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Bone and cartilage regeneration can be improved by designing a functionalized biomaterial that includes bioactive drugs in a biocompatible and biodegradable scaffold. Based on our previous studies, we designed a vanadium...

Aims. Posttranslational modifications of histones and transcription factors regulate gene expression and are implicated in beta-cell failure and diabetes. We have recently shown that preserving H3K27 and H3K4 methylation...

In the last decades there have been significant advances in our understanding of the cellular and subcellular mechanisms underlying changes in synaptic connectivity that subserve memory formation. The so called Theory of...

Photodynamic therapy (PDT) is a treatment modality for tumours and other accessible lesions based on the combination of light and a photosensitizer (PS) accumulated in the target tissue. The main disadvantage of PDT is P...

Timing is everything. That's especially true when it comes to the activation of enzymes created by the pancreas to break down food. Pancreatic enzymes are packed in secretory granules as precursor molecules called zymoge...

Context. Meditation incorporation helps to fight against disorders such as depression, stress, and anxiety. Specifically, few studies have studied Osho's Active Meditation on young people, but observed evidence using pas...

There is an increasing need for the injection to the grid of renewable energy; therefore, to evaluate the optimal location of new renewable generation is an important task. The primary purpose of this work is to develop ...