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Adapting CAR-T and CAR-Treg cancer therapies for autoimmunity: innovations and challenges

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Adapting CAR-T and CAR-Treg cancer therapies for autoimmunity: innovations and challenges

Michael D. Lovelace et al · Frontiers Media S.A · 2026 · ISSN 1664-3224

The application of Chimeric Antigen Receptor T-cell (CAR-T), CAR-engineered regulatory T cell (CAR-Treg) and hematopoietic stem cell (HSC) therapies has grown in recent years, driven by an increasing demand for robust, a...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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PARylation-centric crosstalk: orchestrating immune evasion and multidrug resistance in ovarian cancer

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PARylation-centric crosstalk: orchestrating immune evasion and multidrug resistance in ovarian cancer

Lin Hou et al · Frontiers Media S.A · 2026 · ISSN 1664-3224

Post-translational modifications (PTMs) play pivotal roles in ovarian cancer pathogenesis, with poly(ADP-ribosyl)ation (PARylation) serving as a key regulator of DNA repair, immune evasion, and therapeutic resistance. Be...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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