tumors of the esophagus being particularly uncommon. Clinical reports on esophageal cancer in children are extrem...

IntroductionBone-seeking radiopharmaceuticals are the treatment of choice with clinical benefits for patients with extensive skeletal metastases, but they can also cause serious radiation-related adverse events (rrAEs). ...

Two adult domestic shorthair cats were evaluated for progressive neurologic deficits caused by spinal cord compression secondary to vertebral osteosarcoma, giant-cell subtype. Feline giant cell osteosarcoma represents a ...

Mucopolysaccharidosis type II (MPS II) is an X-linked recessive lysosomal storage metabolic disorder caused by pathogenic mutations in the iduronate-2-sulfatase (IDS) gene. Herein, we report the case of a 2-year-old male...

BackgroundRare epidermal growth factor receptor (EGFR) mutations have a low incidence, and their response to EGFR tyrosine kinase inhibitors (TKI) has not been sufficiently studied. L747P is a rare EGFR mutation located ...

BackgroundPulmonary Epstein–Barr virus-associated smooth muscle tumor (EBV-SMT) is extremely rare in children with congenital immunodeficiency. This case report describes the clinical details of a pediatric pulmonary E...

IntroductionLarge language models (LLMs) may support clinical reasoning, yet real-world outpatient studies integrating structured clinical data with chest radiographs (CXRs) remain limited. We compared three LLMs for pul...

BackgroundParathyroid carcinoma (PC) is a rare and often misdiagnosed endocrine malignancy that can present with diverse clinical manifestations, complicating its detection and management.Case presentationThis case repor...

ObjectiveThis study aimed to investigate the prognostic factors of endoscopic submucosal dissection (ESD) in early colorectal cancer patients and to develop a predictive model for assessing prognostic risk.MethodsWe retr...

PurposesGene mutations identified through next-generation sequencing (NGS) have been increasingly recognised for their clinical significance in myeloid malignancies. However, data concerning Chinese populations remain li...

IntroductionDesmoid tumors, also known as aggressive fibromatosis, are rare, locally invasive soft tissue neoplasms characterized by clonal fibroblastic proliferation without metastatic potential. Gamma secretase inhibit...

ObjectiveThe present investigation is designed to assess the synergistic impact of endoscopic ultrasonography (EUS)paired with endoscopic therapy in addressing upper gastrointestinal (GI) lesions that protrude.MethodsOur...

ObjectiveThis study aimed to investigate the current degree of skin photoaging in young Asian women and to explore the intervention effects of non-ablative bipolar radiofrequency (RF) combined with ablative fractional CO...