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BackgroundPatients with rheumatoid arthritis (RA) and concomitant fibromyalgia (FM) frequently experience severe, refractory pain, elevated disease activity scores, and substantial psychological distress. Conventional tr...

ObjectiveTo evaluate the effects of various transcranial magnetic stimulation (TMS) parameters—including stimulation duration, intensity, pulse number, frequency, and target region—on pain scores in patients with neu...

ObjectiveThe purpose of this study was to evaluate the efficacy and safety of Nalbuphine compared to Pethidine for pain relief during oocyte retrieval.MethodsIn a double-blinded, non-inferiority randomized controlled tri...

BackgroundPerinatal sleep disturbance is highly prevalent among women undergoing elective cesarean section. Dexmedetomidine has been proven effective in improving sleep quality in patients undergoing general surgery, and...

Introduction:Orthopedic and musculoskeletal pain is a leading cause of disability worldwide, and many patients continue to experience suboptimal relief despite advances in pharmacological and physical therapies. Magnetic...

BackgroundDespite being a minimally invasive procedure, laparoscopic appendectomy (LA) frequently induces substantial postoperative pain in children. While erector spinae plane block (ESPB) has demonstrated efficacy for ...

ObjectiveTo investigate the safety and efficacy of magnesium sulfate as an adjuvant in pulsed radiofrequency (PRF) stimulation of the greater occipital nerve for the treatment of occipital neuralgia.MethodsConsecutive pa...

IntroductionCyclin-dependent kinase 5 (Cdk5) plays a critical role in pain transmission by phosphorylating key nociceptive proteins. One of its recently identified substrates, the P2X2 subunit, is part of the P2X2/3 puri...

BackgroundFibromyalgia affects 2%–8% of the global population with suboptimal treatment outcomes. Emerging evidence suggests histamine intolerance, mediated by diamine oxidase (DAO) deficiency, may contribute to fibrom...

BackgroundMigraine is a prevalent neurological condition, affecting approximately 14% of the population, and is a leading cause of disability. Conventional treatments may have limited efficacy and tolerability limitation...

ObjectiveTo assess the effectiveness of a four-week trimodal prehabilitation program in enhancing the quality of life, clinical symptoms, and negative emotions of stage IV triple-negative breast cancer patients who are u...