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ObjectiveChronic pain, a major global public health burden, is primarily driven by altered central pain processing, which conventional treatments rarely target directly. This systematic review and meta-analysis synthesiz...

BackgroundPatients with rheumatoid arthritis (RA) and concomitant fibromyalgia (FM) frequently experience severe, refractory pain, elevated disease activity scores, and substantial psychological distress. Conventional tr...

BackgroundChronic low back pain (CLBP), with or without radicular pain (RP), is a major cause of disability and reduced quality of life. Psychological comorbidities such as depression, anxiety, and chronic pain disorder ...

ObjectiveTo investigate the safety and efficacy of magnesium sulfate as an adjuvant in pulsed radiofrequency (PRF) stimulation of the greater occipital nerve for the treatment of occipital neuralgia.MethodsConsecutive pa...

BackgroundFibromyalgia affects 2%–8% of the global population with suboptimal treatment outcomes. Emerging evidence suggests histamine intolerance, mediated by diamine oxidase (DAO) deficiency, may contribute to fibrom...

BackgroundHip fractures in older adults are costly and often fatal. Cognitive impairment (CI) complicates pain assessment, raises delirium risk, and hinders early mobilization and rehabilitation. This review synthesizes ...

ObjectiveTo assess the effectiveness of a four-week trimodal prehabilitation program in enhancing the quality of life, clinical symptoms, and negative emotions of stage IV triple-negative breast cancer patients who are u...

Stroke survivors frequently experience sleep disturbance, among which post-stroke insomnia (PSI) is common yet often underrecognized across the post-stroke course. Although its clinical expression may vary over time, PSI...

Poststroke anxiety and depression (PSAD/PSAnx) are common and heterogeneous emotional disorders among stroke survivors, significantly impacting functional recovery, quality of life, and long term prognosis. Their pathoge...

Recurrent polychondritis (RP) is a rare systemic autoimmune disorder that rarely involves the central nervous system (CNS). This report describes a 68-year-old male RP patient who was admitted with bilateral auricular sw...

IntroductionMusic-induced analgesia (MIA) has significant clinical value for patients with fibromyalgia (FM) and serves as a key model for understanding the complex neural mechanisms underlying the effects of music on ph...