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The escalating prevalence of overweight and obesity among young and middle-aged adults constitutes a significant public health challenge. While modifying dietary behavior is accepted as a critical component of weight man...

BackgroundMost research on social media use and depression has focused on young adults. A few studies in middle-aged and older Chinese adults have reported a negative association, but the underlying mechanisms remain unc...

BackgroundFrailty is a complex age-related clinical syndrome characterized by diminished physiological reserve and increased vulnerability to stressors. Cognitive function may be associated with frailty; however, evidenc...

ObjectiveTo examine the heterogeneity and determinants of Traditional Chinese Medicine Health Literacy (TCM-HL) among middle-aged and older adults patients with chronic diseases and its association with disease burden an...

Early adversity programs induce changes that can accelerate biological aging. Using the early stress model of maternal separation (MS), we assessed oxidative, metabolic, and biochemical consequences in serum derived from...

BackgroundHigh blood pressure (BP) is a known risk factor for dementia, but the relationships between BP and gross brain volumes are mixed and are understudied in groups who are at particularly high risk for dementia, su...

IntroductionHIV testing is central to early diagnosis and HIV prevention, yet uptake among youth remains suboptimal in many low- and middle-income countries. Our study examined HIV testing uptake and its associated facto...

BackgroundHormone-sensitive cancers (HSCs) pose a significant threat to women’s health, with global rising incidence rates. This study provides the most up-to-date assessment of the global burden of HSCs.MethodsWe retr...

IntroductionA research gap exists regarding the association between non-optimal ambient temperature (NOAT) and early childhood development (ECD) in low- and middle-income countries (LMICs). This study investigates the as...

ObjectiveThis study aimed to investigate the long-term effects of chronic sleep deprivation (CSD) on the bone mineral density (BMD), bone microarchitecture, biomechanical properties and body weight of middle-aged and old...

IntroductionParkinson’s disease (PD) is the second most common neurodegenerative disorder. The risk of frailty is significantly higher in patients with PD than in age-matched individuals without PD. This study aimed to...

Humor is a universal human experience, enjoyed and expressed across all stages of life. While numerous studies have explored the developmental aspects of humor, relatively little research has focused on humor in older ad...