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Discovering TEAD4 modulators for hepatocellular carcinoma: a GAN-enabled generative modelling framework

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Discovering TEAD4 modulators for hepatocellular carcinoma: a GAN-enabled generative modelling framework

Varshni Premnath et al · Frontiers Media S.A · 2026 · ISSN 2673-7647

IntroductionLiver diseases continue to impose a major global health burden, and therapeutic progress is constrained by the limited availability of validated small-molecule modulators. TEAD4, a central Hippo-YAP effector,...

LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng

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Development and internal validation of a machine learning model for predicting intracranial infection after spontaneous intracerebral hemorrhage: a two-center retrospective study

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Development and internal validation of a machine learning model for predicting intracranial infection after spontaneous intracerebral hemorrhage: a two-center retrospective study

Yizhao Lin et al · Frontiers Media S.A · 2026 · ISSN 1664-2295

BackgroundIntracranial infection (ICI) is a serious complication following spontaneous intracerebral hemorrhage (ICH) and is associated with prolonged intensive care, increased morbidity, and poor functional outcomes. Ea...

LCC LCC:Neurology. Diseases of the nervous systemIdioma eng

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