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Introduction:Orthopedic and musculoskeletal pain is a leading cause of disability worldwide, and many patients continue to experience suboptimal relief despite advances in pharmacological and physical therapies. Magnetic...

BackgroundStem cell therapy holds considerable potential for treating dry eye syndrome, though it has yet to receive clinical approval.AimThis paper systematically quantifies the efficacy and safety of stem cell-based th...

BackgroundEarly and effective intervention is crucial in the management of acute ischemic stroke (AIS) without large- or medium-vessel occlusion (non-LVO/MVO), which accounts for approximately 60–70% of all AIS cases. ...

ObjectivesTo conduct a scoping review mapping the extent, nature, and consistency of available evidence regarding the effects of sodium–glucose cotransporter-2 (SGLT2) inhibitors on kidney function, proteinuria, kidney...

BackgroundYupingfeng Powder (YPF), a classical Chinese herbal formula composed of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata, has demonstrated potential efficacy in the treatment of ...

MethodsUp to October 2025, a systematic search was conducted in PubMed, Embase, and Web of Science. Eligible studies included patients with confirmed breast fibroadenoma treated with high-intensity focused ultrasound (HI...

BackgroundAccurate detection and monitoring of the oestrous cycle in West African Dwarf (WAD) goats is indispensable for reproductive management. Vaginal cytology is commonly used, but different collection methods may va...

BackgroundMigraine is a prevalent neurological condition, affecting approximately 14% of the population, and is a leading cause of disability. Conventional treatments may have limited efficacy and tolerability limitation...

BackgroundTransarterial chemoembolization (TACE) is a standard treatment for intermediate-stage hepatocellular carcinoma (HCC), but its efficacy varies due to patient heterogeneity. Combining TACE with systemic therapies...

ObjectiveTo develop a Health Action Process Approach (HAPA) based exercise rehabilitation program for chronic heart failure (CHF) patients and evaluate its effectiveness.MethodsA randomized controlled trial was carried o...

Against the backdrop of increasingly frequent global educational exchanges, the issue of international students’ school adjustment has attracted much attention. The rise of Generative AI (GenAI) has brought new perspec...

ObjectiveChronic pain, a major global public health burden, is primarily driven by altered central pain processing, which conventional treatments rarely target directly. This systematic review and meta-analysis synthesiz...

Background/objectivesAcupuncture is recommended for the treatment of cancer-related fatigue (CRF), but the strength of evidence remains limited. This study aims to comprehensively update the evaluation of the effectivene...

ObjectiveTo systematically evaluate the effects of exercise therapies such as aerobic exercise (CAE), Tai Chi (TC), Baduanjin (BDJ), resistance training (RE), Wuqinxi (WQX), yoga (YG), and rehabilitation training (RT) on...

The therapeutic efficacy of Mesenchymal Stromal Cells (MSCs) has been demonstrated in a multitude of pre-clinical studies and clinical trials, yet the translation of MSC therapies is limited by biological factors such as...

Pharmacogenetics has redefined the understanding of antidepressant response by demonstrating that genetic variability profoundly influences both drug efficacy and safety. This review synthesizes current evidence on the i...

ObjectiveSensory gait ataxia is a core feature of chronic peripheral vestibular disorders, leading to impaired mobility, reduced quality of life, and increased fall risk. Quantitative gait metrics capturing this deficit ...

ObjectiveThis systematic review and meta-analysis synthesize preclinical evidence to evaluate the therapeutic efficacy of sinomenine in rodent models of rheumatoid arthritis, and integrate current understanding of its po...